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Journal / Biochemistry / En integreret Raman spektroskopi og…
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Biochemistry

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JoVE Journal Biochemistry
En integreret Raman spektroskopi og massespektrometri platform til at studere enkelt-celle stof optagelse, metabolisme, og effekter
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En integreret Raman spektroskopi og massespektrometri platform til at studere enkelt-celle stof optagelse, metabolisme, og effekter

Article DOI: 10.3791/60449-v • 07:37 min • January 9th, 2020
January 9th, 2020 •
1,2, 1,2, 1
1Biodynamics Research Center (BDR), RIKEN, 2Research Center, Misr International University

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Denne protokol præsenterer en integreret Raman spektroskopi-Mass massespektrometri (MS) platform, der er i stand til at opnå en enkelt celle opløsning. Raman spektroskopi kan bruges til at studere cellulære respons på lægemidler, mens MS kan bruges til målrettet og kvantitativ analyse af stof optagelse og metabolisme.

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Biokemi enkelt celle analyse Raman spektroskopi massespektrometri Drug Discovery Tamoxifen nanospray ionisering
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