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Journal / Cancer Research / Kemisk induceret Hudcarcinogenese model ved brug…
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Cancer Research

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JoVE Journal Cancer Research
Kemisk induceret Hudcarcinogenese model ved brug af Dimethylbenz [a] anthracen og 12-O-Tetradecanoyl Phorbols-13-acetat (DMBA-TPA)
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Kemisk induceret Hudcarcinogenese model ved brug af Dimethylbenz [a] anthracen og 12-O-Tetradecanoyl Phorbols-13-acetat (DMBA-TPA)

Article DOI: 10.3791/60445-v • 04:12 min • December 19th, 2019
December 19th, 2019 •
*1, *1, 1,2, 1,2, 1
1Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 2Department of Clinical Microbiology, Fimlab Laboratories
* These authors contributed equally

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To-trins hudcarcinogenese induceres af to topisk anvendte kemikalier. En mutagen 7, 12-dimethylbenz [a] anthracen) forårsager mutationer i Epidermal celler og en kontinuerlig anvendelse af generelle vækst stimulator 12-O-tetradecanoyl phorbols-13-acetat accelererer huden papilloma dannelse.

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Kræftforskning hudkræft kemisk carcinogenese mutagent promotor DMBA-TPA papilloma angiogenese betændelse tumor proliferation
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