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Journal / Chemistry / 18 av år F-merking av Radiotracers…
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JoVE Journal Chemistry
18 av år F-merking av Radiotracers Funksjonalisert med en Silicon fluor Acceptor (SiFA) for positron utslipp tomografi
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18 av år F-merking av Radiotracers Funksjonalisert med en Silicon fluor Acceptor (SiFA) for positron utslipp tomografi

Article DOI: 10.3791/60623-v • 09:57 min • January 11th, 2020
January 11th, 2020 •
*1, *1, 2,3, 2,3, 4, 5, 1, 1, 1
1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University
* These authors contributed equally

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Syntesen av fluor-18 (18F) merket radiofarmaka for positron utslipps tomografi krever vanligvis måneders erfaring. Når innlemmet i en radiotracer, det Silicon-fluor Acceptor (SiFA) motiv setter i stand til en enkel 18F-merking protokollen det er selvstendig av kostbar utstyret og forberedende lærer opp, stund slankende forløper antallet behøvde og bruker mildere reaksjonen vilkårene.

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Kjemi 18F-radiolabeling radiotracer in vivo Imaging positron utslipp TOMOGRAFI (pet) fluor-18 silisium-fluor Acceptor (SiFA)
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