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Find video protocols related to scientific articles indexed in Pubmed.
The dietary n6:n3 fatty acid ratio during pregnancy is inversely associated with child neurodevelopment in the EDEN mother-child cohort.
J. Nutr.
PUBLISHED: 07-31-2013
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Long-chain polyunsaturated fatty acids (LC-PUFAs) of the n6 (?6) and n3 series are essential for the development of a childs brain. Fetal LC-PUFA exposure as well as infant exposure via breast milk depend on the maternal intake of these LC-PUFAs and of their respective dietary precursors (PUFAs). We aimed to investigate the associations between maternal LC-PUFA and PUFA [(LC)PUFA] dietary intake during pregnancy and child neurodevelopment at ages 2 and 3 y. In 1335 mother-child pairs from the EDEN cohort, we evaluated associations between daily maternal (LC)PUFA intake during the last 3 months of pregnancy with the childs language at age 2 y and with different assessments of development at age 3 y. Associations were investigated separately in breastfed and never-breastfed children. We examined interactions between the ratios of n6 and n3 (LC)PUFA intakes (n6:n3 fatty acid ratio) and duration of breastfeeding. Breastfeeding mothers had a lower n6:n3 fatty acid ratio (8.4 vs. 8.8; P = 0.02). Among never-breastfed children (n = 338), we found negative associations between maternal dietary n6:n3 fatty acid ratios and neurodevelopment, as reflected by the childs language at age 2 y (? ± SE = -2.1 ± 0.7; P = 0.001) and development assessed with the Ages and Stages Questionnaire at age 3 y (-1.5 ± 0.8; P = 0.05). Among mothers with a high n6:n3 fatty acid ratio only, breastfeeding duration was positively associated with language at age 2 y (P-interaction < 0.05). This suggests that the ratio between maternal dietary n6 and n3 (LC)PUFA intake possibly influences the childs brain development during fetal life but not during or by breastfeeding. However, breastfeeding might compensate for prenatal imbalance in maternal dietary n6:n3 fatty acid ratio.
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The influence of early feeding practices on fruit and vegetable intake among preschool children in 4 European birth cohorts.
Am. J. Clin. Nutr.
PUBLISHED: 07-17-2013
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Fruit and vegetable intake in children remains below recommendations in many countries. The long-term effects of early parental feeding practices on fruit and vegetable intake are not clearly established.
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Childhood and adult secondhand smoke and type 2 diabetes in women.
Diabetes Care
PUBLISHED: 06-11-2013
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The objective of this study was to evaluate the relationship between childhood and adult secondhand smoke and type 2 diabetes.
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Breastfeeding duration and cognitive development at 2 and 3 years of age in the EDEN mother-child cohort.
J. Pediatr.
PUBLISHED: 01-11-2013
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To investigate the dose-response relationship between breastfeeding duration and cognitive development in French preschool children.
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Processed and unprocessed red meat consumption and incident type 2 diabetes among French women.
Diabetes Care
PUBLISHED: 11-18-2011
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To evaluate the relation of processed and unprocessed red meat and incident type 2 diabetes.
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Validity of a short questionnaire to assess physical activity in 10 European countries.
Eur. J. Epidemiol.
PUBLISHED: 08-16-2011
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To accurately examine associations of physical activity (PA) with disease outcomes, a valid method of assessing free-living activity is required. We examined the validity of a brief PA questionnaire (PAQ) used in the European Prospective Investigation into Cancer and Nutrition (EPIC). PA energy expenditure (PAEE) and time spent in moderate and vigorous physical activity (MVPA) was measured in 1,941 healthy individuals from 10 European countries using individually-calibrated combined heart-rate and movement sensing. Participants also completed the short EPIC-PAQ, which refers to past years activity. Pearson (r) and Spearman (?) correlation coefficients were calculated for each country, and random effects meta-analysis was used to calculate the combined correlation across countries to estimate the validity of two previously- and one newly-derived ordered, categorical PA indices ("Cambridge index", "total PA index", and "recreational index") that categorized individuals as inactive, moderately inactive, moderately active, or active. The strongest associations with PAEE and MVPA were observed for the Cambridge index (r = 0.33 and r = 0.25, respectively). No significant heterogeneity by country was observed for this index (I(2) = 36.3%, P = 0.12; I(2) = 0.0%, P = 0.85), whereas heterogeneity was suggested for other indices (I(2) > 48%, P < 0.05, I(2) > 47%, P < 0.05). PAEE increased linearly across self-reported PA categories (P for trend <0.001), with an average difference of approximately 460 kJ/d for men and 365 kJ/d for women, between categories of the Cambridge index. The EPIC-PAQ is suitable for categorizing European men and women into four distinct categories of overall physical activity. The difference in PAEE between categories may be useful when estimating effect sizes from observational research.
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Maternal depression, socioeconomic position, and temperament in early childhood: the EDEN Mother-Child Cohort.
J Affect Disord
PUBLISHED: 07-24-2011
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Children of mothers who experience depression in pregnancy may be at high risk of emotional disturbances; however heterogeneity in risk suggests that other factors could play a moderating role. We test the hypothesis that children growing up in families characterised by both maternal depression and socioeconomic disadvantage are especially likely to have temperamental difficulties.
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Latent variables and structural equation models for longitudinal relationships: an illustration in nutritional epidemiology.
BMC Med Res Methodol
PUBLISHED: 04-30-2010
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The use of structural equation modeling and latent variables remains uncommon in epidemiology despite its potential usefulness. The latter was illustrated by studying cross-sectional and longitudinal relationships between eating behavior and adiposity, using four different indicators of fat mass.
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Differential effects of coffee on the risk of type 2 diabetes according to meal consumption in a French cohort of women: the E3N/EPIC cohort study.
Am. J. Clin. Nutr.
PUBLISHED: 02-10-2010
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Coffee consumption has been associated with a lower risk of diabetes, but little is known about the mechanisms responsible for this association, especially related to the time when coffee is consumed.
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Birth weight, body silhouette over the life course, and incident diabetes in 91,453 middle-aged women from the French Etude Epidemiologique de Femmes de la Mutuelle Generale de lEducation Nationale (E3N) Cohort.
Diabetes Care
PUBLISHED: 11-16-2009
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Obesity and increases in body weight in adults are considered to be among the most important risk factors for type 2 diabetes. Low birth weight is also associated with a higher diabetes incidence. We aimed to examine to what extent the evolution of body shape, from childhood to adulthood, is related to incident diabetes in late adulthood.
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Maternal fatty acid intake and fetal growth: evidence for an association in overweight women. The EDEN mother-child cohort (study of pre- and early postnatal determinants of the childs development and health).
Br. J. Nutr.
PUBLISHED: 09-18-2009
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Recent studies suggest a benefit of seafood and n-3 fatty acid intake on fetal growth and infant development. The objective was to study the association between fatty acid intake and fetal growth in pregnant French women. Pregnant women included in the EDEN mother-child cohort study completed FFQ on their usual diet: (1) in the year before pregnancy and (2) during the last 3 months of pregnancy (n 1439). Conversion into nutrient intakes was performed using data on portion size and a French food composition table. Associations between maternal fatty acid intakes and several neonatal anthropometric measurements were studied using linear regressions adjusted for centre, mothers age, smoking habits, height, parity, gestational age and newborns sex. Due to significant interaction, analyses were stratified according to maternal pre-pregnancy overweight status. Neither total lipid nor SFA, MUFA or PUFA intake was significantly associated with newborn size. In overweight women only (n 366), a high pre-pregnancy n-3 fatty acid intake (% PUFA) was positively associated with the newborns birth weight (P=0.01), head, arm and wrist circumferences and sum of skinfolds (P<0.04). A substitution of 1% of n-3 fatty acids per d before pregnancy by other PUFA was related to an average decrease in birth weight of 60 g (P=0.01). Relationships with n-3 fatty acid intake at the end of pregnancy were weaker and not significant. We concluded that a high pre-pregnancy n-3 fatty acid:PUFA ratio may sustain fetal growth in overweight women. Follow-up of the children may help determine whether this has beneficial consequences for the childs health and development.
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Parental feeding practices in the United States and in France: relationships with childs characteristics and parents eating behavior.
J Am Diet Assoc
PUBLISHED: 05-26-2009
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Given the role of parental feeding practices in establishing childrens eating habits, understanding sources of individual differences in feeding practices is important. This study examined the role of several psychological variables (ie, parental perceived responsibility for childs eating, parental perceptions of the childs weight, and parents own eating patterns) in individual differences in a variety of feeding practices. Parents of preschool-aged children completed surveys in a cross-sectional study. Two cultural contexts (ie, United States, n=97 parents; and France, n=122 parents) were included to assess the cross-cultural generalizability of the findings. Monitoring was associated with parental perceived responsibility for childs eating, parental restrained eating, and parents desire for their child to be thinner, especially in France. Restriction for weight reasons was more prevalent in France and was associated with parents perceived responsibility for childs eating, perception of childs body weight, and parental restrained eating. Parental use of foods for nonnutritive purposes was more prevalent in the United States and was associated with parental uncontrolled or emotional eating. Finally, parents perceived responsibility for childs eating was strongly related to child control over feeding, teaching about nutrition, encouragement of balance, and variety and modeling. These associations between psychological variables and parental feeding practices shed light on the sources of individual differences in feeding practices and suggest possible opportunities for intervention when feeding practices are suboptimal.
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The association between diet and serum concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in the European Prospective Investigation into Cancer and Nutrition.
Cancer Epidemiol. Biomarkers Prev.
PUBLISHED: 05-09-2009
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Circulating concentrations of insulin-like growth factor I (IGF-I) and IGF binding proteins (IGFBP) have been associated with the risk of several types of cancer. Dietary correlates of IGF-I and IGFBPs are not yet well established. The objective of this study was to assess the association between dietary intake and serum concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in a cross-sectional analysis of 4,731 men and women taking part in the European Prospective Investigation into Cancer and Nutrition. Diet was assessed using country-specific validated dietary questionnaires. Serum concentrations of IGF-I, IGFBP-1, IGFBP-2 and IGFBP-3 were measured, and the associations between diet and IGF-I and IGFBPs were assessed using multiple linear regression adjusting for sex, age, body mass index, smoking status, and alcohol and energy intake. Each 1 SD increment increase in total and dairy protein and calcium intake was associated with an increase in IGF-I concentration of 2.5%, 2.4%, and 3.3%, respectively (P for trend <0.001 for all) and a decrease in IGFBP-2 of 3.5%, 3.5%, and 5.4% (P for trend <0.001 for all), respectively. There were no significant associations between the intake of protein or calcium from nondairy sources and IGF-I. The results from this large cross-sectional analysis show that either the intake of dairy protein or calcium is an important dietary determinant of IGF-I and IGFBP-2 concentrations; however, we suggest that it is more likely to be protein from dairy products.
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Cognitive restraint, uncontrolled eating and emotional eating: correlations between parent and adolescent.
Matern Child Nutr
PUBLISHED: 03-19-2009
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The purpose of this study was to examine, in a general population, the resemblance in eating behaviour between adolescents and their parents. This study was based on the first examination of a community-based epidemiological study in Northern France. Subjects were offspring aged 14-22 years (135 boys and 125 girls) and their parents (174 fathers and 205 mothers). The Three-Factor Eating Questionnaire Revised 18-item version (TFEQ-R18) identified three aspects of eating behaviour: cognitive restraint of eating, uncontrolled eating and emotional eating. Familial resemblance in eating behaviour was measured by partial Spearmans correlations, adjusted for age and body mass index. Sons uncontrolled eating was positively related to fathers cognitive restraint of eating (r = 0.36), but not to fathers uncontrolled eating (r = 0.07), nor to mothers eating behaviour. Sons cognitive restraint of eating was related to no parental eating behaviour scores. In daughters, cognitive restraint of eating was positively related to mothers uncontrolled eating (r = 0.26), but not to mothers cognitive restraint of eating (r = 0.13). Daughters uncontrolled eating and emotional eating were positively associated with the same scores in mothers. Finally, daughters eating behaviour was not related to fathers eating behaviour. In conclusion, correlations in eating behaviour were higher with the parent of the same gender, and eating behaviours in adolescents seem to reflect opposition to parents behaviour more than familial resemblance.
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Child and parent characteristics related to parental feeding practices. A cross-cultural examination in the US and France.
Appetite
PUBLISHED: 02-24-2009
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Although cross-cultural research between France and the United States has contributed to our understanding of adult eating habits, no research to date has considered differences in the way that French and American parents feed their children. American mothers (n=59) and fathers (n=38) and French mothers (n=72) and fathers (n=50) provided information about the feeding practices that they use with their children. U.S. parents reported higher levels of non-nutritive feeding practices and child control over feeding, whereas French parents reported greater monitoring and restriction of their childs food intake for weight reasons. Feeding practices were linked to child Body Mass Index (BMI) in both socio-cultural contexts.
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Association between maternal seafood consumption before pregnancy and fetal growth: evidence for an association in overweight women. The EDEN mother-child cohort.
Paediatr Perinat Epidemiol
PUBLISHED: 02-21-2009
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Studies in countries with high seafood consumption have shown a benefit on fetal growth and child development. The objective of our study was to determine the association between seafood consumption in French pregnant women and fetal growth. Pregnant women included in the EDEN mother-child cohort study completed two food frequency questionnaires on their usual diet in the year before and during the last 3 months of pregnancy (n = 1805). Fetal circumferences were measured by ultrasound and anthropometry at birth. Variables were compared across tertiles of the mothers seafood consumption using multiple linear regression to adjust for confounding variables. Analyses were stratified by maternal overweight status because of an interaction between maternal seafood consumption and her body mass index (P < 0.01). There was no association between seafood intake and fetal growth in the whole sample of women. For overweight women (n = 464), higher consumption of seafood before pregnancy was associated with higher fetal biparietal and abdominal circumferences and anthropometric measures. From the lowest to the highest tertiles, mean birthweight was 167 g higher (P = 0.002). No significant association was found with consumption at the end of pregnancy. In conclusion, high seafood consumption before pregnancy is positively associated with fetal growth in overweight women.
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A review of methods to assess parental feeding practices and preschool childrens eating behavior: the need for further development of tools.
J Acad Nutr Diet
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We reviewed tools developed to measure parental feeding practices and eating behavior and food intake or preferences of children aged 0 to 5 years. Two electronic literature databases (Medline and Psycinfo) were used to search for both observational and experimental studies in human beings. The articles selected for review were those presenting tools with data on internal consistency and/or test-retest reliability and/or construct validity. A total of 3,445 articles were retrieved, and further searching of reference lists and contact with experts produced an additional 18 articles. We identified three tools on the qualitative dimension of childrens eating behavior, two tools on food intake or preferences, and one tool on parental feeding practices with rigorous testing of internal consistency, construct validity, and test-retest reliability. All other tools presented in this review need further evaluation of their validity or reliability. Because major gaps exist, we highlight the need for more tools on parental attention to childrens hunger and satiety cues, and the need to evaluate the degree of control allowed to children younger than age 2 years in feeding events. Food avoidance (ie, behaviors or strategies to take away and to reject food) and food approach (ie, attractiveness for food stimuli) have not been assessed in children aged 12 to 24 months. Food preference tests based on sensory aspects rather than nutritional quality may be worth investigating. We identified a need for further evaluation of quality, especially test-retest reliability and construct validity, for most tools developed for use in studying children aged 0 to 5 years.
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Lower educational level is a predictor of incident type 2 diabetes in European countries: the EPIC-InterAct study.
Int J Epidemiol
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Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide. In high-income countries, low socioeconomic status seems to be related to a high incidence of T2DM, but very little is known about the intermediate factors of this relationship. Method We performed a case-cohort study in eight Western European countries nested in the EPIC study (n = 340, 234, 3.99 million person-years of follow-up). A random sub-cohort of 16,835 individuals and a total of 12,403 incident cases of T2DM were identified. Crude and multivariate-adjusted hazard ratios (HR) were estimated for each country and pooled across countries using meta-analytical methods. Age-, gender- and country-specific relative indices of inequality (RII) were used as the measure of educational level and RII tertiles were analysed.
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Determinants of infant formula use and relation with growth in the first 4 months.
Matern Child Nutr
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The wide variety of infant formula available on the market can be confusing for parents and physicians. We aimed to determine associations between predominant type of formula used from birth to 4 months and parental and child characteristics and type of physician consulted, and then to describe relations between type of formula used and growth. Our analyses included 1349 infants from the EDEN mother-child cohort. Infants feeding mode and type of formula used were assessed at 4 months by maternal self-report. Infants weight and height from birth to 4 months, measured in routine follow-up, were documented by health professionals in the infants personal health record. Anthropometric z-scores were calculated by using World Health Organization growth standards. Multinomial logistic regression was used to identify factors associated with the type of formula predominantly used; relations with growth were analysed by linear regressions. Partially hydrolysed formulas were more likely to be used by primiparous women (P??0.20). Infants breastfed shorter showed higher weight-for-age (P?
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Breastfeeding and infant temperament at age three months.
PLoS ONE
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To examine the relationship between breastfeeding and maternally-rated infant temperament at age 3 months, 316 infants in the prospective Cambridge Baby Growth Study, UK had infant temperament assessed at age 3 months by mothers using the Revised Infant Behavior Questionnaire, which produces scores for three main dimensions of temperament derived from 14 subscales. Infant temperament scores were related to mode of infant milk feeding at age 3 months (breast only; formula milk only; or mixed) with adjustment for infants age at assessment and an index of deprivation.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

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We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

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In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.