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Find video protocols related to scientific articles indexed in Pubmed.
Critical perspectives on nursing as bodywork.
ANS Adv Nurs Sci
PUBLISHED: 05-03-2014
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Nursing is grounded in care of the body. This article examines nursing as bodywork, as experienced intersubjectively by nurses together with patients and collectively as a body within the health care labor force. The relation of nurses to the body generates conflicting and contradictory social meanings from intimate and sacred work to dirty work. Such meanings have contributed to stigmatizing the work and the worker within the labor force as well contributing to an ongoing stratification in the labor force as nurses have shifted bodywork "to lower level" or ancillary workers.
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Ca(2+) clearance mechanisms in cancer cell lines and stromal cells of the prostate.
Prostate
PUBLISHED: 06-20-2013
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Three prostatic cell lines, PC3, LNCaP, and DU 145, are used as established models to study cell signaling in prostate cancer. Recently, stromal cell lines of the prostate, such as P21, were also introduced. Here we investigate a basic and important mechanism of living cells: Ca(2+) homeostasis in PC3, DU 145, and P21.
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FDG-PET and diffusion-weighted MRI in head-and-neck cancer patients: implications for dose painting.
Radiother Oncol
PUBLISHED: 01-06-2013
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The purpose of this study was to investigate if FDG-PET and DWI identify the same or different targets for dose escalation in the GTV of HN cancer patients. Additionally, the dose coverage of DWI-targets in an FDG-PET-based dose painting plan was analyzed.
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Direct frequency-comb spectroscopy of a dipole-forbidden clock transition in trapped 40Ca+ ions.
Opt Lett
PUBLISHED: 01-07-2011
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We demonstrate direct frequency-comb (FC) spectroscopy of the dipole-forbidden 4s(2)S(1/2)-3d(2)D(5/2) transition in trapped (40)Ca(+) ions using an unamplified FC laser. The excitation is detected with nearly 100% efficiency using a shelving scheme in combination with single-ion imaging. The method demonstrated here has the potential to reach hertz-level accuracy, if a hertz-level linewidth FC is used in combination with confinement in the Lamb-Dicke regime.
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Pre-treatment with ?-hederin increases ?-adrenoceptor mediated relaxation of airway smooth muscle.
Phytomedicine
PUBLISHED: 03-10-2010
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Preparations of ivy leaves dry extract with secretolytic and bronchiolytic efficacy are widely used for the treatment of acute and chronic obstructive airway diseases. The mechanism by which ivy preparations improve lung functions is not fully understood. Here, we tested the influence of the three main saponins of ivy, ?-hederin, hederacoside C and hederagenin, on the contraction and relaxation behaviour of isolated bovine tracheal smooth muscle strips by isometric tension measurements. None of the tested compounds altered histamine or methacholine-induced contraction of the smooth muscle strips. In contrast, the isoprenaline-induced relaxation of 100?M methacholine precontracted muscle strips was significantly enhanced when pre-treated with 1?M of ?-hederin for 18h. The pre-treatment with hederacoside C or hederagenin had no effect on isoprenaline-induced relaxation. For the first time the bronchiolytic effect of ?-hederin was demonstrated by isometric tension measurements using bovine tracheal smooth muscle strips. ?-Hederin increases isoprenaline-induced relaxation indirectly, probably by inhibiting heterologous desensitization induced by high concentrations of muscarinic ligands like methacholine.
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Impact of waist circumference difference on health-care cost among overweight and obese subjects: the PROCEED cohort.
Value Health
PUBLISHED: 01-26-2010
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To estimate the incremental effect of waist circumference (WC) on health-care costs among overweight and obese subjects after adjusting for body mass index (BMI).
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Obesity prevention: recommended strategies and challenges.
Am. J. Med.
PUBLISHED: 05-05-2009
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Lifelong healthy weight maintenance is an important goal for all Americans to avoid the health problems associated with excessive body weight. In those who are overweight, even modest weight loss can reduce the risk of developing diseases associated with obesity. Federal health agencies, including the Centers for Disease Control and Prevention and the US Department of Agriculture, have recognized the critical nature of the obesity epidemic and the importance of lifelong weight management. As a result, these agencies have published evidence-based dietary and exercise recommendations, as well as analyses of population-based efforts to achieve weight loss that specifically address strategies to maintain a healthy weight. Despite the availability of recommendations and increased public education efforts, however, obesity rates continue to climb. The rising prevalence of obesity in the United States suggests that current efforts to control weight have been inadequate. Large-scale prevention programs that involve interventions targeting individuals as well as the larger community, including initiatives spearheaded through workplaces and schools, are needed to control weight and reduce the risk of long-term health consequences.
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Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors.
Biochemistry
PUBLISHED: 03-13-2009
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Hederacoside C, alpha-hederin, and hederagenin are saponins of dry extracts obtained from the leaves of ivy (Hedera helix L.). Internalization of beta(2)-adrenergic receptor-GFP fusion proteins after stimulation with 1 microM terbutaline was inhibited by preincubation of stably transfected HEK293 cells with 1 microM alpha-hederin for 24 h, whereas neither hederacoside C nor hederagenin (1 microM each) influenced this receptor regulation. After incubation of A549 cells with 5 nM Alexa532-NA, two different diffusion time constants were found for beta(2)AR-Alexa532-NA complexes by fluorescence correlation spectroscopy. Evaluation of the autocorrelation curve revealed diffusion time constants: tau(bound1) = 1.4 +/- 1.1 ms (n = 6) found for receptor-ligand complexes with unrestricted lateral mobility, and tau(bound2) = 34.7 +/- 14.1 ms (n = 6) for receptor-ligand complexes with hindered mobility. The distribution of diffusion time constants was 24.3 +/- 2.5% for tau(bound1) and 8.7 +/- 4.3% for tau(bound2) (n = 6). A549 cells pretreated with 1 microM alpha-hederin for 24 h showed dose-dependent alterations in this distribution with 37.1 +/- 5.5% for tau(bound1) and 4.1 +/- 1.1% for tau(bound2). Simultaneously, the level of Alexa532-NA binding was significantly increased from 33.0 +/- 6.8 to 41.2 +/- 4.6%. In saturation experiments, alpha-hederin did not influence the beta(2)-adrenergic receptor density (B(max)), whereas the K(D) value for Alexa532-NA binding decreased from 36.1 +/- 9.2 to 24.3 +/- 11.1 nM. Pretreatment of HASM cells with alpha-hederin (1 microM, 24 h) revealed an increased intracellular cAMP level of 13.5 +/- 7.0% under stimulating conditions. Remarkably, structure-related saponins like hederacoside C and hederagenin did not influence either the binding behavior of beta(2)AR or the intracellular cAMP level.
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Impact of lifestyle intervention on lost productivity and disability: improving control with activity and nutrition.
J. Occup. Environ. Med.
PUBLISHED: 02-12-2009
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To evaluate the effectiveness of a lifestyle intervention (LI) in reducing work loss and disability days.
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Gastrointestinal complications after 3 months of dual antiplatelet therapy for drug-eluting stents as assessed by wireless capsule endoscopy.
Clin. Appl. Thromb. Hemost.
PUBLISHED: 01-02-2009
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Little is known about the frequency of symptomatic and asymptomatic gastrointestinal complications of dual antiplatelet therapy. We recruited 30 patients between 18 and 80 years who were started on aspirin and clopidogrel following percutaneous coronary intervention with drug-eluting stents. We hypothesized that the 3 months of dual antiplatelet therapy would be associated with frequent upper gastrointestinal endoscopic abnormalities. Patients were followed with weekly phone calls to inquire about the new gastrointestinal symptoms and after a minimum of 80 days, their upper gastrointestinal mucosa was visualized with PillCam ESO wireless capsule endoscopy. 18 (90%) of the 20 successful wireless capsule endoscopies revealed at least 1 type of gastrointestinal mucosal lesion. Gastric erosions (n = 14, 70%) were the most common abnormality. We believe this is the first noninvasive endoscopic study of gastrointestinal complications of dual antiplatelet therapy in patients who undergo percutaneous coronary intervention with drug-eluting stents. Future studies should expand on our observations to determine whether prophylaxis with proton pump inhibitors is warranted.
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Food-package assignments and breastfeeding initiation before and after a change in the Special Supplemental Nutrition Program for Women, Infants, and Children.
Am. J. Clin. Nutr.
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In 2009, the USDA implemented an interim rule that changed the prescribed foods in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). Options for mother and infant dyads include a full breastfeeding package with no infant formula, a partial breastfeeding package with some infant formula, and a full formula package with a smaller postpartum food package for the mother. The changes were designed to encourage WIC mothers to choose breastfeeding for their infants.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.