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Journal / Chemistry / 18 F-märkning av Radiotracers funktionaliserade…
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18 F-märkning av Radiotracers funktionaliserade med en kisel fluorid acceptor (SiFA) för positron emissions tomografi
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18 F-märkning av Radiotracers funktionaliserade med en kisel fluorid acceptor (SiFA) för positron emissions tomografi

Article DOI: 10.3791/60623-v • 09:57 min • January 11th, 2020
January 11th, 2020 •
*1, *1, 2,3, 2,3, 4, 5, 1, 1, 1
1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University
* These authors contributed equally

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Syntesen av fluor-18 (18F) märkt radiofarmaka för positron emissions tomografi kräver vanligtvis månader av erfarenhet. När den införlivas i en radiotracer, silikon-fluorid acceptor (SiFA) motiv möjliggör en enkel 18F-märkning protokoll som är oberoende av dyr utrustning och förberedande utbildning, samtidigt minska prekursorer mängd som behövs och utnyttja mildare reaktions förhållanden.

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Kemi utgåva 155 18F-radiolabeling radiotracer in vivo Imaging positron emissions TOMOGRAFI (PET) fluor-18 kisel-fluorid acceptor (Sifa)
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