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Journal / Genetics / 利用染色质配置的计算分析，将阿尔茨海默氏病变异体映射到其目标基因…
JoVE Journal
Genetics

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JoVE Journal Genetics
利用染色质配置的计算分析，将阿尔茨海默氏病变异体映射到其目标基因
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利用染色质配置的计算分析，将阿尔茨海默氏病变异体映射到其目标基因

Article DOI: 10.3791/60428-v • 04:41 min • January 9th, 2020
January 9th, 2020 •
1,2, 3, *3,4, *1,2
1Department of Genetics, University of North Carolina, 2Neuroscience Center, University of North Carolina, 3Thurston Arthritis Research Center, University of North Carolina, 4Department of Cell Biology and Physiology, University of North Carolina
* These authors contributed equally

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我们提出了一个协议，用于识别使用三维染色质相互作用的全基因组关联研究（GWAS）识别的非编码变异的功能影响。

Tags

遗传学， 问题 155， Hi-C， GWAS， 非编码变异， 基因映射， 功能基因组学， 阿尔茨海默氏病
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