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Find video protocols related to scientific articles indexed in Pubmed.
Open-globe injuries at an emergency department in Porto, Portugal: clinical features and prognostic factors.
Eur J Ophthalmol
PUBLISHED: 10-13-2014
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To describe the epidemiology, characteristics, surgical management, functional outcome, and prognostic factors of open-globe injuries requiring surgical treatment.
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EVALUATION OF VISUAL ACUITY, MACULAR STATUS, AND SUBFOVEAL CHOROIDAL THICKNESS CHANGES AFTER CATARACT SURGERY IN EYES WITH DIABETIC RETINOPATHY.
Retina (Philadelphia, Pa.)
PUBLISHED: 08-12-2014
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Progression of diabetic macular edema has been reported as a common cause of poor visual acuity recovery after cataract surgery in patients with diabetes. Despite being responsible for the blood supply to the outer retina, the role of the choroidal layer in the pathogenesis of diabetic retinopathy (DR) is not yet understood. Our objective is to characterize macular and subfoveal choroidal thickness changes after cataract surgery in eyes with DR.
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Pseudoexfoliation material on posterior chamber intraocular lenses.
Clin Ophthalmol
PUBLISHED: 08-11-2014
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The presence of pseudoexfoliation material on the surface of an intraocular lens (IOL) is a rare finding. We report a series of seven cases with different patterns of pseudoexfoliation material deposition on the posterior chamber IOLs, recognized 2-20 years after cataract surgery. Six patients had an IOL implanted in the capsular bag and one in the ciliary sulcus. Two patients had undergone posterior capsulotomy. Although the pathophysiological mechanisms and clinical significance of this finding remain unknown, the careful follow-up of pseudophakic patients with known or suspected pseudoexfoliation syndrome is essential to monitor the development or progression of glaucoma, since deposition of pseudoexfoliation material continues even after cataract surgery.
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Acute transient myopia with shallowing of the anterior chamber induced by sulfamethoxazole in a patient with pseudoxanthoma elasticum.
J. Glaucoma
PUBLISHED: 07-31-2014
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To report a case of acute transient myopia with anterior chamber shallowing induced by sulfamethoxazole in a patient with pseudoxanthoma elasticum (PXE).
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Graded müllerectomy for correction of graves upper eyelid retraction: effect on eyelid movements.
Ophthal Plast Reconstr Surg
PUBLISHED: 04-30-2014
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To measure the effect of müllerectomy from posterior approach on the amplitudes of spontaneous blinking and downward eyelid saccades.
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Switch from intravitreal ranibizumab to bevacizumab for the treatment of neovascular age-related macular degeneration: clinical comparison.
Ophthalmologica
PUBLISHED: 04-26-2014
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To compare outcomes after switching from intravitreal ranibizumab to bevacizumab in neovascular age-related macular degeneration (AMD).
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[Evaluation of antiangiogenic treatment results in choroidal neovascularization related to pathological myopia].
Acta Med Port
PUBLISHED: 02-28-2014
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Choroidal neovascularization secondary to pathological myopia is one of the leading causes of irreversible central vision loss in younger patients. The purposes of our study is to evaluate the long-term results of antiangiogenic treatment, with ranibizumab and/or bevacizumab, in myopic choroidal neovascularization and define the predictive factors for visual and anatomic outcomes.
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Determination of the minimum effective volume of 0.5% bupivacaine for ultrasound-guided axillary brachial plexus block.
Braz J Anesthesiol
PUBLISHED: 02-26-2014
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The use of ultrasound for needle correct placement and local anesthetic spread monitoring helped to reduce the volume of local anesthetic required for peripheral nerve blocks. There are few studies of the minimum effective volume of local anesthetic for axillary brachial plexus block. The aim of this study was to determine the minimum effective volume (VE90) of 0.5% bupivacaine with epinephrine (1:200,000) for ultrasound guided ABPB.
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Intravenous clonidine administration and its ability to reduce pulmonary arterial pressure in patients undergoing heart surgery.
Braz J Anesthesiol
PUBLISHED: 02-26-2014
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Evaluate the ability of clonidine to reduce pulmonary arterial pressure in patients with pulmonary hypertension undergoing heart surgery, either by reducing the pressure values from the direct measurement of pulmonary arterial pressure or by reducing or eliminating the need for intraoperative dobutamine and nitroprusside.
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Preoperative evaluation of the patient with pulmonary disease.
Braz J Anesthesiol
PUBLISHED: 02-26-2014
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In daily clinical practice, pulmonary complications related to surgical procedure are common, increasing the morbidity and mortality of patients. Assessment of the risk of pulmonary complications is an important step in the preoperative evaluation. Thus, we review the most relevant aspects of preoperative assessment of the patient with lung disease.
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Study of biomolecular and clinical prognostic factors in patients with cancer of the vulva undergoing surgical treatment.
Int. J. Gynecol. Cancer
PUBLISHED: 02-21-2014
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Cancers of the vulva account for 3% to 5% of all cancers of the female genital. This study was conducted to evaluate clinical, pathological, and molecular prognostic factors in patients with cancer of the vulva.
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Transfusional profile in different types of intensive care units.
Braz J Anesthesiol
PUBLISHED: 02-14-2014
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anemia is a common clinical finding in intensive care units. The red blood cell transfusion is the main form of treatment, despite the associated risks. Thus, we proposed to evaluate the profile of transfusional patients in different intensive care units.
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Anti-VEGF therapy in myopic choroidal neovascularization: long-term results.
Ophthalmologica
PUBLISHED: 02-01-2014
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To evaluate the medium- and long-term efficacy of anti-VEGF agents in the treatment of choroidal neovascularization secondary to pathologic myopia (mCNV).
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Primary Biliary Cirrhosis and Primary Sjögren's Syndrome: Insights for the Stomatologist.
Case Rep Gastroenterol
PUBLISHED: 01-01-2014
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Primary biliary cirrhosis (PBC) is a chronic progressive autoimmune disease characterized by portal inflammation and immune-mediated destruction of the intrahepatic bile ducts. Primary Sjögren's syndrome is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands, mainly the lachrymal and salivary glands, in the absence of other definitively diagnosed rheumatologic disease. We report a diagnosed case of primary Sjögren's syndrome associated with PBC. A 59-year-old Caucasian woman went to oral evaluation reporting dry mouth, difficulty in eating associated with burning mouth syndrome, dysgeusia and dysphagia. Intraoral examination revealed extensive cervical caries, gingivitis, gingival retraction, angular cheilitis and atrophic tongue. Hyposalivation was detected by salivary flow and Schirmer's test was positive. Antinuclear and antimitochondrial antibodies were both positive. Anti-Ro/SSA and anti-La/SSB antibodies were negative. A minor salivary gland biopsy of the lower lip was performed. Histopathologic analysis revealed lymphocytic infiltrate with destruction of salivary gland architecture in some areas and replacement of glandular tissues by mononuclear cells. Optimal management of PBC associated with Sjögren's syndrome requires a multidisciplinary approach as the key to optimal patient care. Dental practitioners should be able to recognize the clinical features of this associated condition. Appropriate dental care may prevent tooth decay, periodontal disease and oral infections as well as improve the patient's quality of life.
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Immediate effect of intravitreal injection of bevacizumab on intraocular pressure.
Clin Ophthalmol
PUBLISHED: 01-01-2014
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To investigate the immediate effect of intravitreal injection of bevacizumab on intraocular pressure (IOP).
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Choroidal and macular thickness changes induced by cataract surgery.
Clin Ophthalmol
PUBLISHED: 12-16-2013
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The aim of this study was to evaluate the effect of uneventful phacoemulsification on the morphology and thickness of the macula, the submacular choroid, and the peripapillary choroid.
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Laser therapy in the control of oral mucositis: a meta-analysis.
Rev Assoc Med Bras
PUBLISHED: 03-13-2013
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To conduct a systematic review and meta-analysis of the effectiveness of Laser Therapy in the prevention of oral mucositis (OM) in patients undergoing oncotherapy.
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Multimodal imaging of acquired vitelliform lesion diagnosed at pseudohypopyon stage.
Case Rep Ophthalmol Med
PUBLISHED: 03-12-2013
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Purpose. To present a case study of a monocular acquired vitelliform lesion, studied with multimodal fundus imaging (spectral-domain-optical coherence tomography, fundus autofluorescence, and fluorescein angiography) with a followup of three years. Case Report. An asymptomatic macular lesion was detected on a 64-year-old man. Fundus exam revealed a macular lesion with an apparent horizontal level associated with multiple round small whitish lesions, suggestive of cuticular drusen. He was studied with autofluorescence of the fundus (FAF), fluorescein angiography (FA), spectral domain-optical coherence tomography (SD-OCT), and electrooculogram. The findings were compatible with the diagnosis of acquired vitelliform lesion, associated with cuticular drusen. After one year, the visual acuity decreased to 20/50, without identifiable alterations of the FAF, FA, or SD-OCT. Three years later, fundoscopy and imaging showed an evolution to a state similar to vitelli disruptive phase of Best disease with an improvement of visual acuity to 20/25. We report the results of FAF, FA, and SD-OCT at this stage. Conclusion. Acquired vitelliform lesions associated with cuticular drusen can present as a pseudohypopyon lesion, and the evolution to the atrophic phase can be associated with an improvement of visual acuity.
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Optical Coherence Tomography Study of Peripapillary Retinal Nerve Fiber Layer and Choroidal Thickness in Eyes With Tilted Optic Disc.
J. Glaucoma
PUBLISHED: 02-23-2013
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PURPOSE:: The tilted optic disc is associated with peripapillary choroidal and retinal nerve fiber layer (RNFL) changes as well as visual field defects, often leading to diagnostic difficulties due to similarities with glaucomatous discs. We studied the peripapillary RNFL of the tilted optic disc by comparing values obtained with spectral-domain (SD) and time-domain (TD) optical coherence tomography (OCT) in order to identify characteristic RNFL patterns verified by both OCT devices, and also to determine whether SD-OCT offers any diagnostic advantage over TD-OCT. METHODS:: Prospective case-control study of 16 individuals with tilted optic discs (27 eyes) and an age-matched control group (10 individuals, 20 eyes). Each case was subjected to ophthalmological examination and automated perimetry. Tilt orientation was classified based on observation of optic disc photographs, and angle of disc torsion was calculated with image processing software. RNFL measurements were obtained with TD-OCT and SD-OCT. Peripapillary choroid thickness was measured with SD-OCT. The findings were related with optic disc morphology and automated perimetry results. RESULTS:: Stratus OCT results showed significantly lower superior RNFL (P<0.001) on the tilted group, whereas Spectralis indicated significantly lower superotemporal (P<0.001), superonasal (P=0.001), temporal (P=0.01), and global (P=0.01) RNFL on the tilted disc group. A significant correspondence was found between elevated disc rim and location of RNFL defect on the Spectralis (P=0.004). On the tilted group, peripapillary choroidal thickness was significantly thicker adjacent to the elevated rim (P<0.001). No correspondence was found between tilt orientation, peripapillary RNFL, or choroidal thickness and location of perimetric defects. CONCLUSIONS:: Our results provide a clinical characterization of the main tilted disc morphologies and are valuable for correctly differentiating a tilted disc from a myopic glaucomatous disc. RNFL assessment by Spectralis OCT seems to be more susceptible to altered disc morphologies. The peripapillary RNFL changes found on titled disc cases could not predict the location of visual field defects.
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Vascular endothelial growth factor plasma levels before and after treatment of neovascular age-related macular degeneration with bevacizumab or ranibizumab.
Acta Ophthalmol
PUBLISHED: 09-29-2011
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To evaluate the changes of vascular endothelial growth factor (VEGF) plasma levels after intravitreal injections of ranibizumab or bevacizumab in patients with exudative age-related macular degeneration (AMD).
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Cupid fixation for repositioning subluxated intraocular lens.
J Cataract Refract Surg
PUBLISHED: 04-01-2011
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We describe the cupid fixation technique, which allows safe repositioning of a subluxated intraocular lens (IOL). Under subconjunctival anesthesia, the body of the subluxated IOL is perforated with a 10-0 polypropylene suture on a straight needle. The IOL is then centered and fixated at the sclera overlying the ciliary sulcus; the knot is tied beneath a previously created limbal intrascleral pocket. No intraoperative complications occurred in 24 cases in which the technique was performed, and successful IOL centration was achieved.
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What do patients know about the work of anesthesiologists?
Rev Bras Anestesiol
PUBLISHED: 02-03-2011
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Modern international studies portray the lack of knowledge of patients regarding the education and role of anesthesiologists. There are no current data on this subject in the national scenario. The objective of this study was to assess the level of knowledge of patients about the education and areas of performance of these specialists.
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Update on cardiopulmonary resuscitation guidelines of interest to anesthesiologists.
Rev Bras Anestesiol
PUBLISHED: 01-31-2011
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The new cardiopulmonary resuscitation (CPR) guidelines emphasize the importance of high-quality chest compressions and modify some routines. The objective of this report was to review the main changes in resuscitation practiced by anesthesiologists.
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Multiple effects of bevacizumab in angiogenesis: implications for its use in age-related macular degeneration.
Acta Ophthalmol
PUBLISHED: 11-07-2009
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This study aimed to elucidate the precise effects of bevacizumab in all steps in the neovascularization process in endothelial cells.
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Complete spontaneous posterior luxation of capsular bag-intraocular lens-capsular tension ring complex.
J Cataract Refract Surg
PUBLISHED: 03-28-2009
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We describe the case of a monocular 72-year-old man who presented with spontaneous acute visual decrease in the left eye 2 years after uneventful phacoemulsification with intraocular lens (IOL) and standard capsular tension ring (CTR) implantation. Dilated fundoscopy revealed aphakia and complete vitreous luxation of the entire capsular bag-IOL-CTR complex.
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Comparative effects of bevacizumab, ranibizumab and pegaptanib at intravitreal dose range on endothelial cells.
Exp. Eye Res.
PUBLISHED: 01-13-2009
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Anti-VEGF therapy proved to be useful against several ocular pathological situations, including choroidal neovascularization and proliferative retinopathies. Ranibizumab (Ran), Pegaptanib (Peg) and Bevacizumab (Bev) are the pharmacological agents more frequently used in clinical practice by intravitreal injection. However, their exact effects on the angiogenic process have not been accurately established in a comparative study. The aim of the present study was to elucidate the precise effects of Ran, Peg and Bev on the multiple steps of the angiogenic process. Human umbilical vein endothelial cells (HUVEC) were incubated with each agent within the clinically established concentration range, or identical amounts of the excipients; cell cytotoxicity, proliferation, apoptosis, migration and vessel assembly were assessed. No cytotoxic effects were found for any of the agents studied at any concentration tested. At the clinical dose, cell proliferation was significantly reduced by Bev and Ran, whereas no difference was observed after Peg treatment. In addition, HUVEC apoptosis was effectively increased by Bev and Ran. Cell migration was reduced after incubation with every agent analyzed, though only reaching statistical significance upon Ran intravitreal dose. At clinical doses, capillary assembly was only affected by Bev. In agreement with these data, the active form of VEGF receptor-2 expression was decreased after incubation with Bev (to 66% of control values), Ran (78%) and Peg (86%) relative to controls. These findings indicate that these three agents display distinct effects on endothelial cells.
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Severe ocular hypertension secondary to systemic corticosteroid treatment in a child with nephrotic syndrome.
Clin Ophthalmol
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To report a case of severe, acute ocular hypertension in a 6-year-old child, 7 days after initiating treatment with oral prednisolone, due to nephrotic syndrome.
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Comparative study of 1+PRN ranibizumab versus bevacizumab in the clinical setting.
Clin Ophthalmol
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We compared the efficacy of intravitreal ranibizumab and bevacizumab for treating neovascular age-related macular degeneration using an on-demand regimen.
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Isolated foveal hypoplasia: tomographic, angiographic and autofluorescence patterns.
Case Rep Ophthalmol Med
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Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchanged for years. Results. In the first case, spectral-domain optical coherence tomography (SD-OCT) showed reduced foveal pit and continuity of inner retinal layers in the fovea. Photoreceptor layer had a normal thickness centrally. The foveal avascular zone (FAZ) was absent in the flourescein angiogram (FA). Fundus autofluorescence showed reduced foveal attenuation of autofluorescence. In the second patient, there was the same pattern in SD-OCT, with normal aspect in FA and only a slightly reduced foveal attenuation of autofluorescence. Conclusion. OCT, as a noninvasive and quick method, is helpful in the diagnosis of foveal hypoplasia. FA and fundus autofluorescence were less sensitive.
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Spectral-domain optical coherence tomography of the choroid during valsalva maneuver.
Am. J. Ophthalmol.
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To evaluate the influence of Valsalva maneuver on the morphology and thickness of the choroid at the macular area.
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Combination of intravitreal ranibizumab and laser photocoagulation for aggressive posterior retinopathy of prematurity.
Case Rep Ophthalmol
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To report on 2 cases of aggressive posterior retinopathy of prematurity (ROP) treated with intravitreal ranibizumab (Lucentis(®)) and laser photocoagulation.
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Beauveria bassiana keratitis in bullous keratopathy: antifungal sensitivity testing and management.
Eur J Ophthalmol
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Beauveria bassiana is a ubiquitous fungus available as an insecticide. In humans, it has limited virulence; to our knowledge, only 3 cases of invasive disease and 10 cases of keratitis have been documented.
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POSSIBLE ROLE FOR FUNDUS AUTOFLUORESCENCE AS A PREDICTIVE FACTOR FOR VISUAL ACUITY RECOVERY AFTER EPIRETINAL MEMBRANE SURGERY.
Retina (Philadelphia, Pa.)
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To study the potential association between fundus autofluorescence, spectral-domain optical coherence tomography, and visual acuity in patients undergoing surgery because of epiretinal membranes.
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JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

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We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

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In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.