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Journal / Cancer Research / 比较在小鼠肾脏和鸡胆膜上建立的转移性透明细胞肾细胞癌模型…
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Cancer Research
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比较在小鼠肾脏和鸡胆膜上建立的转移性透明细胞肾细胞癌模型
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比较在小鼠肾脏和鸡胆膜上建立的转移性透明细胞肾细胞癌模型

Article DOI: 10.3791/60314-v • 05:36 min • February 8th, 2020
February 8th, 2020 •
*1, *1, 2, 3, 4, 5, 6, 7, 1, 1,8
1Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, 2Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 3Department of Bioengineering, Hanyang University, 4Department of Ecology and Evolutionary Biology, University of California, Los Angeles, 5Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, 6School of Life Sciences, Beijing Normal University, 7Department of Urology, West China Hospital, Sichuan University, 8Department of Urology, David Geffen School of Medicine, University of California, Los Angeles
* These authors contributed equally

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转移性透明细胞肾细胞癌是一种没有全面动物模型进行彻底临床前调查的疾病。该协议说明了该病的两种新型动物模型：正位植入小鼠模型和鸡胆膜模型，这两种模型都显示了类似临床病例的肺转移。

Tags

癌症研究， 问题 156， 肾细胞癌， 转移， 动物模型， 肾脏植入， CAM， VHL基因删除， 肿瘤内异质性
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