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Journal / Chemistry / 18.000 Pozitron Emisyon Tomografisi Için Silikon…
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Chemistry
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JoVE Journal Chemistry
18.000 Pozitron Emisyon Tomografisi Için Silikon Florür Alıcı (SiFA) ile İşlevselleştirilmiş Radyotracerlerin F-Etiketlemesi
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18.000 Pozitron Emisyon Tomografisi Için Silikon Florür Alıcı (SiFA) ile İşlevselleştirilmiş Radyotracerlerin F-Etiketlemesi

Article DOI: 10.3791/60623-v • 09:57 min • January 11th, 2020
January 11th, 2020 •
*1, *1, 2,3, 2,3, 4, 5, 1, 1, 1
1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University
* These authors contributed equally

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Pozitron emisyon tomografisi için flor-18(18F) etiketli radyofarmasötiklerin sentezi genellikle aylar süren bir deneyim gerektirir. Bir radyotracer içine dahil edildiğinde, silikon-florür alıcı (SiFA) motifi, pahalı ekipman ve hazırlık eğitimi bağımsız basit bir 18F-labeling protokolü sağlar, gerekli öncül miktarını azaltırken ve hafif reaksiyon koşulları kullanırken.

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Kimya Sayı 155 18F-radyolabeling radyotracer in vivo görüntüleme pozitron emisyon tomografisi (PET) flor-18 silikon-florür alıcı (SiFA)
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