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JoVE Journal Cancer Research
Chemisch-geïnduceerde huid carcinogenese model met behulp van Dimethylbenz [a] anthraceen en 12-O-Tetradecanoyl Phorbol-13-acetaat (DMBA-TPA)
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Chemisch-geïnduceerde huid carcinogenese model met behulp van Dimethylbenz [a] anthraceen en 12-O-Tetradecanoyl Phorbol-13-acetaat (DMBA-TPA)

Article DOI: 10.3791/60445-v • 04:12 min • December 19th, 2019
December 19th, 2019 •
*1, *1, 1,2, 1,2, 1
1Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 2Department of Clinical Microbiology, Fimlab Laboratories
* These authors contributed equally

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Tweetraps huid carcinogenese wordt geïnduceerd door twee topisch toegepaste chemicaliën. Een mutagene stof 7, 12-dimethylbenz [a] anthraceen) veroorzaakt mutaties in de epidermale cellen en een continue toepassing van de algemene groeistimulator 12-O-tetradecanoyl phorbol-13-acetaat versnelt de vorming van papillomavirus.

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Kankeronderzoek probleem 154 huidkanker chemische carcinogenese mutageen promotor DMBA-TPA papilloma angiogenese ontsteking tumor proliferatie
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