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Journal / Neuroscience / Abbiategrasso Brain Bank protokoll för att samla…
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Neuroscience

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JoVE Journal Neuroscience
Abbiategrasso Brain Bank protokoll för att samla in, bearbetning och karaktärisera åldrande hjärnor
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Abbiategrasso Brain Bank protokoll för att samla in, bearbetning och karaktärisera åldrande hjärnor

Article DOI: 10.3791/60296-v • 12:28 min • June 3rd, 2020
June 3rd, 2020 •
*1,4, *1, 1, 2, 1, 1, 1,4, 3, 3, 3, 5, 2,6, 7, 5, 8, 1,2,3
1Department of Neurology and Neuropathology, Golgi-Cenci Foundation, 2Laboratory of Neurobiology and Neurogenetic, Golgi-Cenci Foundation, 3Department of Neuropsychology and Social Sciences, Golgi-Cenci Foundation, 4Department of Rehabilitation, ASP Golgi-Redaelli Geriatric Hospital, 5Genomic and Post-Genomic Center, IRCCS Mondino Foundation, 6Department of Brain and Behavioral Sciences, University of Pavia, 7Department of Pathology, ASP Golgi-Redaelli Geriatric Hospital, 8Department of Neurological Science, IRCCS Mondino Foundation, University of Pavia
* These authors contributed equally

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Detta protokoll beskriver en metod för att spåra enskilda hjärnan-åldrande banor genom en hjärna donation program och korrekt karakterisering av hjärnor. Brain givare är involverade i en långsiktig longitudinell studie inklusive seriella flerdimensionella bedömningar. Protokollet innehåller en detaljerad beskrivning av hjärnans bearbetning och en korrekt diagnostisk metodik.

Tags

Neurovetenskap Brain Bank neuropatologi åldrande äldreomsorg longitudinell kohortstudie hjärndonation hjärnsorsektionsprotokoll QEEG clinico-patologisk korrelation omics
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