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Journal / Bioengineering / Self-Assembly of Gamma-Modified Peptide Nucleic…
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JoVE Journal Bioengineering
Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
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Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

Article DOI: 10.3791/61351-v • 08:15 min • June 26th, 2020
June 26th, 2020 •
1, 1, 1,2,3
1Department of Mechanical Engineering, Carnegie Mellon University, 2Department of Biomedical Engineering, Carnegie Mellon University, 3Department of Electrical and Computer Engineering, Carnegie Mellon University

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Summary
Automatic Translation

This article provides protocols for the design and self-assembly of nanostructures from gamma-modified peptide nucleic acid oligomers in organic solvent mixtures.

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Self-Assembly Gamma-Modified Peptide Nucleic Acids Nanostructures Organic Solvent Mixtures Synthetic Nucleic Acid Mimic Gamma PNA Assays Nucleic Acid Nanotechnology Protocols Aqueous-rich Environments Organic Solvent-rich Environments Nanomaterial PNA HPLC Grade Purified Gamma PNA Strands Deionized Water Anneal Batch Samples DMSO DMF 1,4-dioxane
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