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Journal / Immunology and Infection / In vivo styrking av gut-homing regulatoriske T…
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Immunology and Infection

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In vivo styrking av gut-homing regulatoriske T Cell induksjon
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In vivo styrking av gut-homing regulatoriske T Cell induksjon

Article DOI: 10.3791/60585-v • 08:02 min • January 22nd, 2020
January 22nd, 2020 •
1,2, 1, 1, 1,3,4, 1,3
1Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 2Zhengzhou University, 3Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, 4Jinan Infectious Disease Hospital, Shandong University

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Her presenterer vi en protokoll for in vivo styrking av gut-homing regulatoriske T celle induksjon. I denne protokollen, dendrittiske celler er konstruert for å lokalt produsere høye konsentrasjoner av den aktive vitamin D (1, 25-dihydroxyvitamin D eller 1, 25 [OH]2D) og den aktive vitamin A (retinoic syre eller ra) de Novo.

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Immunologi og infeksjon gut-homing regulatoriske T-celler 25-hydroksyvitamin D 1 α-hydroksylase cytokrom P450 familie 27 gruppe B-medlem 1 1 25-dihydroxyvitamin D foxp3 dendrittiske celler retinaldehyde dehydrogenase 2 c-c chemokine reseptor type 9
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