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Find video protocols related to scientific articles indexed in Pubmed.
Preparing quality improvement, research, and evidence-based practice manuscripts.
Nurs Econ
PUBLISHED: 05-20-2014
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Understanding how to organize a manuscript reporting quality improvement (QI), research, and evidence-based practice (EBP) initiatives is important to provide essential information for readers to evaluate the findings for possible use in their own settings and replicate studies. Using guidelines for reporting QI, research studies, and EBP initiatives will help ensure authors submitting manuscripts to peer-reviewed publications report essential information and communicate it clearly to readers. This framework also guides the design and implementation of a project to ensure the information needed for a manuscript is collected and recorded for use in dissemination when the project is completed. Providing this specific information may also affect the likelihood of the manuscript being accepted for publication.
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Implementation of the Josie King Care Journal in a pediatric intensive care unit: a quality improvement project.
J Nurs Care Qual
PUBLISHED: 12-18-2013
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The Care Journal is a tool developed by the Josie King Foundation to promote interactive exchange among providers and patients/families. The Care Journal was implemented in a pediatric intensive care unit, and surveys were administered to assess perceptions about use. Parents who used the Care Journal and nursing staff found it to be a useful tool that improved communication, made parents feel more knowledgeable and empowered, and improved parents overall perception of the hospital stay.
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Modulation of annulus fibrosus cell alignment and function on oriented nanofibrous polyurethane scaffolds under tension.
Spine J
PUBLISHED: 06-27-2013
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Annulus fibrosus (AF), a component of the intervertebral disc (IVD), is always under tension in vivo, a condition that must be taken into consideration when tissue engineering an IVD. Loss of the tensile forces has been implicated in the pathogenesis of disc degeneration characterized by mechanical and structural breakdown of the AF.
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Patient-Held Maternal and/or Child Health Records: Meeting the Information Needs of Patients and Healthcare Providers in Developing Countries?
Online J Public Health Inform
PUBLISHED: 11-07-2011
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Though improvements in infant and maternal mortality rates have occurred over time, women and children still die every hour from preventable causes. Various regional, social and economic factors are involved in the ability of women and children to receive adequate care and prevention services. Patient-held maternal and/or child health records have been used for a number of years in many countries to help track health risks, vaccinations and other preventative health measures performed. Though these records are primarily designed to record patient histories and healthcare information and guide healthcare workers providing care, because the records are patient-held, they also allow families a greater ability to track their own health and prevention strategies. A LITERATURE SEARCH WAS PERFORMED TO ANSWER THESE QUESTIONS: (1) What are maternal information needs regarding pregnancy, post-natal and infant healthcare, especially in developing countries? (2) What is known about maternal information seeking behavior in developing countries? (3) What is the history and current state of maternal and/or child patient-held healthcare records, do they provide for the information needs of the healthcare provider and what are the effects and outcomes of patient-held records in general and for maternal and/or child health in particular? Specific information needs of pregnant women and mothers are rarely studied. The small numbers of maternal information behavior results available indicate that mothers, in general, prefer to receive health information directly from their healthcare provider as opposed to from other sources (written, etc.) Overall, in developing countries, patient-held maternal and/or child healthcare records have a mostly positive effect for both patient and care provider. Mothers and children with records tend to have better outcomes in healthcare and preventative measures. Further research into the information behaviors of pregnant women and mothers to determine the extent of reliance on interpersonal information seeking is recommended before expending significant resources on enhanced patient-held maternal and/or child healthcare records including storage on mobile devices. In particular, research is needed to explore the utility of providing targeted health messages to mothers regarding their own health and that of their children; this might best be accomplished through mobile technologies.
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Binding inhibitors of the bacterial sliding clamp by design.
J. Med. Chem.
PUBLISHED: 06-07-2011
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The bacterial replisome is a target for the development of new antibiotics to combat drug resistant strains. The ?(2) sliding clamp is an essential component of the replicative machinery, providing a platform for recruitment and function of other replisomal components and ensuring polymerase processivity during DNA replication and repair. A single binding region of the clamp is utilized by its binding partners, which all contain conserved binding motifs. The C-terminal Leu and Phe residues of these motifs are integral to the binding interaction. We acquired three-dimensional structural information on the binding site in ?(2) by a study of the binding of modified peptides. Development of a three-dimensional pharmacophore based on the C-terminal dipeptide of the motif enabled identification of compounds that on further development inhibited ?-?(2) interaction at low micromolar concentrations. We report the crystal structure of the complex containing one of these inhibitors, a biphenyl oxime, bound to ?(2), as a starting point for further inhibitor design.
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Experiences of pregnant women attending a lullaby programme in Limerick, Ireland: a qualitative study.
Midwifery
PUBLISHED: 04-17-2011
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to explore womens experience of singing lullabies in pregnancy and their understanding of possible benefits for themselves and their infants.
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The Limerick Lullaby project: an intervention to relieve prenatal stress.
Midwifery
PUBLISHED: 03-03-2011
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stress during pregnancy is common and has been linked to a range of poorer maternal and infant outcomes. Treatment options are few, however, due to difficulties of diagnosis and concerns about the impact of medication on the developing fetus. Singing is an activity with stress reducing and other benefits that may be worth exploring. The aim of this study was to explore the impact of singing lullabies during pregnancy.
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Synthesis, binding and bioactivity of gamma-methylene gamma-lactam ecdysone receptor ligands: advantages of QSAR models for flexible receptors.
Bioorg. Med. Chem.
PUBLISHED: 04-16-2010
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Nuclear hormone receptors, such as the ecdysone receptor, often display a large amount of induced fit to ligands. The size and shape of the binding pocket in the EcR subunit changes markedly on ligand binding, making modelling methods such as docking extremely challenging. It is, however, possible to generate excellent 3D QSAR models for a given type of ligand, suggesting that the receptor adopts a relatively restricted number of binding site configurations or attractors. We describe the synthesis, in vitro binding and selected in vivo toxicity data for gamma-methylene gamma-lactams, a new class of high-affinity ligands for ecdysone receptors from Bovicola ovis (Phthiraptera) and Lucilia cuprina (Diptera). The results of a 3D QSAR study of the binding of methylene lactams to recombinant ecdysone receptor protein suggest that this class of ligands is indeed recognised by a single conformation of the EcR binding pocket.
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Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides.
Bioorg. Med. Chem. Lett.
PUBLISHED: 10-09-2009
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A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.