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Find video protocols related to scientific articles indexed in Pubmed.
Surgical endodontic reintervention using a modern technique: 2 case reports.
Gen Dent
PUBLISHED: 09-04-2014
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Management of post-treatment apical periodontitis after surgery--assuming the tooth is restorable, periodontally sound, and the patient desires to retain it--includes nonsurgical retreatment and surgical reintervention. This article presents 2 cases of surgical reintervention using a modern surgery technique that utilized an operating microscope, ultrasonic tips, and biocompatible materials. After the reinterventions were performed, adequate periradicular healing was observed in both cases. These cases reinforce the precept that combining knowledge about the biologic aspects of endodontics with surgical endodontic treatment using a modern technique is a predictable treatment option.
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Biocompatibility of a Self-adhesive Gutta-percha-based Material in Subcutaneous Tissue of Mice.
J Endod
PUBLISHED: 09-01-2014
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The purpose of this study was to evaluate the biocompatibility of a self-adhesive gutta-percha material and compare it with that of conventional gutta-percha.
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[Physical inactivity among non-institutionalized elderly individuals: a population-based study].
Cien Saude Colet
PUBLISHED: 08-15-2014
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The scope of this study is to assess the prevalence of physical inactivity among the elderly in Northeast Brazil and analyze the associated lifestyle and socio-demographic factors and health conditions. The work presented here is a descriptive and association-based study using secondary data derived from a population-based epidemiological study that included 316 elderly participants. The physical activity level of each participant was assessed using the International Physical Activity Questionnaire. The explanatory variables examined in this study were gender, age group, family set-up, ability to read and write, paid or voluntary employment, smoking, symptoms of depression, high blood pressure, fasting hyperglycemia and functional capacity. The prevalence of physical inactivity was 46.5. The results of the multivariate analysis indicated that physical inactivity was positively associated with the age group ? 80 years (PR = 2.37), with the lack of an occupation (PR = 4.86) and with dependence on instrumental activities of daily life (PR = 1.47) and basic activities of daily life (PR = 1.60). Physical inactivity was highly prevalent in the surveyed population, making it essential to discuss programs that encourage and enable increased physical activity to combat the risk factors of a sedentary lifestyle.
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Assessment of coronal leakage of a new temporary light-curing filling material in endodontically treated teeth.
Indian J Dent Res
PUBLISHED: 08-08-2014
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The aim of this study was to evaluate the sealing ability of a new temporary filling material X-Temp LC (DFL, São Paulo, SP, Brazil) compared with that obtained for Coltosol (Vigodent, Rio de Janeiro, RJ, Brazil) and Vitro Fill (DFL, Rio de Janeiro, RJ, Brazil), using a dye penetration test.
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S-Shaped Canals: A Series of Cases Performed by Four Specialists around the World.
Case Rep Dent
PUBLISHED: 07-16-2014
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Recognition of anatomical variations is a real challenge for clinicians undertaking therapy regardless of the teeth that are to be treated. The extent of the curvature is one of the most important variables that could lead to instrument fracture. In clinical conditions, two curves can be present in the same root canal trajectory. This type of geometry is denoted as the "S" shape, and it is a challenging condition. This report describes a different clinical and educational scenario where four specialists around the world present different approaches for the treatment of root canals with double curvatures or S-shaped canals. Endodontic therapy is a very nuanced and challenging science and art. The clinical and teaching experience of the authors show different approaches that can be successfully employed to treat challenging teeth having roots with multiple curves. The necessity of precise knowledge of the root canal morphology and its variation is also underlined.
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Lack of causal relationship between dentinal microcracks and root canal preparation with reciprocation systems.
J Endod
PUBLISHED: 04-21-2014
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This study aimed to evaluate the frequency of dentinal microcracks observed after root canal preparation with 2 reciprocating and a conventional full-sequence rotary system using micro-computed tomographic analysis.
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Maxillary premolar with 4 separate canals.
J Endod
PUBLISHED: 03-27-2014
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Recognition of anatomic variations is a challenge for clinicians regardless of which tooth is treated. Maxillary premolars usually have 2 root canals, but the presence of 3 distinct root canals has been reported in 1%-6% of cases.
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Assessment of apically extruded debris produced by the self-adjusting file system.
J Endod
PUBLISHED: 03-27-2014
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This study was designed to quantitatively evaluate the amount of apically extruded debris by the Self-Adjusting-File system (SAF; ReDent-Nova, Ra'anana, Israel). Hand and rotary instruments were used as references for comparison.
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Push-out bond strength of a self-adhesive resin cement used as endodontic sealer.
Restor Dent Endod
PUBLISHED: 03-17-2014
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The aim of the present study was to investigate the bond strength of RelyX Unicem (3M) to root canal dentin when used as an endodontic sealer.
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Evaluation of cytotoxicity, antimicrobial activity and physicochemical properties of a calcium aluminate-based endodontic material.
J Appl Oral Sci
PUBLISHED: 03-15-2014
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A calcium aluminate-based endodontic material, EndoBinder, has been developed in order to reduce MTA negative characteristics, preserving its biological properties and clinical applications.
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Constricted canals: a new strategy to overcome this challenge.
Case Rep Dent
PUBLISHED: 02-19-2014
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Negotiation of constricted canals can be a challenge during endodontic treatment. Over the years, several strategies have been presented in order to overcome the difficulties imposed by this anatomical feature. This paper presents three cases using a different protocol from that recommended by the manufacturer of the Protaper System in order to facilitate the negotiation of constricted canals. These cases suggest that the modified protocol shown is able to perform the shaping process with less resistance, reducing the risk of instrument separation and performing an effective process to reach the apical thirds in constricted canals.
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Evaluation of root canal configuration of maxillary molars in a Brazilian population using cone-beam computed tomographic imaging: an in vivo study.
J Endod
PUBLISHED: 01-28-2014
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The aim of this study was to analyze and characterize root canal morphology of maxillary molars of the Brazilian population using cone-beam computed tomographic (CBCT) imaging.
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Biodiversity effects of ecosystem engineers are stronger on more complex ecosystem processes.
Ecology
PUBLISHED: 11-28-2013
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The relative importance of species richness and identity for the diversity-function relationship remains controversial. We mechanistically explored the potential contribution of ecosystem processes complexity (EPC; i.e., the number of pathways and mechanisms through which an ecosystem process can be directly and/or indirectly affected by species and/or their interactions) to the resolution of this controversy. We hypothesized that the complementarity effects of biodiversity will be stronger and that the diversity-function relationship will be more dependent on species richness as the EPC increases. Using a benthic bioturbator community as a model system we tested these predictions across ecosystem processes that could be ordered according to their complexity (suspended material flux < PO4-P flux < NH4-N flux < bacterioplankton production). Consistent with our predictions, species richness explained an increasing proportion of data variation as EPC increased, whereas the contrary was observed for species composition. Nontransgressive overyielding was not affected by EPC, but the magnitude of transgressive overyielding increased significantly with EPC, indicating that complementarity may be stronger as EPC increases. Our results highlight the importance of considering the interactive role of the characteristics of ecosystem processes in our theoretical understanding of the diversity-function relationship and its underlying mechanisms.
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Validity of a Portable Glucose, Total Cholesterol, and Triglycerides Multi-Analyzer in Adults.
Biol Res Nurs
PUBLISHED: 07-19-2013
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This study investigated the accuracy and precision of the Accutrend Plus system to determine blood glucose, total cholesterol, and plasma triglycerides in adults and evaluated its efficiency in measuring these blood variables. The sample consisted of 53 subjects (? 18 years). For blood variable laboratory determination, venous blood samples were collected and processed in a Labmax 240 analyzer. To measure blood variables with the Accutrend Plus system, samples of capillary blood were collected. In the analysis, the following tests were included: Wilcoxon and Students t-tests for paired samples, Lins concordance coefficient, Bland-Altman method, receiver operating characteristic curve, McNemar test, and k statistics. The results show that the Accutrend Plus system provided significantly higher values (p ? .05) of glucose and triglycerides but not of total cholesterol (p > .05) as compared to the values determined in the laboratory. However, the system showed good reproducibility (Lins coefficient: glucose = .958, triglycerides = .992, total cholesterol = .940) and high concordance with the laboratory method (Lins coefficient: glucose = .952, triglycerides = .990, total cholesterol = .944) and high sensitivity (glucose = 80.0%, triglycerides = 90.5%, total cholesterol = 84.4%) and specificity (glucose = 100.0%, triglycerides = 96.9%, total cholesterol = 95.2%) in the discrimination of high values of the three blood variables analyzed. It could be concluded that despite the tendency to overestimate glucose and triglyceride levels, a portable multi-analyzer is a valid alternative for the monitoring of metabolic disorders and cardiovascular risk factors.
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Connective tissue reaction of rats to a new zinc-oxide-eugenol endodontic sealer.
Microsc. Res. Tech.
PUBLISHED: 07-04-2013
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The aim of this study was to evaluate the biocompatibility in rat subcutaneous connective tissue of a new zinc oxide endodontic sealer (Endomethasone N) compared to those provided by Endofill and Sealer 26. Polyethylene tubes containing the test materials were implanted into dorsal subcutaneous connective tissue of Wistar albino rats. After 7 and 42 days, the implants with the surrounding tissue were collected, fixed, and processed for histologic evaluation. Sections were evaluated for the presence of inflammatory cells (poly or monomorfonuclear), blood vessels, necrosis area, and thickness of fibrous capsule. Comparisons between groups and time-periods were performed with Kruskal-Wallis and Mann-Whitney U non-parametric tests for 5% significance level. No differences in the biocompatibility patterns among the materials for the 2 experimental periods were observed. Independently of the sealer, the tissue behavior showed a tendency to decrease the irritation effect over time. It can be concluded that all sealers are irritant, but its toxicity decreased with time. Endomethásone N showed biocompatible characteristics comparable with those provided by Endofill and Sealer 26.
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Anthropometric indicators of obesity as screening tools for high blood pressure in the elderly.
Int J Nurs Pract
PUBLISHED: 05-13-2013
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The study objectives were to investigate the indicators of obesity most associated with high blood pressure in community-dwelling elderly and identify among these which one best discriminates high blood pressure. This is an epidemiological, population, cross-sectional and home-based study of elderly people (? 60 years, n = 316) residing in northeastern Brazil. The results showed that the body mass index and the body adiposity index were the indicators more closely associated with high blood pressure in both sexes. Both in female and male genders, body mass index showed high values of specificity and low sensitivity values for discriminating high blood pressure, whereas the body adiposity index showed high sensitivity and moderate specificity values. In clinical practice and health surveillance, it is suggested that both indicators be used as screening tools for hypertension in the elderly.
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Lateral radiographic technique: an alternative approach for anterior teeth.
J Contemp Dent Pract
PUBLISHED: 04-13-2013
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To describe the lateral radiographic technique, its use and indication.
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L-arginine action in cutaneous flap evolution under nicotine exposure in rats.
Rev Col Bras Cir
PUBLISHED: 03-30-2013
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To evaluate whether treatment with L-arginine influences the healing of skin flaps in rats exposed to nicotine.
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Physical properties of MTA Fillapex sealer.
J Endod
PUBLISHED: 03-11-2013
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The aim of this study was to evaluate and compare several physicochemical properties including working and setting times, flow, solubility, and water absorption of a recent calcium silicate-based sealer (MTA Fillapex; Angelus, Londrina, Brazil) and an epoxy resin-based sealer (AH Plus; Dentsply, Konstanz, Germany).
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Evaluation of root canal configuration of mandibular molars in a Brazilian population by using cone-beam computed tomography: an in vivo study.
J Endod
PUBLISHED: 03-07-2013
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The aim of this study was to analyze and characterize root canal morphology of mandibular molars of the Brazilian population by using cone-beam computed tomography (CBCT).
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Random forests for feature selection in QSPR Models - an application for predicting standard enthalpy of formation of hydrocarbons.
J Cheminform
PUBLISHED: 02-04-2013
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One of the main topics in the development of quantitative structure-property relationship (QSPR) predictive models is the identification of the subset of variables that represent the structure of a molecule and which are predictors for a given property. There are several automated feature selection methods, ranging from backward, forward or stepwise procedures, to further elaborated methodologies such as evolutionary programming. The problem lies in selecting the minimum subset of descriptors that can predict a certain property with a good performance, computationally efficient and in a more robust way, since the presence of irrelevant or redundant features can cause poor generalization capacity. In this paper an alternative selection method, based on Random Forests to determine the variable importance is proposed in the context of QSPR regression problems, with an application to a manually curated dataset for predicting standard enthalpy of formation. The subsequent predictive models are trained with support vector machines introducing the variables sequentially from a ranked list based on the variable importance.
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Evaluation of gelatinases, tissue inhibitor of matrix metalloproteinase-2, and myeloperoxidase protein in healthy and inflamed human dental pulp tissue.
J Endod
PUBLISHED: 01-21-2013
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The aim of this study was to compare the gelatinolytic activity of matrix metalloproteinase (MMP)-2 and MMP-9 and the expression of tissue inhibitor of matrix metalloproteinase (TIMP)-2 and myeloperoxidase protein (MPO) in clinically healthy human pulp and inflamed pulp tissue specimens.
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Response of mice connective tissue to three different endodontic materials.
Microsc. Res. Tech.
PUBLISHED: 01-19-2013
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The aim of this study was to evaluate the biocompatibility of mineral trioxide aggregate (MTA) Bio and Portland cement (PC) and compare with those of ProRoot MTA. Polyethylene tubes were filled with materials and placed into dorsal subcutaneous connective tissue of Wistar albino rats. After 7, 30, and 60 days after the surgical procedure, the implants with the surrounding tissue were removed. Tissue samples were subjected to histological processing, and sections were stained with hematoxylin and eosin. Sections were evaluated for the intensity of inflammation, predominant cell type, presence of fibrous capsule and granulation tissue. Data were submitted to Kruskal-Wallis test at a significant level of P ? 0.05. No statistical differences were observed at any evaluated condition among tested materials (P > 0.05). Statistically significant differences were observed between mean inflammatory scores, cell types and granulation tissue of the same material in different experimental periods (P < 0.05). Can be concluded that biocompatibility of MTA bio and PC were comparable with that of ProRoot MTA.
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Long-term cytotoxic effects of contemporary root canal sealers.
J Appl Oral Sci
PUBLISHED: 01-07-2013
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The aim of the present study was to investigate the effects of root canal sealers on the cytotoxicity of 3T3 fibroblasts during a period of 5 weeks.
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Perioperative serum troponin I levels are associated with higher risk for atrial fibrillation in patients undergoing coronary artery bypass graft surgery.
Interact Cardiovasc Thorac Surg
PUBLISHED: 11-15-2011
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Atrial fibrillation (AF) remains a frequent complication after coronary artery bypass graft surgery (CABG). We evaluate the association of AF occurrence and serum cardiac troponin I (cTnI) levels in the early postoperative period after CABG. Between April 2009 and January 2010, 95 consecutive patients with sinus rhythm who underwent CABG were evaluated. The patients were divided into two groups according to their postoperative rhythms: sinus rhythm group (SR) and AF group (AF). Demographic, clinical variables, and troponin I were evaluated at the pre- and postoperative times. There were no clinical or demographic differences between the two groups. The postoperative troponin I in the SR group was lower than that in the AF group (0.66 ± 1.62 vs. 2.07 ± 5.01 ng/ml; P = 0.029). Using the receiver operating characteristic curves was found as the best cut-off value to predict AF occurrence at the value of 0.901 ng/ml. Using this value of cTnI, a sensitivity of 60% and a specificity of 87% for AF onset prediction were observed. The cTnI serum levels at the postoperative period after CABG were higher in patients who subsequently developed AF. The cut-off value of 0.901 ng/ml is useful for prediction and preventive therapeutic actions.
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Action of tacrolimus in arginine induced experimental acute pancreatitis.
Rev Col Bras Cir
PUBLISHED: 10-06-2011
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To determine whether tacrolimus administered to rats, in the presence of pancreatitis induced by L-Arginine, interferes with the serum levels of amylase and glucose and the histological pattern of the pancreatic parenchyma.
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Coronary artery bypass graft surgery after acute myocardial infarction caused by thrombosis of coronary aneurysm.
Rev Bras Cir Cardiovasc
PUBLISHED: 09-12-2011
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The morphology of coronary aneurysm sets a predisposing factor to thrombus formation. However, the blood stasis caused by the change in flow may not be enough to cause thromboembolic events.
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On the way to understand antioxidants: chromanol and dimethoxyphenols gas-phase acidities.
J Mass Spectrom
PUBLISHED: 06-15-2011
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Some antioxidant mechanisms displayed by several phenolic compounds relate with OH bond dissociation energy. One way for its determination, in the gas-phase, relies on acidity measurements. Gas-phase acidities were determined experimentally, applying the kinetic method, for chromanol and four dimethoxyphenols, and theoretically through quantum chemical DFT calculations for chromanol, six dimethoxyphenols and 3,4,5-trimethoxyphenol. The experimental acidity order, 2,3-dimethoxyphenol > 3,5-dimethoxyphenol > 2,6-dimethoxyphenol > 3,4-dimethoxyphenol ? phenol > chromanol shows good agreement with the theoretical acidity order, 2,5-dimethoxyphenol > 2,3-dimethoxyphenol > 3,4,5-trimethoxyphenol > 3,5-dimethoxyphenol ? 2,4-dimethoxyphenol > 2,6-dimethoxyphenol > 3,4-dimethoxyphenol > phenol > chromanol. These acidity trends were rationalized in terms of the substituent effects on the thermodynamic stabilities both of the parent phenols and the corresponding phenoxide ions. DFT calculations also evidenced the occurrence of intramolecular C-H···O hydrogen bonds whenever there are vicinal substituents (either OH, O(-) or OCH(3)) which induce further stabilization of the geometries.
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Sealing ability promoted by three different endodontic sealers.
Iran Endod J
PUBLISHED: 01-13-2011
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The aim of this study was to evaluate the apical and coronal seal of endodontic filling promoted by the combined use of Sealer 26/gutta-percha, Endofill/gutta-percha and Resilon/ Epiphany.
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Food web architecture and basal resources interact to determine biomass and stoichiometric cascades along a benthic food web.
PLoS ONE
PUBLISHED: 01-04-2011
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Understanding the effects of predators and resources on primary producers has been a major focus of interest in ecology. Within this context, the trophic cascade concept especially concerning the pelagic zone of lakes has been the focus of the majority of these studies. However, littoral food webs could be especially interesting because base trophic levels may be strongly regulated by consumers and prone to be light limited. In this study, the availability of nutrients and light and the presence of an omnivorous fish (Hyphessobrycon bifasciatus) were manipulated in enclosures placed in a humic coastal lagoon (Cabiúnas Lagoon, Macaé - RJ) to evaluate the individual and interactive effects of resource availability (nutrients and light) and food web configuration on the biomass and stoichiometry of periphyton and benthic grazers. Our findings suggest that light and nutrients interact to determine periphyton biomass and stoichiometry, which propagates to the consumer level. We observed a positive effect of the availability of nutrients on periphytic biomass and grazers biomass, as well as a reduction of periphytic C?N?P ratios and an increase of grazers N and P content. Low light availability constrained the propagation of nutrient effects on periphyton biomass and induced higher periphytic C?N?P ratios. The effects of fish presence strongly interacted with resource availability. In general, a positive effect of fish presence was observed for the total biomass of periphyton and grazers biomass, especially with high resource availability, but the opposite was found for periphytic autotrophic biomass. Fish also had a significant effect on periphyton stoichiometry, but no effect was observed on grazers stoichiometric ratios. In summary, we observed that the indirect effect of fish predation on periphyton biomass might be dependent on multiple resources and periphyton nutrient stoichiometric variation can affect consumers stoichiometry.
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Vaporisation of a dicationic ionic liquid revisited.
Chemphyschem
PUBLISHED: 11-09-2010
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The vaporization of a dicationic ionic liquid at moderate temperatures and under reduced pressures--recently studied by line-of-sight mass spectrometry--was further analyzed using an ion-cyclotron resonance mass spectroscopy technique that allows the monitoring of the different species present in the gas phase through the implementation of controlled ion-molecule reactions. The results support the view that the vapour phase of an aprotic dicationic ionic liquid is composed of neutral ion triplets (one dication attached to two anions). Molecular dynamics simulations were also performed in order to explain the magnitude of the vaporization enthalpies of dicationic ionic liquids vis-à-vis their monocationic counterparts.
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The nature of protic ionic liquids in the gas phase revisited: Fourier transform ion cyclotron resonance mass spectrometry study of 1,1,3,3-tetramethylguanidinium chloride.
J Phys Chem B
PUBLISHED: 06-24-2010
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The sublimation/vaporization of the protic ionic liquid 1,1,3,3-tetramethylguanidinium chloride, [Htmg]Cl, was studied by Fourier transform ion cyclotron resonance mass spectrometry in the temperature range 298-488 K and under a reduced pressure of 3.2 x 10(-6) to 1.5 x 10(-5) Pa. The results show that no charged species are present in the vapor over the condensed phase. Furthermore, ion-molecule reaction studies found no evidence of neutral ion pairs in the gas phase. This indicates that the sublimation/vaporization of [Htmg]Cl conforms to the general mechanism postulated for the distillation of protic ionic liquids, which involves a proton transfer leading to the formation of the neutral acid and base precursors, in this case hydrogen chloride and 1,1,3,3-tetramethylguanidine.
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[Experience with 100 pancreas transplants].
Rev Col Bras Cir
PUBLISHED: 06-16-2010
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Report our experience with 100 pancreas transplants performed in a period of seven years. METHODS. Between January 2001 and January 2008, 100 patients underwent pancreatic transplantation at our center, 88 simultaneous pancreas kidney transplantation (SPK) and 12 pancreas transplantation alone (PTA). All of these were primary transplants. Pancreas graft management of the exocrine drainage technique involved enteric drainage in 8 (all SPK) and bladder in 92 cases. The recipient systemic venous system was used for the pancreas graft venous effluent in all cases. Our last thirty patients submitted to SPK did not receive any induction therapy regardless of the PRA. SPK received basiliximab and PTA patients received thymoglubulin. Maintance imunossupression was with TAC, MMF and corticosteroids. Graft perfusion volume was limited to 800 ml of Celsior or UW solution. RESULTS. Overall results show that the number of functioning pancreatic grafts is 64 after 100 performed. Graft losses were: rejection (8 cases), venous thrombosis (9 cases) arterial thrombosis(1 case), or surgical complications such as anastomotic leak (3 cases), perigraft infection (10 cases), pancreatitis of the graft(5 cases). Rejection was observed less frequently in SPK recipients 5 cases (5/92 recipients) than PTA recipients (3/12). Death was observed in 24 cases. CONCLUSION. Our impression is that pancreas transplantation is highly effective therapy for diabetes mellitus and there is still a role in the diabetes treatment for allograft transplantation in a near future.
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[Glomerular filtration and associated factors in hypertensive individuals treated at primary care level].
Arq. Bras. Cardiol.
PUBLISHED: 04-02-2010
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In Brazil, arterial hypertension (AH) constitutes one of the main risk factors for chronic kidney disease (CKD). The monitoring of glomerular filtration (GF) is recommended for the assessment of kidney function in hypertensive individuals, as GF decrease precedes symptom onset.
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Successful endovascular management of a traumatic aortic rupture in a pediatric patient: case report and literature review.
Ulus Travma Acil Cerrahi Derg
PUBLISHED: 03-09-2010
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We report herein an 11-year-old pedestrian struck by a motorcycle, who suffered subdural hematoma and aortic rupture and developed traumatic pseudoaneurysm. He was treated conservatively for the first 24 hours and submitted to stent placement occluding the aneurysm neck. There were no recurrences in the post-procedure period and the child was discharged after 21 days without sequelae. This report also reviews trauma mechanisms and management of such threatening lesions in the pediatric population.
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Surgical treatment of chronic type A aortic dissection in patients undergoing coronary artery bypass grafting.
Rev Bras Cir Cardiovasc
PUBLISHED: 02-22-2010
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Surgical treatment of aortic dissection is a challenge for the cardiac surgeon, especially in patients undergoing cardiac operations. Our objective in this case report is to demonstrate how we treat the chronic type A aortic dissection in patients revascularized using percutaneous arterial and venous cannulae.
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Premolded bovine pericardial chords for replacement of ruptured or elongated chordae tendineae.
Heart Surg Forum
PUBLISHED: 02-13-2010
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The aim of this study was to assess by Doppler echocardiography (ECO) the functioning of the mitral valve apparatus in patients who have undergone implantation of standardized bovine pericardium chordae (SBPC) for replacement of ruptured or elongated chordae tendineae with significant thinning.
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Conscious sedation for upper digestive endoscopy performed by endoscopists.
Rev Bras Anestesiol
PUBLISHED: 02-10-2010
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Conscious sedation in the ambulatory setting albeit common is not risk-free. The present study aimed at evaluating the blood pressure, heart rate and peripheral oxygen saturation in patients submitted to conscious sedation for upper digestive endoscopy performed by endoscopists.
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Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.
Hum. Immunol.
PUBLISHED: 07-27-2009
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Leptospirosis is an emerging zoonotic disease caused by pathogenic species of the genus Leptospira. It has a broad range of clinical presentations in humans. Although progress has been made in the characterization of the host immune system factors that may affect disease progression and outcome, to date few reports have addressed the role of genetic polymorphisms in the susceptibility to leptospirosis. In this work a group of patients with a history of leptospiral infection and a control group were compared for polymorphisms in the human leukocyte antigen (HLA), in killer-cell immunoglobulin-like receptors (KIR), and in cytokine genes. Alleles in the HLA-A and -B loci were associated with susceptibility, as were the class I haplotype A*01-B*08-Cw*07 and the 8.1 ancestral haplotype (A*01-B*08-Cw*07-DRB1*03-DQB1*02). Single nucleotide polymorphisms in the interleukin (IL)-4 and IL-4Ralpha genes also had significantly higher frequencies in the patient group. No association was reported between KIR gene profile and leptospirosis. This work highlights the importance of using genetic polymorphisms to better understand the mechanisms involved in the immune response to leptospirosis.
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Prevalence and risk factors for acute renal failure in the postoperative of coronary artery bypass grafting.
Rev Bras Cir Cardiovasc
PUBLISHED: 06-16-2009
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To determine the prevalence, risk factors, and the clinical outcome of patients undergone coronary artery bypass grafting who progressed with Acute Renal Failure (ARF).
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Bridging the gap between ionic liquids and molten salts: group 1 metal salts of the bistriflamide anion in the gas phase.
J Phys Chem B
PUBLISHED: 03-13-2009
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Fourier transform ion cyclotron resonance mass spectrometry experiments showed that liquid Group 1 metal salts of the bistriflamide anion undergoing reduced-pressure distillation exhibit a remarkable behavior that is in transition between that of the vapor-liquid equilibrium characteristics of aprotic ionic liquids and that of the Group 1 metal halides: the unperturbed vapors resemble those of aprotic ionic liquids, in the sense that they are essentially composed of discrete ion pairs. However, the formation of large aggregates through a succession of ion-molecule reactions is closer to what might be expected for Group 1 metal halides. Similar experiments were also carried out with bis{(trifluoromethyl)sulfonyl}amine to investigate the effect of H(+), which despite being the smallest Group 1 cation, is generally regarded as a nonmetal species. In this case, instead of the complex ion-molecule reaction pattern found for the vapors of Group 1 metal salts, an equilibrium similar to those observed for aprotic ionic liquids was observed.
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Thoracic endovascular aortic repair - a Brazilian experience in 255 patients over a period of 112 months.
Interact Cardiovasc Thorac Surg
PUBLISHED: 02-05-2009
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The aim of this study is to analyze the immediate and late evolution for death and reintervention in a thoracic endovascular aortic repair (TEVAR) group, over a follow-up period of 112 months. Retrospective data of 255 patients, from 1998 to 2007, were obtained. The most prevalent diseases were thoracic aortic aneurysms (89), thoracic and abdominal aneurysms (85) and thoracic aortic dissections (61). The mean age was 63.2 years and 67.1% were male. Three hundred and three endoprostheses were used. Causes of morbidity, in the immediate postoperative period, were hyperthermia (45.9%), endoleaks (9.8% - being 7.1% type I), vascular complications (5.2%), renal insufficiency (3.1%) and neurological complications (3.1%). There were two (0.8%) hospital deaths and 17 (6.7%) late deaths. Time of follow-up was up to 112 months (mean of 60 months). The Kaplan-Meier curve analysis showed an increase of reintervention, compared with death, after a follow-up period of 42 months. Freedom from death at 36, 60 and 112 months was 96%, 89.1%, 85.1% and for reintervention, for the same periods was 93.6%, 82.7%, 57.2%, respectively. This study showed low incidence of prostheses related morbidity and immediate mortality. After a period of 42 months there was an increase on the percentual tax of reintervention.
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Hybrid treatment for correction of pseudoaneurysm after surgical treatment of aortic coarctation.
Rev Bras Cir Cardiovasc
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The need for a new surgical procedure for correction of postoperative pseudoaneurysm of aortic coarctation makes the procedure especially challenging for the surgeon.ta abstract.
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[Analysis of liver waiting list mortality in Paraná, Brazi: what shall we do to face organ shortage?].
Arq Bras Cir Dig
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Orthotopic liver transplantation is the best therapeutic modality for patients with end stage of liver disease. Minimization of death, while waiting for the procedure, involves accurate priorization according to clinical status and appropriate allocation of donor livers.
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Postoperative pain after foraminal enlargement in anterior teeth with necrosis and apical periodontitis: a prospective and randomized clinical trial.
J Endod
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The aim of this randomized, controlled, prospective clinical study was to determine if foraminal enlargement instrumentation during endodontic treatment is associated with more postoperative pain compared with standard nonenlargement instrumentation.
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Furcal-perforation repair with mineral trioxide aggregate: Two years follow-up.
Indian J Dent Res
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Furcal perforations are significant iatrogenic complications of endodontic treatment and could lead to endodontic failure. Mineral trioxide aggregate (MTA) has been regarded as an ideal material for perforation repair, retrograde filling, pulp capping, and apexification. This case report describes a furcal perforation in a maxillary first molar, which was repaired using MTA. The tooth was endodontically treated and coronally restored with resin composite. After 2 years, the absence of periradicular radiolucent lesions, pain, and swelling along with functional tooth stability indicated a successful outcome of sealing the perforation using MTA.
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Open apex type III dens invaginatus: a rare case report of an endodontic retreatment with an anatomical redesign.
Gen Dent
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Dens invaginatus is a critical condition for endodontic treatment. It frequently presents a complex internal anatomy and might be associated with incomplete root and apical development. This article presents one of the few reported cases of endodontic retreatment of Type III dens invaginatus. First, the internal anatomy was modified using burs under an operating microscope. Next, conventional chemical and mechanical preparation with hand files and 2.5% sodium hypochlorite was performed. Finally, an intracanal dressing with calcium hydroxide was used for nine months, at which point the anatomical features in the root canal system could be accessed. Adequate periradicular healing was observed and regression of the lesion was noted at the two-year follow-up. This case reinforces the idea that knowledge about the biologic aspects of endodontics, combined with adherence to technical standards, is helpful in resolving complex cases.
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Hypertriglyceridemic waist and cardiometabolic risk in hypertensive women.
Rev Assoc Med Bras
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To evaluate the association between hypertriglyceridemic waist (HW) and cardiometabolic risk factors in women with hypertension.
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Surgical Alternative for Treatment of Vertical Root fracture: A Case Report.
Iran Endod J
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Vertical root fracture (VRF) has been a great challenge in dentistry; most fractures often result in tooth extraction. Inflammation of tissues around the fractured root is the main reason for tooth extraction. Based on the strategic importance of some fractured teeth, treatment may be necessary and often complicated. However, performing a proper repair or even splinting the fractured segments may result in tooth preservation. Accordingly, in this case we report a new method for fractured tooth preservation. The surgical exposition of the fracture tooth was carried out through the radicular portion of the element via ultrasonic preparation, filling with composed resin and a synthetic hydroxyapatite graft. All these were performed around the tooth which received five sections of low-power laser. The patient was followed for two years with no signs or symptoms of inflammation and gingival recession. In conclusion, the used treatment protocol could be considered as a promising approach for VRF treatment, especially in cases where there is advanced or moderate bone loss in the surrounding sites of the fractured tooth.
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Community biomass and bottom up multivariate nutrient complementarity mediate the effects of bioturbator diversity on pelagic production.
PLoS ONE
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Tests of the biodiversity and ecosystem functioning (BEF) relationship have focused little attention on the importance of interactions between species diversity and other attributes of ecological communities such as community biomass. Moreover, BEF research has been mainly derived from studies measuring a single ecosystem process that often represents resource consumption within a given habitat. Focus on single processes has prevented us from exploring the characteristics of ecosystem processes that can be critical in helping us to identify how novel pathways throughout BEF mechanisms may operate. Here, we investigated whether and how the effects of biodiversity mediated by non-trophic interactions among benthic bioturbator species vary according to community biomass and ecosystem processes. We hypothesized that (1) bioturbator biomass and species richness interact to affect the rates of benthic nutrient regeneration [dissolved inorganic nitrogen (DIN) and total dissolved phosphorus (TDP)] and consequently bacterioplankton production (BP) and that (2) the complementarity effects of diversity will be stronger on BP than on nutrient regeneration because the former represents a more integrative process that can be mediated by multivariate nutrient complementarity. We show that the effects of bioturbator diversity on nutrient regeneration increased BP via multivariate nutrient complementarity. Consistent with our prediction, the complementarity effects were significantly stronger on BP than on DIN and TDP. The effects of the biomass-species richness interaction on complementarity varied among the individual processes, but the aggregated measures of complementarity over all ecosystem processes were significantly higher at the highest community biomass level. Our results suggest that the complementarity effects of biodiversity can be stronger on more integrative ecosystem processes, which integrate subsidiary "simpler" processes, via multivariate complementarity. In addition, reductions in community biomass may decrease the strength of interspecific interactions so that the enhanced effects of biodiversity on ecosystem processes can disappear well before species become extinct.
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[The first dual left lobe adult-to-adult liver transplantation in Brazil].
Rev Col Bras Cir
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Living donor liver transplantation expanded the therapeutic possibilities for liver failure patients. The necessary correct match between the liver mass donated and received sometimes limits its use. A case that was used two left liver grafts from adult living donors is reported.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.