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Journal / Bioengineering / Bioink de matriz extracelular derivada del tejido …
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JoVE Journal Bioengineering
Bioink de matriz extracelular derivada del tejido pancreático para imprimir construcciones de tejido pancreático laden de células 3D
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Bioink de matriz extracelular derivada del tejido pancreático para imprimir construcciones de tejido pancreático laden de células 3D

Article DOI: 10.3791/60434-v • 07:55 min • December 13th, 2019
December 13th, 2019 •
*1, *2, 2, 3, 3,4, 1,2,5
1Department of Mechanical Engineering, Pohang University of Science and Technology, 2School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 3Asan Institute for Life Science, University of Ulsan College of Medicine and Asan Medical Center, 4Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, 5Department of Creative IT Engineering, Pohang University of Science and Technology
* These authors contributed equally

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La matriz extracelular descelularizada (dECM) puede proporcionar señales microambientales adecuadas para recapitular las funciones inherentes de los tejidos diana en una construcción diseñada. Este artículo aclara los protocolos para la descelularización del tejido pancreático, la evaluación del bioink dECM derivado del tejido pancreático y la generación de construcciones de tejido pancreático 3D utilizando una técnica de bioimpresión.

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