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Journal / Cancer Research / 마우스 유방 상피 HC11 및 EpH4 세포의…
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JoVE Journal Cancer Research
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마우스 유방 상피 HC11 및 EpH4 세포의 분화

Article DOI: 10.3791/60147-v • 09:32 min • February 27th, 2020
February 27th, 2020 •
*1,2, *1, *1,3, 1,4, 1, 1, 2, 1
1Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Medicine, Queen's University, Kingston, 2Department of Chemical and Physical Sciences, University of Toronto, Mississauga, 3Department of Laboratory Medicine, Brampton Civic Hospital Campus, William Osler Health System, 4Latner Thoracic Surgery Research Laboratories
* These authors contributed equally

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우리는 2개의 유방 상피 선, HC11 및 EpH4의 분화 유도를 위한 기술을 기술합니다. 둘 다 우유 단백질을 생성하기 위하여 태아 송아지 송아지 혈청, 인슐린 및 prolactin를 요구하는 동안, EpH4 세포는 3 차원 문화에서 유방구로 완전히 분화할 수 있습니다. 이러한 상보적인 모델은 분화 및 신생물의 신호 환전 연구에 유용하다.

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암 연구 문제 156 세포 분화 유방 상피 세포 prolactin EHS 매트릭스
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