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Find video protocols related to scientific articles indexed in Pubmed.
Circulating undercarboxylated osteocalcin and gingival crevicular fluid tumour necrosis factor-? in children.
J. Clin. Periodontol.
PUBLISHED: 01-18-2014
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Osteocalcin, a protein secreted by osteoblasts during bone formation, is negatively associated with adult periodontal disease. Little is known about this association in children.
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Metabolic syndrome and gingival inflammation in Caucasian children with a family history of obesity.
J. Clin. Periodontol.
PUBLISHED: 07-12-2013
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To investigate whether metabolic syndrome (MetS) and its components are associated with gingival inflammation in children.
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Tumor necrosis factor- ? and interleukin-6: potential interorgan inflammatory mediators contributing to destructive periodontal disease in obesity or metabolic syndrome.
Mediators Inflamm.
PUBLISHED: 04-23-2013
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Obesity has become a worldwide health burden in the last two decades. Obesity has been associated with increased comorbidities, such as coronary artery disease, diabetes, and destructive periodontal disease. Obesity is also part of a group of risk factors occurring together in an individual, which is referred to as metabolic syndrome. Clinical studies have shown higher risk for destructive periodontal disease in obesity and metabolic syndrome. However, the role of obesity and metabolic syndrome in the onset and development of destructive periodontal disease has not yet been fully understood. In this review, we discuss a working model, which focuses on interorgan inflammation as a common etiological factor for destructive periodontal disease associated with obesity and metabolic syndrome. Specifically, we suggest that elevated levels of tumor necrosis factor- ? (TNF- ? ) or interleukin 6 (IL-6)--both adipokines and known risk factors for destructive periodontal disease--in obesity and metabolic syndrome contribute to the onset and development of destructive periodontal disease. The connections between destructive periodontal disease and systemic conditions, such as obesity or metabolic syndrome, are complex and potentially multidirectional. This review largely focuses on TNF- ? and IL-6, inflammatory mediators, as potential common risk factors and does not exclude other biological mechanisms.
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Body mass index, lifetime smoking intensity and lung cancer risk.
Int. J. Cancer
PUBLISHED: 03-20-2013
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There is as yet no generally accepted explanation for the common finding that low body mass index (BMI) is associated with an increased risk of lung cancer. We investigated this association in a Canadian population-based case-control study (1996-2002) with a particular view to assessing the hypothesis that the observed association was due to residual confounding by smoking. Analyses were based on 1,076 cases and 1,439 controls who provided their height at enrollment and their weight at two points in time, at age 20 and 2 years before enrollment. BMI, in kg/m(2) , was classified into underweight (<18.5), normal (18.5-24.9), overweight (25.0-29.9), and obese (?30). Smoking history was synthesized into a comprehensive smoking index (CSI) that integrated duration, intensity and time since quitting. Odds ratios (ORs) and 95% confidence intervals (CIs) for BMI-lung cancer associations were estimated, adjusting for CSI as well as several sociodemographic, lifestyle and occupational factors. The normal BMI category was used as the reference. Among those who were underweight at age 20, there was a lower risk of lung cancer (OR?=?0.69, 95% CI: 0.50-0.95). Conversely, lung cancer risk was increased among those who were underweight 2 years before enrollment (OR?=?2.30, 95% CI: 1.30-4.10). The results were almost identical when stratifying analyses based on smoking history into never/lighter and heavier smokers. The inverse association between recent BMI and lung cancer is unlikely to be largely attributable to residual confounding by smoking. Reverse causality or a true relationship between BMI and lung cancer remain plausible.
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Brazilian dental students intentions and motivations towards their professional career.
J Dent Educ
PUBLISHED: 03-15-2013
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Investigating career motivations and intentions of dental students provides a better understanding of their role in society and contributes to the debate on dental education and practices. This study describes the profile, career choice motivations, and career intentions of Brazilian dental students and evaluates factors related to these choices. A cross-sectional study was carried out among dental students from three Brazilian public universities (N=915), with a response rate of 83.7 percent. Students (N=766) responded to a self-administered questionnaire about sociodemographic factors, reasons for choosing dentistry as a career, and future career intentions. Job conception was found to be the main reason for choosing dentistry as a profession. Most students intended to become specialists and work in both the public and private sectors simultaneously. Female students (OR 2.23, 95 percent CI=1.62-3.08), low-income students (OR 1.86, 95 percent CI=1.10-3.13), and students beginning their program (OR 1.87, 95 percent CI=1.22-2.85) were more likely to work in the public and private sectors simultaneously than other types of students. This study suggests that choice of career and career plans are influenced by factors related to the students characteristics and their conception of the profession. The opportunity to combine private and public dental practice may be viewed as a way to achieve income and job security.
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Association between lean and fat mass and indicators of bone health in prepubertal caucasian children.
Horm Res Paediatr
PUBLISHED: 02-12-2013
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Childhood and adolescence are critical periods for bone growth. The independent association between lean and fat mass and indicators of bone health in children is not yet known. We aim to examine the association between each of lean and fat mass and indicators of bone health in 8- to 10-year-old prepubertal Caucasian children.
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There is no difference with regard to hard and/or soft tissue safety between oscillating-rotating powered brushes and manual toothbrushes.
J Evid Based Dent Pract
PUBLISHED: 11-15-2011
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Safety of oscillating-rotating powered brushes compared to manual toothbrushes: a systematic review. Van der Weijden FA, Campbell SL, Dörfer CE, González-Cabezas C, Slot DE. J Periodontol 2011;82(1):5-24.
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Generic microtiter plate assay for triaging clinical specimens prior to genotyping of human papillomavirus DNA via consensus PCR.
J. Clin. Microbiol.
PUBLISHED: 09-21-2011
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A generic human papillomavirus (HPV) probe assay was compared to the Linear Array to detect HPV DNA in 1,013 clinical specimens. The sensitivity, specificity, and negative predictive value of the assay were 99.5% (95% confidence interval [CI], 98.4% to 99.9%), 58.6% (95% CI, 53.9% to 63.1%), and 98.9% (95% CI, 96.5% to 99.8%), respectively. This assay conveniently identifies HPV-positive specimens.
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Associations between school deprivation indices and oral health status.
Community Dent Oral Epidemiol
PUBLISHED: 11-20-2010
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Despite an overall improvement in oral health status in several countries over the past decades, chronic oral diseases (COD) remain a public health problem, occurring mostly among children in the lower social strata. The use of publicly available indicators at the school level may be an optimal strategy to identify children at high risk of COD in order to organize oral health promotion and intervention in schools.
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Adiposity and gingival crevicular fluid tumour necrosis factor-alpha levels in children.
J. Clin. Periodontol.
PUBLISHED: 03-11-2009
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To investigate whether adiposity is associated with gingival crevicular fluid (GCF) tumour necrosis factor-alpha (TNF-alpha) levels in children. We also examined whether this relationship is mediated through plasma fasting insulin.
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How will a life course framework be used to tackle wider social determinants of health?
Community Dent Oral Epidemiol
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The life course framework, proposed by Kuh and Schlomo in 1997, offers policy makers the means to understand the interaction between nature and nurture. This conceptual model illustrates how an individuals biological resources are influenced by their genetic endowment, their prenatal and postnatal development and their social and physical environment, both in early life and throughout the life course. Health is conceptualized as a dynamic process connecting biological and social elements that are affected by previous experiences and by present circumstances. Therefore, exposure at different stages of peoples lives can either enhance or deplete the individuals health resources. Indeed, life course processes are of many kinds, including parent-child relationships, levels of social deprivation, the acquisition of emotional and behavioural assets in adolescence and the long-term effects of occupational hazards and work stress. The long-term effects of nature and nurture combine to influence disease outcomes. It is only in the last decade that theories, methods and new data have begun to be amalgamated, allowing us to further our understanding of health over the life course in ways that may eventually lead to more effective health policies and better health care. This article discusses life course concepts and how this framework can enlighten our understanding of wider social determinants of health, and provides a few examples of potential interventions to tackle their impact on health.
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Life course experiences and lay diagnosis explain low-income parents child dental decisions: a qualitative study.
Community Dent Oral Epidemiol
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OBJECTIVE: This study aimed to better understand low-income parents child dental care decisions through a life course approach that captured parents experiences within the social context of poverty. METHODS: We conducted 43 qualitative life history interviews with 10 parents, who were long-term social assistance recipients living in Montreal, Canada. Thematic analysis involved interview debriefing, transcript coding, theme identification and data interpretation. RESULTS: Our interviews identified two emergent themes: lay diagnosis and parental oral health management. Parents described a process of lay diagnosis that consisted of examining their childrens teeth and interpreting their childrens oral signs and symptoms based on their observations. These lay diagnoses were also shaped by their own dental crises, care experiences and oral health knowledge gained across a life course of poverty and dental disadvantage. Parents management strategies included monitoring and managing their childrens oral health themselves or by seeking professional recourse. Parents management strategies were influenced both by their lay diagnoses and their perceived ability to manage their childrens oral health. Parents felt responsible for their childrens dental care, empowered to manage their oral health and sometimes forgo dental visits for their children because of their own self-management life history. CONCLUSION: This original approach revealed insights that help to understand why low-income parents may underutilize free dental services. Further research should consider how dental programs can nurture parental empowerment and capitalize on parents perceived ability to diagnose and manage their childrens oral health.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.