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Journal / Genetics / A Pathway Association Study Tool for GWAS…
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Genetics

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JoVE Journal Genetics
A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
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A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

Article DOI: 10.3791/61268-v • 05:01 min • July 1st, 2020
July 1st, 2020 •
1, 2
1Institute for Genomics, Biocomputing & Biotechnology, Mississippi State University, 2Corn Host Plant Resistance Research Unit, USDA-ARS

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Summary
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By running the Pathway Association Study Tool (PAST), either through the Shiny application or through the R console, researchers can gain a deeper understanding of the biological meaning of their genome-wide association study (GWAS) results by investigating the metabolic pathways involved.

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GWAS Analysis Metabolic Pathway PAST Genes Phenotypes Association File Effects File Linkage Disequilibrium Data SNPs General Feature Format Annotations Window Size R Squared Cutoff Pathways File
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