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Journal / Genetics / Kartlegging Alzheimers sykdom varianter til deres …
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Genetics

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JoVE Journal Genetics
Kartlegging Alzheimers sykdom varianter til deres mål gener bruke beregningsorientert analyse av Kromatin Configuration
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Kartlegging Alzheimers sykdom varianter til deres mål gener bruke beregningsorientert analyse av Kromatin Configuration

Article DOI: 10.3791/60428-v • 04:41 min • January 9th, 2020
January 9th, 2020 •
1,2, 3, *3,4, *1,2
1Department of Genetics, University of North Carolina, 2Neuroscience Center, University of North Carolina, 3Thurston Arthritis Research Center, University of North Carolina, 4Department of Cell Biology and Physiology, University of North Carolina
* These authors contributed equally

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Vi presenterer en protokoll for å identifisere funksjonelle implikasjoner av ikke-koding varianter identifisert av Genova-brede foreningen studier (GWAS) ved hjelp av tredimensjonale kromatin interaksjoner.

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Genetikk Hi-C GWAS ikke-koding varianter gen kartlegging funksjonell Genomics Alzheimers sykdom
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