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Find video protocols related to scientific articles indexed in Pubmed.
Tumor volume change with stereotactic body radiotherapy (SBRT) for early-stage lung cancer: evaluating the potential for adaptive SBRT.
Am. J. Clin. Oncol.
PUBLISHED: 01-22-2015
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To quantify gross tumor volume (GTV) change during stereotactic body radiotherapy (SBRT) and on first follow-up, as well as to evaluate for any predictive prognostic risk factors related to GTV decrease. An attempt was also made to identify the potential timing for adaptive SBRT.
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A rare presentation of hepatitis a infection with extrahepatic manifestations.
Case Rep Gastrointest Med
PUBLISHED: 05-08-2014
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Hepatitis A has a variety of associated extrahepatic manifestations that clinicians should be aware of for early diagnosis and treatment. We report a unique case of hepatitis A presenting with multiple extrahepatic manifestations not previously described in a single patient. A 34-year-old male presented with sudden onset of left sided facial pain, swelling, and skin rash, with diffuse body pains and muscle weakness, and was found to be positive for hepatitis A immunoglobulin M (IgM). He was initially started on antibiotics for concerns of bacterial parotitis but did not show any improvement. A punch biopsy of his mandibular rash and swelling was done which showed lymphohistiocytic infiltration with a few eosinophils. A trial of prednisone resulted in improvement of his symptoms. Clinicians should be aware to look for hepatitis A infection in a patient with atypical clinical picture causing a widespread systemic inflammatory response. Treatment with prednisone may result in resolution.
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Bisphosphonate-related osteonecrosis of the jaw mimicking bone metastasis.
Case Rep Oncol Med
PUBLISHED: 01-30-2014
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Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of the jaw to prevent misdiagnosis and initiate proper treatment at the earliest. We present the case of a breast cancer patient with multiple bony metastases and a jaw lesion presumed to be metastases. After no response to palliative radiation, repeat radiological imaging studies revealed osteonecrosis of the jaw. Correlating a patient's clinical information with findings on diagnostic imaging studies, such as SPECT bone and CT scans, can help identify this potential complication of bisphosphonate treatment. Early diagnosis helps minimize unnecessary biopsies and allows for the proper treatment to be instituted.
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Impact of Transcutaneous Neuromuscular Electrical Stimulation on dysphagia in head and neck cancer patients treated with definitive chemoradiation.
Head Neck
PUBLISHED: 01-16-2014
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Purpose: To investigate the role of TNMES therapy in maintaining swallowing function during chemoradiation for locally advanced head and neck cancer. Methods: We retrospectively compared 43 consecutive patients with locally advanced head and neck cancer patients treated with TNMES (treatment group - TG) to 55 control patients (CG). Validated swallowing scale scores were assigned. Results: All patients swallowing scores declined post CT+RT. A difference in mean decline in scores for CG versus TG using Functional Oral Intake Scale (FOIS) was seen, favoring TNMES intervention (23% vs 7%, p=0.015). Age, race, >10 pack years smoking, diabetes, stage, nodal disease, accelerated fractionation, weight loss, dietary modification, no TNMES and RT dose as significant for poorer scores on the swallowing scales. Conclusions: TNMES should be considered an adjunct to dysphagia reduction and possible prevention in locally advanced head and neck cancer patients. Further studies should be conducted to define benefit of TNMES intervention. Head Neck, 2014.
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Role of nuclear medicine imaging in recognizing different causes of osteonecrosis of the jaw.
Clin Nucl Med
PUBLISHED: 05-23-2013
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The incidence of osteonecrosis of the jaw (ONJ) among patients with cancer and metastatic bone disease being treated with bisphosphonates is as high as 10%, which dictates that an understanding of the risk factors, preventative measures, means of early diagnosis, and treatment is critical. Despite ONJ occurring in the clinical setting of intravenous bisphosphonates, there are other causes associated with higher risk of ONJ, such as multiple dental extractions. Overall, it is important for imaging health care professionals to recognize, describe, and understand ONJ to help minimize biopsies and allow proper treatment to begin as soon as possible.
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The normal variant (18)F FDG uptake in the lower thoracic spinal cord segments in cancer patients without CNS malignancy.
Am J Nucl Med Mol Imaging
PUBLISHED: 01-01-2013
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Focal increased lower thoracic spinal cord (18)F FDG uptake is not infrequently observed as a normal physiological finding and may be confused for spinal cord metastases. This study was conducted to evaluate a possible correlation between the lower thoracic (T11-T12) spinal uptake and lower limb movements/ambulatory status of the patients as a surrogate. The primary endpoint was to identify the possible cause(s) of the normal variant focal increased thoracic spinal cord (T11-T12) (18)F FDG activity and correlate it with the lower limb movements/ambulatory status of the patients. This was a retrospective analysis of PET-CT scans of 200 patients with solid and hematological malignancies. The focal relatively increased (18)F FDG activity in the lower thoracic spinal cord correlated strongly with the (18)F FDG intensity of the liver, bowel, C3-C5 cervical cord activity, weight of the patient and injected dose of (18)F FDG. With regard to the primary endpoint, no significant correlation was found between the ambulatory status of patients in any of the groups and thoracic spine SUVmax. This could be further assessed by performing dual studies in the same patient with and without moderate to excessive leg motion. Identifying this variant focal increased (18)F FDG activity can minimize errors of misdiagnosis and unnecessary further investigation.
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Interfraction accumulation of seroma during accelerated partial breast irradiation: preliminary results of a prospective study.
Brachytherapy
PUBLISHED: 05-15-2011
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To quantify and characterize the process of seroma accumulation during accelerated partial breast irradiation using multicatheter balloon brachytherapy.
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Impact of interfraction seroma collection on breast brachytherapy dosimetry - a mathematical model.
J Contemp Brachytherapy
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Balloon brachytherapy is a widely accepted modality for delivery of accelerated partial breast irradiation (APBI). Our hypothesis was that inter-fraction seroma collection around the balloon surface would have an adverse effect on dosimetry of the target.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.