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JoVE Journal Neuroscience
Stereologische schatting van cholinerge vezel lengte in de kern Basalis van Meynert van de muis hersenen
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Stereologische schatting van cholinerge vezel lengte in de kern Basalis van Meynert van de muis hersenen

Article DOI: 10.3791/60405-v • 09:15 min • February 5th, 2020
February 5th, 2020 •
1, 1, 1,2,3,4
1Laboratory for Alzheimer's Disease and Aging Research, Kansas City Veterans Affairs Medical Center, 2Department of Neurology, University of Kansas Medical Center, 3Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 4The University of Kansas Alzheimer's Disease Center

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Neuronale vezel lengte binnen een driedimensionale structuur van een hersengebied is een betrouwbare parameter om specifieke neuronale structurele integriteit of degeneratie te kwantificeren. Dit artikel beschrijft een stereologische kwantificeringsmethode om cholinerge vezellengte binnen de kernbasisvan Meynert bij muizen als voorbeeld te meten.

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Neurowetenschappen Kwestie 156 choline acetyltransferase (ChAT) kernbasisalis van Meynert (NBM) immunohistochemie (IHC) stereologie vezellengte ruimtebal
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