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Journal / Immunology and Infection / En Vivo Aumento de la Inducción de Células T…
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Immunology and Infection

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En Vivo Aumento de la Inducción de Células T Regulatorias Gut-Homing
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En Vivo Aumento de la Inducción de Células T Regulatorias Gut-Homing

Article DOI: 10.3791/60585-v • 08:02 min • January 22nd, 2020
January 22nd, 2020 •
1,2, 1, 1, 1,3,4, 1,3
1Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 2Zhengzhou University, 3Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, 4Jinan Infectious Disease Hospital, Shandong University

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Aquí presentamos un protocolo para el aumento in vivo de la inducción de células T reguladoras intestinales. En este protocolo, las células dendríticas están diseñadas para producir localmente altas concentraciones de la vitamina D activa (1,25-dihidroxivitamina D o 1,25[OH]2D) y la vitamina A activa (ácido retinoico o RA) de novo.

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Inmunología e infección número 155 células T reguladoras intestinales 25-hidroxivitamina D 1o-hidroxilasa citocromo P450 familia 27 subfamilia Miembro B 1 1,25-dihidroxivitamina D foxp3 células dendríticas retinaldehído deshidrogenasa 2 receptor de quimioquina c-c tipo 9
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