JoVE Visualize What is visualize?
Stop Reading. Start Watching.
Advanced Search
Stop Reading. Start Watching.
Regular Search
Find video protocols related to scientific articles indexed in Pubmed.
Prevalence and risk factors for echinococcal infection in a rural area of northern Chile: a household-based cross-sectional study.
PLoS Negl Trop Dis
PUBLISHED: 08-28-2014
Show Abstract
Hide Abstract
Hydatidosis is a zoonotic disease of worldwide distribution caused by Echinococcus granulosus. Our study aimed to determine the prevalence of human and canine echinococcosis as well as the associated risk factors in a rural area of the Limarí province in northern Chile.
Related JoVE Video
[Latinamerican guidelines of RIICER for diagnosis of tick-borne rickettsioses].
Rev Chilena Infectol
PUBLISHED: 04-18-2014
Show Abstract
Hide Abstract
Tick-borne rickettsioses are worldwide infectious diseases that are considered emerging and re-emerging. Until recently the only tick-borne rickettsiosis present in Latin America was Rickettsia rickettsii infection, but to date, with the incorporation of new tools as PCR and sequencing and the quick cellular close tube cultures (Shell-vial), new species has been involved as human pathogens. In these guidelines, we offer an update of the microbiological assays for diagnosing rickettsioses. Besides we have included a section in which the most important hard ticks involved in human rickettsioses in Latinoamerica are detailed.
Related JoVE Video
[Nosocomial infections after cardiac surgery in infants and children with congenital heart disease].
Rev Chilena Infectol
PUBLISHED: 04-18-2014
Show Abstract
Hide Abstract
Nosocomial infections generate high morbidity and mortality in children undergoing cardiac surgery.
Related JoVE Video
[Concordance of nasal swabs and nasopharyngeal swabs in the detection of respiratory viruses by direct immunofluorescence].
Rev Chilena Infectol
PUBLISHED: 02-04-2014
Show Abstract
Hide Abstract
The most used test for the diagnosis of viral respiratory infection is the detection of viral antigens by direct immunofluorescence (DFA), in samples taken by nasopharyngeal swab (NPS) or aspirate (NPA). It would be desirable to have a less uncomfortable technique to obtain a sample from the patient, but of equal performance.
Related JoVE Video
Rickettsia felis in rhipicephalus sanguineus from two distant Chilean cities.
Vector Borne Zoonotic Dis.
PUBLISHED: 05-09-2013
Show Abstract
Hide Abstract
Rickettsia felis is an emerging agent considered a human threat; although its natural reservoir and agent of transmission is the cat flea, it has been also found in other vectors. R. felis has been identified in Chile in cat fleas and in one specimen of Rhipicephalus sanguineus collected in the Metropolitan Region. The objective of this study was to detect the presence of Rickettsia spp. in R. sanguineus from dogs of two different and distant geographical areas in Chile.
Related JoVE Video
[Pet ownership in inmunocompromised patients: update and veterinary and medical considerations].
Rev Chilena Infectol
PUBLISHED: 03-02-2013
Show Abstract
Hide Abstract
Pet ownership offers undisputed benefits to immunocompromised (IC) patients, however, it poses the risk for potentially serious zoonoses. Mechanisms of transmission and manifestation of major zoonotic infections in dogs and cats that may affect IC patients are described. We also provide updated international information and local data. Recommendations are given to choose and care for pets ensuring safe and responsible ownership. This will help to prevent, detect and treat infections timely.
Related JoVE Video
[Detection of Rickettsia andeanae in two regions of Chile].
Rev Chilena Infectol
PUBLISHED: 01-10-2013
Show Abstract
Hide Abstract
Candidatus Rickettsia andeanae is recently recognized specie, with no attributed pathogenic role so far. It has been reported in Amblyomma ticks from Peru, USA and Argentina, and recently in Chile, in one specimen of Amblyomma triste from a rural locality in Arica.
Related JoVE Video
[Accuracy and diagnostic utility of IgM in Bartonella henselae infections].
Rev Chilena Infectol
PUBLISHED: 01-05-2013
Show Abstract
Hide Abstract
Laboratory diagnosis of cat scratch disease (CSD) is based on the determination of specific antibodies anti-Bartonella henselae by different techniques. The CDC recommends IgG by immunofluorescent assay (IFA) as the gold standard.
Related JoVE Video
Endemic scrub typhus-like illness, Chile.
Emerging Infect. Dis.
PUBLISHED: 09-06-2011
Show Abstract
Hide Abstract
We report a case of scrub typhus in a 54-year-old man who was bitten by several terrestrial leeches during a trip to Chiloé Island in southern Chile in 2006. A molecular sample, identified as related to Orientia tsutsugamushi based on the sequence of the16S rRNA gene, was obtained from a biopsy specimen of the eschar on the patients leg. Serologic analysis showed immunoglobulin G conversion against O. tsutsugamushi whole cell antigen. This case and its associated molecular analyses suggest that an Orientia-like agent is present in the Western Hemisphere that can produce scrub typhus-like illness. The molecular analysis suggests that the infectious agent is closely related, although not identical, to members of the Orientia sp. from Asia.
Related JoVE Video
[Source of infection in young infants hospitalized with Bordetella pertussis].
Rev Med Chil
PUBLISHED: 08-25-2011
Show Abstract
Hide Abstract
Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. Aim: To determine the source of Pertussis infection in infants aged six months or less in Chile.
Related JoVE Video
[Sepsis due to Pseudomonas aeruginosa in a previously healthy infant].
Rev Chilena Infectol
PUBLISHED: 07-25-2011
Show Abstract
Hide Abstract
Pseudomonas aeruginosa, is an opportunistic organism widely distributed in both environmental and nosocomial settings. Invasive infections typically occur in immunocompromised patients, but this agent can also produce sepsis in the immunocompetent host. We report the case of an 8 months old infant, previous healthy, who presented septic shock by P. aeruginosa. Lesions of ecthyma gangrenosum in his limbs required surgical debridement. The patient presented transitory neutropenia and reduced C4 levels but subsequent study of immune defects was normal.
Related JoVE Video
[Pet ownership and health status of pets from immunocompromised children, with emphasis in zoonotic diseases].
Rev Chilena Infectol
PUBLISHED: 07-14-2011
Show Abstract
Hide Abstract
To characterize pet ownership and pet health status in families of immunocompromised (IS) children, with emphasis in zoonotic diseases.
Related JoVE Video
Immunogenicity and tolerability of a paediatric presentation of a virosomal hepatitis A vaccine in Chilean children aged 1-16 years.
Vaccine
PUBLISHED: 06-21-2011
Show Abstract
Hide Abstract
We assessed the immunogenicity of the paediatric dose of Epaxal(®) (0.25 mL) and the degrees of seroprotection achieved with the standard dose (0.5 mL) of Epaxal(®) or a dose of Havrix(®) Junior, in children in an open, randomised, controlled, multi-centre, parallel-group study conducted at 2 Chilean study centres. 360 healthy children and adolescents 12 months to <17 years of age not previously vaccinated against hepatitis A were enrolled. Subjects were randomised 2:2:1 to be vaccinated with either Epaxal(®) 0.25 mL [n=146], Epaxal(®) 0.5 mL [n=142] or Havrix(®) Junior [n=72] intramuscularly on Day 1 and after 6 months (26 weeks±14 days). Primary end point was the proportion of subjects seroprotected (anti-HAV antibody concentration ?10 mIU/mL) in the ATP population at Month 1. All vaccines elicited high seroprotection rates at Month 1: 95.7% with Epaxal(®) 0.25 mL, 99.3% with Epaxal(®) 0.5 mL and 94.0% with Havrix(®) Junior. After the booster vaccination, all subjects demonstrated 100% seroprotection with all vaccines. Antibody concentrations were similarly high in all age groups. The paediatric presentation achieved antibody concentrations similar to those achieved with the 0.5 mL dose across the entire age range, and there were no differences across the range of body weights from 9.0 kg to 82.7 kg. All study vaccines were well tolerated and there were no AEs leading to discontinuation. Thus, the paediatric 0.25 mL dose of Epaxal(®) fulfilled the primary objective of showing non-inferiority to the adult 0.5 mL dose and to Havrix(®) Junior, in terms of seroprotection rates achieved. The results show the paediatric dose of Epaxal(®) to be an attractive option when conducting childhood-vaccination programmes.
Related JoVE Video
IRF8 mutations and human dendritic-cell immunodeficiency.
N. Engl. J. Med.
PUBLISHED: 04-27-2011
Show Abstract
Hide Abstract
The genetic analysis of human primary immunodeficiencies has defined the contribution of specific cell populations and molecular pathways in the host defense against infection. Disseminated infection caused by bacille Calmette-Guérin (BCG) vaccines is an early manifestation of primary immunodeficiencies, such as severe combined immunodeficiency. In many affected persons, the cause of disseminated BCG disease is unexplained.
Related JoVE Video
Partial recessive IFN-?R1 deficiency: genetic, immunological and clinical features of 14 patients from 11 kindreds.
Hum. Mol. Genet.
PUBLISHED: 01-25-2011
Show Abstract
Hide Abstract
We report a series of 14 patients from 11 kindreds with recessive partial (RP)-interferon (IFN)-?R1 deficiency. The I87T mutation was found in nine homozygous patients from Chile, Portugal and Poland, and the V63G mutation was found in five homozygous patients from the Canary Islands. Founder effects accounted for the recurrence of both mutations. The most recent common ancestors of the patients with the I87T and V63G mutations probably lived 1600 (875-2950) and 500 (200-1275) years ago, respectively. The two alleles confer phenotypes that are similar but differ in terms of IFN-?R1 levels and residual response to IFN-?. The patients suffered from bacillus Calmette-Guérin-osis (n= 6), environmental mycobacteriosis (n= 6) or tuberculosis (n= 1). One patient did not suffer from mycobacterial infections but had disseminated salmonellosis, which was also present in two other patients. Age at onset of the first environmental mycobacterial disease differed widely between patients, with a mean value of 11.25 ± 9.13 years. Thirteen patients survived until the age of 14.82 ± 11.2 years, and one patient died at the age of 7 years, 9 days after the diagnosis of long-term Mycobacterium avium infection and the initiation of antimycobacterial treatment. Up to 10 patients are currently free of infection with no prophylaxis. The clinical heterogeneity of the 14 patients was not clearly related to either IFNGR1 genotype or the resulting cellular phenotype. RP-IFN-?R1 deficiency is, thus, more common than initially thought and should be considered in both children and adults with mild or severe mycobacterial diseases.
Related JoVE Video
A phase 2, randomized, double-blind safety and pharmacokinetic assessment of respiratory syncytial virus (RSV) prophylaxis with motavizumab and palivizumab administered in the same season.
BMC Pediatr
PUBLISHED: 06-03-2010
Show Abstract
Hide Abstract
Respiratory syncytial virus (RSV) is an important pathogen causing annual epidemics of bronchiolitis and pneumonia among infants worldwide. High-risk infants currently receive RSV prophylaxis with palivizumab, a humanized RSV monoclonal antibody (MAb). In preclinical in vitro and in vivo (cotton-rat model) studies, motavizumab, a new RSV MAb, was shown to have greater anti-RSV activity than palivizumab. Motavizumab is currently under review for licensing approval. Since both MAbs may be available concurrently, this study evaluated their safety and tolerability when administered sequentially during the same RSV season.
Related JoVE Video
[23-valent pneumococcal vaccine. Statement of the Consultive Committee of Immunizations on behalf of the Chilean Infectious Diseases Society: February 2010].
Rev Chilena Infectol
PUBLISHED: 05-13-2010
Show Abstract
Hide Abstract
The article summarizes the scientific evidence related with protection conferred by the 23 valent polysaccharide vaccine against invasive pneumococcal disease, non bacteraemic pneumococcal pneumonia, and probable pneumococcal pneumonia in the elderly. Eider patients with and without risk factors are considered. The impact of herd immunity conferred by vaccination of children with conjugated pneumococcal vaccine in reduction of pneumonia in adults is discussed. Based on this analysis, the Advisory Committee on Immunizations of the Chilean Infectious Disease Society makes recommendations on the most efficient vaccine strategy for reduction of pneumococcal pneumonia in the elderly.
Related JoVE Video
Primary and booster vaccination in Latin American children with a DTPw-HBV/Hib combination: a randomized controlled trial.
BMC Infect. Dis.
PUBLISHED: 02-25-2010
Show Abstract
Hide Abstract
Diphtheria-tetanus-whole-cell pertussis (DTPw)-based combination vaccines are an attractive option to rapidly achieve high coverage and protection against other important pathogens, such as hepatitis B virus (HBV) and Haemophilus influenzae type B (Hib). To ensure adequate antigen supply, GlaxoSmithKline Biologicals has introduced a new DTPw antigen source and developed a new DTPw-HBV/Hib combination vaccine containing a reduced amount of Hib polyribosylribitol phosphate (PRP). This study was undertaken to compare the immunogenicity and reactogenicity of this new DTPw-HBV/Hib vaccine with a licensed DTPw-HBV/Hib vaccine (Tritanrix™-HBV/Hib).
Related JoVE Video
Surveillance system for infectious diseases of pets, Santiago, Chile.
Emerging Infect. Dis.
PUBLISHED: 10-29-2009
Show Abstract
Hide Abstract
Pet diseases may pose risks to human health but are rarely included in surveillance systems. A pilot surveillance system of pet infectious diseases in Santiago, Chile, found that 4 canine and 3 feline diseases accounted for 90.1% and 98.4% of notifications, respectively. Data also suggested association between poverty and pet diseases.
Related JoVE Video
[Adverse reactions to diphtheria-pertussis-tetanus vaccine in the Chilean Immunization Program].
Rev Med Chil
PUBLISHED: 04-23-2009
Show Abstract
Hide Abstract
During 2005, the surveillance system of the Chilean Immunization Program detected an increased number of adverse reaction notifications associated to diphtheria, pertussis and tetanus whole-cell vaccine (DPT), coincidently with a change in the vaccine manufacturer.
Related JoVE Video
Safety, tolerability, pharmacokinetics, and immunogenicity of motavizumab, a humanized, enhanced-potency monoclonal antibody for the prevention of respiratory syncytial virus infection in at-risk children.
Pediatr. Infect. Dis. J.
PUBLISHED: 03-05-2009
Show Abstract
Hide Abstract
: Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in young children. Motavizumab is an investigational humanized monoclonal antibody for RSV prophylaxis.
Related JoVE Video
[Ramsay Hunt syndrome in children: four cases and review].
Rev Chilena Infectol
PUBLISHED: 01-29-2009
Show Abstract
Hide Abstract
Ramsay-Hunt Syndrome (RHS) is a rare affection characterized by peripheral facial paralysis (PFP), skin eruption in the auricular canal and cochleovestibular symptoms. It is produced by varicella-zoster virus (VZV) reactivation at the geniculate ganglia. We report four patients between 3 and 17 years-old with RHS. Earache was the first symptom in two cases and three had cochleovestibular compromise. The direct immunofluorescence from the vesicular lesion was positive for VZV in two of them. All patients received treatment with aeyelovir and in three cases, this was associated with steroids. Three children had complete resolution of the PFP. RHS is an infrequent disease in the pediatric population and it should be suspected in children with PFP, erythema, vesicles and/or auricular pain. Early treatment with aeyelovir therapy could improve the recovery rate of facial nerve palsy.
Related JoVE Video
[Human papillomavirus vaccine. Statement of the Consultive Committee of Immunizations on behalf of the Chilean Infectious Diseases Society. September 2008].
Rev Chilena Infectol
PUBLISHED: 01-29-2009
Show Abstract
Hide Abstract
The article briefly reviews the epidemiology of human papillomavirus (HPV) infection and associated diseases in the world and in Chile and the scientific information of the licensed HPV vaccines: Gardasil and Cervarix. Considering the available information, the Consultive Committee of Immunizations of the Chilean Society of Infectious Diseases, summarizes its conclusions and makes recommendations for vaccination against HPV in Chile.
Related JoVE Video
[Effectiveness of varicella vaccine as post exposure prophylaxis in Chilean children].
Rev Chilena Infectol
Show Abstract
Hide Abstract
Efficacy and effectiveness of varicella vaccine (VV) as post exposure prophylaxis (PEP) strategy have shown discordant results for disease risk reduction, and more consistent results in their ability to attenuate the disease.
Related JoVE Video
[Molecular identification of Ehrlichia canis in a dog from Arica, Chile].
Rev Chilena Infectol
Show Abstract
Hide Abstract
We report a molecular confirmed case of canine ehrlichiosis caused by Ehrlichia canis. A 10-year old female crossbred Siberian from the city of Arica, which was infested by ticks, presented hemorrhagic manifestations (hematomas and snout bleeding) and prostration. Blood cell count revealed thrombocytopenia (30,000 platelets/ mm³). Immunochromatographic rapid testing for E. canis IgG was positive. Amplification and sequencing of a fragment of the 16S rRNA gen from a blood sample showed 100% homology with E. canis from Perú. This is the first report of E. canis in Chile, an agent with known zoonotic potential.
Related JoVE Video
[Morphological and molecular identification of canine filariae in a semi-rural district of the Metropolitan Region in Chile].
Rev Chilena Infectol
Show Abstract
Hide Abstract
Introduction: To date, there has been no definitive confirmation of the presence of zoonotic dirofilariasis in dogs in Chile. Objectives: To study the presence of dirofilarias in blood samples from dogs collected in a semi-rural district near Santiago and to compare their frequency in dogs with and without dermatological manifestations. Methods: We examined 100 blood samples for dog filariae infections using microscopic methods (modified Knott technique). 50 dogs presented dermatological symptoms or signs compatible with filarial infections and 50 were asymptomatic. ITS-2 and 12s rDNA gene amplification by PCR and sequencing were performed in samples microscopically positive for microfilariae. Results. We observed microfilariae in 22 dogs (22%). Of these, 16/50 (32%) were symptomatic and 6/50 (12%) were asymptomatic (p = 0.02). Morphologically, the majority of micro-filariae were similar to Dirofilaria repens, although many had a bigger size than previously described. Nucleotide sequencing of the amplified genes showed no more than 95% homology with the D. repens sequences available for comparison. D. reconditum and D. dracunculoides infections were also identified. Conclusions: These features might indicate the presence of new species of Dirofilaria or a D. repens close related variant in Chile.
Related JoVE Video
A third Amblyomma species and the first tick-borne rickettsia in Chile.
J. Med. Entomol.
Show Abstract
Hide Abstract
During November 2010, three ticks were collected from three dogs living in the rural area of Arica, northern Chile. Morphological analyses of the ticks in the laboratory revealed that they were most similar to Amblyomma maculatum Koch and Amblyomma triste Koch. However, because of unique metatarsal spurs, neither of the Chilean specimens could be assigned with certainty to A. maculatum or A. triste, based on external morphology. The mitochondrial 16S rRNA gene partial sequences obtained from two Chilean specimens were 99.5% identical to A. triste from Uruguay, and 99.0% identical to A. maculatum from the United States. Through phylogenetic analysis inferred from partial 16S rRNA sequences, the Chilean specimens were classified as A. triste. Molecular analyses also showed that one of the three Chilean ticks was infected by Candidatus Rickettsia andeanae. These findings extend the geographical distribution of A. triste to Chile, where no tick-associated rickettsia had been reported previously.
Related JoVE Video

What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.