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DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Article DOI: 10.3791/60313-v • 08:59 min • September 27th, 2019
September 27th, 2019 •
1, 1, 1, 1,2, 3, 1,4, 1,4
1Biohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 2University of Jyväskylä, Nanoscience Center, Department of Biological and Environmental Science, University of Jyväskylä, 3University of Jyväskylä, Nanoscience Center, Department of Physics, University of Jyväskylä, 4HYBER Center of Excellence, Department of Applied Physics, Aalto University

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Here, we describe a protocol to create discrete and accurate inorganic nanostructures on substrates using DNA origami shapes as guiding templates. The method is demonstrated by creating plasmonic gold bowtie-shaped antennas on a transparent substrate (sapphire).

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DNA Origami Substrate Nanopatterning Inorganic Structures Sensing Applications Bottom-up Approach Top-down Nanofabrication Feature Sizes Parallel Fabrication Accurate Nanostructures Expensive Patterning Methods Surface Enhanced Raman Spectroscopy Optical Metasurfaces Disciplinary Fabrication Skills Visual Demonstration Petteri Piskunen Sofia Julin Grad Student Staple Strands Oligonucleotides M13 MP18 Scaffold Strand Folding Buffer Thermocycler Substrate Preparation Sapphire Wafer
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