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Journal / Cancer Research / 디메틸벤드[a]안트라세네 및 12-O-테트레이드카노일…
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Cancer Research

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JoVE Journal Cancer Research
디메틸벤드[a]안트라세네 및 12-O-테트레이드카노일 포르볼-13-아세테이트(DMBA-TPA)를 이용한 화학적 유발 피부 발암 모델
Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment
Journal (Cancer Research)
Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment
Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
Journal (Cancer Research)
Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
 
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디메틸벤드[a]안트라세네 및 12-O-테트레이드카노일 포르볼-13-아세테이트(DMBA-TPA)를 이용한 화학적 유발 피부 발암 모델

Article DOI: 10.3791/60445-v • 04:12 min • December 19th, 2019
December 19th, 2019 •
*1, *1, 1,2, 1,2, 1
1Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 2Department of Clinical Microbiology, Fimlab Laboratories
* These authors contributed equally

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2 단계 피부 발암은 2개의 국소 적용된 화학제품에 의해 유도됩니다. 돌연변이 원 7,12-디메틸벤젠[a]anthracene)은 표피 세포의 돌연변이를 일으키고 일반적인 성장 자극기 12-O-tetradecanoyl phorbol-13-아세테이트의 지속적인 적용은 피부 유두종 형성을 가속화합니다.

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암 연구 문제 154 피부암 화학 발암 돌연변이 원 운동 DMBA-TPA 유두종 혈관 신생 염증 종양 증식
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