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JoVE Journal Neuroscience
Kwantitatieve meting van Intrathecaal gesynthetiseerde eiwitten bij muizen
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Kwantitatieve meting van Intrathecaal gesynthetiseerde eiwitten bij muizen

Article DOI: 10.3791/60495-v • 08:23 min • November 29th, 2019
November 29th, 2019 •
1, 1,2, 1,2, 1, 1, 1
1Department of Neurology, Geisel School of Medicine & Dartmouth-Hitchcock Medical Center, 2Program in Experimental and Molecular Medicine, Dartmouth College

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Verhoogde ruggenmergvloeistof eiwit niveaus kunnen ofwel het resultaat van diffusie van plasma eiwit over een veranderde bloed-hersen barrière of intrathecale synthese. Een geoptimaliseerd testprotocol wordt in dit artikel gepresenteerd dat helpt om beide gevallen te discrimineren en kwantitatieve metingen van intrathecaal gesynthetiseerde eiwitten verschaft.

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Neuroscience probleem 153 intrathecale synthese cerebrospinale vloeistof bloed-hersen barrière albumine quotiënten eiwit index eiwit transudaat
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