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Journal / Immunology and Infection / Mekanistisk insikt i utvecklingen av…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Mekanistisk insikt i utvecklingen av TNBS-medierad intestinal fibros och utvärdering av de hämmande effekterna av rapamycin
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Mekanistisk insikt i utvecklingen av TNBS-medierad intestinal fibros och utvärdering av de hämmande effekterna av rapamycin

Article DOI: 10.3791/60067-v • 10:21 min • September 12th, 2019
September 12th, 2019 •
1,2,3, 4, 4, 4, 1,2
1Department of Molecular and Cellular Physiology, Albany Medical College, 2The IBD Center, Division of Gastroenterology, Department of Medicine, Albany Medical College, 3Department of Geriatrics, School of Medicine and Health Science, University of North Dakota, 4Department of Neuroscience and Experimental Therapeutics, Albany Medical College

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I denna studie beskriver vi ett detaljerat förfarande av TNBS-medierad intestinal fibros, som uppvisar jämförbar patofysiologi till Crohns fibros. Vi diskuterar också denna strategi mot bakgrund av rapamycin underlättade hämmande effekter på intestinal fibros.

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Immunologi och infektion TNBS-medierad intestinal fibros Crohns sjukdom inflammation rapamycin autofagi Resident macrophage genuttryck
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