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Find video protocols related to scientific articles indexed in Pubmed.
Distinguishable Zn(II) and Pb(II) template effects on forming pendant-armed Schiff-base macrocyclic complexes including a remarkable Pb(II)-? macrocyclic complex.
Dalton Trans
PUBLISHED: 09-05-2014
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36-Membered [2 + 2] half-fold Schiff-base macrocyclic dinuclear Zn(II) complexes (1a and 1b) and 18-membered [1 + 1] Schiff-base macrocyclic mononuclear Pb(II) complexes (2 and 3) are produced from the condensation between 1,3-propanediamine and a pair of extended dialdehydes with different functional pendant arms (H2hpdd and H2pdd) because of the distinguishable cationic template effects. It is very interesting to mention that a unique intramolecular Pb(II)-? macrocyclic complex 2 with an uncommon ?(3)-coordination type is achieved under ambient conditions and it can remain stable both in the solid state and in solution. The subtle variations of pendant-arms in the macrocyclic ligands H2hpdd and H2pdd yield different Pb(II) complexes, where the competition between Pb(II)-? and Pb(II)-NO3(-) electrostatic interactions as well as the combination of steric and electronic effects of pendant arms are believed to play important roles.
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Dinuclear Cu(II) complexes based on two flexible Schiff-base ligands and one unusual in situ formed diphenolate 2,6-piperidin-4-one derivative.
Dalton Trans
PUBLISHED: 08-13-2014
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A dinuclear Cu(ii) complex [Cu2(L3)2]·2H2O, having an unprecedented in situ formed diphenolate 2,6-piperidin-4-one derived ligand produced from the flexible Schiff-base ligand HL1, can be yielded as a side product in the presence of Cu(OAc)2·H2O-NH3·H2O dissolved in methanol and acetone in addition to the expected dinuclear Cu(ii) complex [Cu2(L1)4].
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Quantification of metallothioneins in the earthworm by lomefloxacin-europium(iii) fluorescent probe.
Environ Sci Process Impacts
PUBLISHED: 06-14-2014
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A new fluorimetric method was established for the determination of trace amounts of metallothioneins (MT) in earthworm, using a lomefloxacin-europium(iii) (LMLX-Eu(3+)) complex as a fluorescent probe. In a pH 6.5 Tris-HCl buffer solution, MT can markedly decrease the fluorescence intensity of LMLX-Eu(3+) at ? = 613 nm, and the magnitude of the decrease in this intensity was in direct proportion to the concentration of MT. The linear range was 0.08-20 mg L(-1) with a detection limit of 0.022 mg L(-1), and the recovery was in the range of 91.9-104.4%. The results show that the fluorimetric method is relatively accurate and sensitive to measurements of concentration for MT over a wide range. This method has been successfully applied to the determination of the concentration of MT induced by heavy metal ions (Cd(2+), Pb(2+), Cu(2+), Zn(2+)) in Eisenia andrei. The amount of MT increased significantly in a dose-dependent manner to the heavy-metal exposure, and these proteins can be used as biomarkers to assess the impact of heavy-metal contamination in soils. The method offered high sensitivity as well as accuracy with simple instrumentation and is suitable for direct quantification of total MT in Eisenia andrei.
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Dipyrido[3,2-a:2,3-c]phenazine-Based Donor-Acceptor Aromatic Heterocyclic Compounds with Thienyl and Triphenylamino Chromophores at the 2,7- and/or 10,13-Positions.
Chem Asian J
PUBLISHED: 09-21-2013
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A series of T- and H-shaped donor-acceptor (D-A) types of dipyrido[3,2-a:2,3-c]phenazine (DPPZ)-based molecules, extended by thienyl and triphenylamino chromophores at the 2,7-(bottom) and/or 10,13-positions (top), have been designed and prepared successfully. Synthetic, structural, thermal, spectral, and computational comparisons have been carried out for related compounds because of their adjustable intramolecular charge-transfer properties. It is noted that a pair of structural isomers (5 and 6) has been obtained, respectively, where distinguishable UV/Vis and fluorescence spectra, electrochemical activity, thermal stability, and bandgaps are observed. Furthermore, compounds 6, 8, 10, 11, 13, and 15 exhibit excellent thermal stability, and the Td10 values for them are found to range from 524 to 646?°C, which can be regarded as one of the best groups of thermally stable compounds among organic small molecules. In addition, theoretical calculations were performed, and the structure-property relationships were examined to reveal the effects of the position and number of donor arms on the DPPZ acceptor core.
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Two pairs of 1 : 2 nickel(II) and copper(II) metal-complex dyes showing the same trans configuration and azo-hydrazone transformation but different thermal properties.
Dalton Trans
PUBLISHED: 03-30-2013
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Two pairs of 1: 2 neutral trans mononuclear transition-metal (M = Ni(II) and Cu(II)) complexes of pyridine-2,4-dione and quinoline-2,4-dione based heterocyclic dyes have been structurally and spectrally characterized and compared herein. X-ray single-crystal diffraction analyses of four complexes, namely trans-[Ni(La)2(DMF)2] (1), trans-[Cu(La)2(DMF)2] (2), trans-[Ni(Lb)2(DMF)2] (3) and trans-[Cu(Lb)2(DMF)2] (4), reveal that they have the same trans configuration between the bidentate chelating dianionic ligands and two axially coordinated DMF molecules. Furthermore, a transformation from the hydrazone to azo configuration has been observed for both bidentate chelating ligands La(-) and Lb(-) after metal-ion complexation. More importantly, the simultaneous DSC/TG-MS-FTIR method has been used to explore the thermal stability of four neutral metal-complex dyes 1-4, where the two axially coordinated DMF molecules in Ni(II) and Cu(II) complexes exhibit distinguishable decomposition behavior because of their different M-O bond lengths originating from the Jahn-Teller distortions.
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Clinical value of polymerase chain reaction in the diagnosis of joint tuberculosis by detecting the DNA of Mycobacterium tuberculosis.
Orthop Surg
PUBLISHED: 10-20-2011
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To assess the clinical value of polymerase chain reaction (PCR) in the diagnosis and differential diagnosis of joint tuberculosis (TB).
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[Comparison study on polymerase chain reaction (PCR) and standard culture technique in detecting mycobacterium tuberculosis to diagnose of joint tuberculosis].
Zhongguo Gu Shang
PUBLISHED: 08-27-2009
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To study the role of PCR technique in detection of mycobacterium tuberculosis in the samples from joint tuberculosis, and to evaluate the clinical value of PCR in diagnosis of joint tuberculosis.
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Effects of exercise therapy on knee joint function and synovial fluid cytokine levels in patients with knee osteoarthritis.
Mol Med Rep
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The aims of this study were to observe the effect of exercise therapy on the function of the knee joint and the levels of cytokines and cytokine-related genes, specifically tumor necrosis factor-? (TNF-?), high sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinase-3 (MMP-3), in the synovial joints of patients with knee osteoarthritis (KOA) and to explore its mechanism of action. A total of 100 KOA patients were divided into a treatment group (n=50) and a control group (n=50) according to the order of admission. The patients in the treatment group were treated with diclofenac sodium combined with exercise therapy and the patients in the control group were treated with diclofenac sodium only. The function of the knee joint and the therapeutic efficacy was evaluated and the TNF-?, hs-CRP and MMP-3 levels in the synovial fluid were measured following 4 weeks of treatment. The results revealed that the knee joint index score and the TNF-?, hs-CRP and MMP-3 levels in the synovial fluid decreased significantly in the KOA patients of the two groups following treatment (P<0.05). Compared with the control group, the knee joint index score and the TNF-?, hs-CRP and MMP-3 levels in the synovial joints were lower and the therapeutic efficacy was increased in the patients of the treatment group (P<0.05). In brief, exercise therapy may decrease cytokine and cytokine-related gene levels in the synovial fluid and inhibit inflammatory factor-mediated cartilage degradation in KOA patients, thus, effectively improving the clinical symptoms of KOA.
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JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

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In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.