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Find video protocols related to scientific articles indexed in Pubmed.
Surgical interventions and medical treatments in treatment-naïve patients with acromegaly: systematic review and meta-analysis.
J. Clin. Endocrinol. Metab.
PUBLISHED: 10-30-2014
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Acromegaly is usually treated with surgery as a first-line treatment, although medical therapy has also been used as an alternative primary treatment.
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Clinical review: The benefits and harms of systemic dehydroepiandrosterone (DHEA) in postmenopausal women with normal adrenal function: a systematic review and meta-analysis.
J. Clin. Endocrinol. Metab.
PUBLISHED: 10-04-2014
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Exogenous dehydroepiandrosterone (DHEA) therapy has been proposed to replenish the depletion of endogenous DHEA and its sulfate form, which occurs with advancing age and is thought to be associated with loss of libido and menopausal symptoms.
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Creating a Patient-Centered Health Care Delivery System: A Systematic Review of Health Care Quality From the Patient Perspective.
Am J Med Qual
PUBLISHED: 08-02-2014
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Patient experience is one of key domains of value-based purchasing that can serve as a measure of quality and be used to improve the delivery of health services. The aims of this study are to explore patient perceptions of quality of health care and to understand how perceptions may differ by settings and condition. A systematic review of multiple databases was conducted for studies targeting patient perceptions of quality of care. Two reviewers screened and extracted data independently. Data synthesis was performed following a meta-narrative approach. A total of 36 studies were included that identified 10 quality dimensions perceived by patients: communication, access, shared decision making, provider knowledge and skills, physical environment, patient education, electronic medical record, pain control, discharge process, and preventive services. These dimensions can be used in planning and evaluating health care delivery. Future research should evaluate the effect of interventions targeting patient experience on patient outcomes.
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Comparative systematic review and meta-analysis of compression modalities for the promotion of venous ulcer healing and reducing ulcer recurrence.
J. Vasc. Surg.
PUBLISHED: 05-28-2014
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This was a systematic review of the literature to determine which compression method is superior in promoting ulcer healing and reducing recurrence in patients with lower extremity venous ulcer disease.
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Systematic review and meta-analysis of surgical interventions versus conservative therapy for venous ulcers.
J. Vasc. Surg.
PUBLISHED: 05-14-2014
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This goal of this study was to systematically review the literature to determine if surgical intervention (open or endovascular) is superior to compression alone with respect to ulcer healing, ulcer recurrence, and time to ulcer healing in patients with lower extremity venous ulcer disease.
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Extracorporeal photopheresis for chronic graft-versus-host disease: a systematic review and meta-analysis.
Blood Res
PUBLISHED: 04-07-2014
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The safety of extracorporeal photopheresis (ECP) in steroid-refractory chronic graft-versus-host disease (SR-cGVHD) has been explored in multiple studies but reported response rates (RR) vary significantly across studies.
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A systematic review of shared decision making interventions in chronic conditions: a review protocol.
Syst Rev
PUBLISHED: 04-01-2014
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Chronic conditions are a major source of morbidity, mortality and cost worldwide. Shared decision making is one way to improve care for patients with chronic conditions. Although it has been widely studied, the effect of shared decision making in the context of chronic conditions is unknown.
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Assessing the evidence: live attenuated influenza vaccine in children younger than 2 years. A systematic review.
Pediatr. Infect. Dis. J.
PUBLISHED: 03-18-2014
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Live attenuated influenza vaccine (LAIV) is effective in children but contraindicated in children <2 years of age.
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Testing for germline mutations in sporadic pheochromocytoma/paraganglioma: a systematic review.
Clin. Endocrinol. (Oxf)
PUBLISHED: 03-16-2014
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The presence of germline mutations in sporadic pheochromocytomas and paragangliomas (SPPs) may change the clinical management of both index patients and their family members. However, the frequency of germline mutations in SPPs is unknown.
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Health assessment of commercial drivers: a meta-narrative systematic review.
BMJ Open
PUBLISHED: 03-08-2014
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Motor vehicle accidents associated with commercial driving are an important cause of occupational death and impact public safety.
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Off-hour presentation and outcomes in patients with acute ischemic stroke: a systematic review and meta-analysis.
Eur. J. Intern. Med.
PUBLISHED: 03-07-2014
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Studies have suggested that patients with acute ischemic stroke who present to the hospital during off-hours (weekends and nights) may or may not have worse clinical outcomes compared to patients who present during regular hours.
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The association between sleep disturbances and suicidal behaviors in patients with psychiatric diagnoses: a systematic review and meta-analysis.
Syst Rev
PUBLISHED: 02-12-2014
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Identifying patients with increased risk of suicidal behaviors is a constant challenge and concern for clinicians caring for patients with psychiatric conditions. We conducted a systematic review to assess the association between suicidal behaviors and sleep disturbances in psychiatric patients.
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Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies.
Clin. Gastroenterol. Hepatol.
PUBLISHED: 01-28-2014
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Little is known about differences in rates of fibrosis progression between patients with nonalcoholic fatty liver (NAFL) vs nonalcoholic steatohepatitis (NASH). We conducted a systematic review and meta-analysis of all studies that assessed paired liver biopsy specimens to estimate the rates of fibrosis progression in patients with nonalcoholic fatty liver disease (NAFLD) including NAFL and NASH.
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Off-hour presentation and outcomes in patients with acute myocardial infarction: systematic review and meta-analysis.
BMJ
PUBLISHED: 01-24-2014
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To assess the association between off-hour (weekends and nights) presentation, door to balloon times, and mortality in patients with acute myocardial infarction.
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The accuracy of thyroid nodule ultrasound to predict thyroid cancer: systematic review and meta-analysis.
J. Clin. Endocrinol. Metab.
PUBLISHED: 11-25-2013
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Context:Significant uncertainty remains surrounding the diagnostic accuracy of sonographic features used to predict the malignant potential of thyroid nodulesObjective:To summarize the available literature related to the accuracy of thyroid nodule ultrasound (US) in the prediction of thyroid cancer.Methods:We searched multiple databases and reference lists for cohort studies that enrolled adults with thyroid nodules with reported diagnostic measures of sonography. A total of 14 relevant US features were analyzed.Results:We included 31 studies between 1985 and 2012 (number of nodules studied 18,288; average size 15 mm). The frequency of thyroid cancer was 20%. The most common type of cancer was papillary thyroid cancer (84%). The US nodule features with the highest diagnostic odds ratio (DOR) for malignancy was being "taller than wider" [11.14 (95% CI, 6.6-18.9)]. Conversely, the US nodule features with the highest DOR for benign nodules was spongiform appearance [12 (95% CI, 0.61-234.3)]. Heterogeneity across studies was substantial. Estimates of accuracy depended on the experience of the physician interpreting the US, the type of cancer and nodule (indeterminate), and type of reference standard. In a threshold model, spongiform appearance and cystic nodules were the only two features that, if present, could have avoided the use of fine-needle aspiration biopsy.Conclusions:Low to moderate quality evidence suggests that individual ultrasound features are not accurate predictors of thyroid cancer. Two features-cystic content and spongiform appearance-, however, might predict benign nodules but this has limited applicability to clinical practice due to their infrequent occurrence.
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Screening for gestational diabetes: a systematic review and meta-analysis.
J. Clin. Endocrinol. Metab.
PUBLISHED: 10-22-2013
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Gestational diabetes mellitus (GDM) is defined as any degree of hyperglycemia with first recognition during pregnancy. The optimal time to screen for GDM that would maximize the yield and benefits remains unclear.
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Provider-to-provider communication in dermatology and implications of missing clinical information in skin biopsy requisition forms: a systematic review.
Int. J. Dermatol.
PUBLISHED: 09-30-2013
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Various components of the skin biopsy requisition form (SBRF) may contribute to accurate dermatopathologic interpretation.
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Prevalence of thyroid cancer in multinodular goiter versus single nodule: a systematic review and meta-analysis.
Thyroid
PUBLISHED: 09-21-2013
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Whether the prevalence of thyroid cancer is different in thyroid glands with a single nodule (SN) versus multinodular goiter (MNG) remains uncertain. Therefore, a meta-analysis was performed to evaluate the extant literature on the comparative prevalence of thyroid cancer in SN compared with MNG.
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Comparative effectiveness of therapies for Graves hyperthyroidism: a systematic review and network meta-analysis.
J. Clin. Endocrinol. Metab.
PUBLISHED: 07-03-2013
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Several treatment options are available for Graves disease (GD), including antithyroid drugs (ATDs), radioactive iodine (RAI), and thyroidectomy.
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Using GRADE for evaluating the quality of evidence in hyperbaric oxygen therapy clarifies evidence limitations.
J Clin Epidemiol
PUBLISHED: 06-05-2013
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The current evidence rating for hyperbaric oxygen therapy indications uses the American Heart Association system, which mainly depends on the study design.
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Endovascular therapy for acute ischemic stroke: a systematic review and meta-analysis.
Mayo Clin. Proc.
PUBLISHED: 04-29-2013
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To consolidate the evidence from randomized trials for the use of endovascular therapy (ET) in patients with acute ischemic stroke.
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Care Coordination to Enhance Management of Long-Term Enteral Tube Feeding: A Systematic Review and Meta-Analysis.
JPEN J Parenter Enteral Nutr
PUBLISHED: 03-25-2013
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Background: A systematic review and meta-analysis was completed to summarize care delivery models that used care coordination and/or team approach methods in the management of patients requiring long-term enteral tube feeding. Our aim was to evaluate team composition, implementation strategies, and the effectiveness of these methods. Methods: We conducted a broad search of 7 databases from inception to May 2012, cross-referenced clinical reviews and medical guidelines, and consulted clinical experts. Independent reviewers screened eligible studies, extracted data, and assessed study quality. Results: Fifteen studies enrolling 2145 patients were included in this review. The studies described multidisciplinary teams composed of primary care physicians, specialists, nurses, dietitians, and language or speech specialists. Patients and their families/caregivers were also an important part of the care team. The interventions were multifaceted and employed multiple simultaneous strategies that particularly included patient and family education, staff education, and continuous auditing and feedback methods. Meta-analysis suggested no significant reductions in complications (incidence rate ratio [IRR], 0.53; 95% confidence interval [CI], 0.27-1.05), infections (IRR, 0.77; 95% CI, 0.48-1.24), and overall hospital admissions (IRR, 0.36; 95% CI, 0.13-1.00) most likely due to lack of statistical power. We found significant reduction of total hospital costs (estimates in US dollars: -623.08; 95% CI, -745.64 to -500.53; P < .01) after the interventions. Conclusion: Studies suggested a positive association of care coordination by a multidisciplinary team approach and improved patient outcomes for long-term enteral feeding patients. However, the available evidence does not allow estimating the effectiveness of a particular intervention or team composition.
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The association between anxiety disorders and suicidal behaviors: a systematic review and meta-analysis.
Depress Anxiety
PUBLISHED: 01-21-2013
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Although anxiety has been proposed to be a potentially modifiable risk factor for suicide, research examining the relationship between anxiety and suicidal behaviors has demonstrated mixed results. Therefore, we aimed at testing the hypothesis that anxiety disorders are associated with suicidal behaviors and evaluate the magnitude and quality of supporting evidence.
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Ageism vs. the technical imperative, applying the GRADE framework to the evidence on hemodialysis in very elderly patients.
Clin Interv Aging
PUBLISHED: 01-01-2013
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Treatment intensity for elderly patients with end-stage renal disease has escalated beyond population growth. Ageism seems to have given way to a powerful imperative to treat patients irrespective of age, prognosis, or functional status. Hemodialysis (HD) is a prime example of this trend. Recent articles have questioned this practice. This paper aims to identify existing pre-synthesized evidence on HD in the very elderly and frame it from the perspective of a clinician who needs to involve their patient in a treatment decision.
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Glycemic control in non-critically ill hospitalized patients: a systematic review and meta-analysis.
J. Clin. Endocrinol. Metab.
PUBLISHED: 11-16-2011
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The effect of intensive therapy to achieve tight glycemic control in patients hospitalized in non-critical care settings is unclear.
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The effect of lifestyle modification and cardiovascular risk factor reduction on erectile dysfunction: a systematic review and meta-analysis.
Arch. Intern. Med.
PUBLISHED: 09-12-2011
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Erectile dysfunction (ED) shares similar modifiable risks factors with coronary artery disease (CAD). Lifestyle modification that targets CAD risk factors may also lead to improvement in ED. We conducted a systematic review and meta-analysis of randomized controlled trials evaluating the effect of lifestyle interventions and pharmacotherapy for cardiovascular (CV) risk factors on the severity of ED.
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Mortality associated with atrial fibrillation in patients with myocardial infarction: a systematic review and meta-analysis.
Circulation
PUBLISHED: 04-04-2011
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Atrial fibrillation (AF) is a common finding in patients with myocardial infarction (MI). Atrial fibrillation is not generally perceived by clinicians as a critical event during the acute phase of MI; however, its prognostic influence in MI remains controversial. Furthermore, contradictory data exist concerning the risk of death according to AF timing. This article, a systematic review and first meta-analysis, aims to quantify the mortality risk associated with AF in MI patients and its timing.
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The effectiveness of self-directed learning in health professions education: a systematic review.
Med Educ
PUBLISHED: 10-16-2010
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Given the continuous advances in the biomedical sciences, health care professionals need to develop the skills necessary for life-long learning. Self-directed learning (SDL) is suggested as the methodology of choice in this context. The purpose of this systematic review is to determine the effectiveness of SDL in improving learning outcomes in health professionals.
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Sexual abuse and lifetime diagnosis of psychiatric disorders: systematic review and meta-analysis.
Mayo Clin. Proc.
PUBLISHED: 05-10-2010
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To systematically assess the evidence for an association between sexual abuse and a lifetime diagnosis of psychiatric disorders.
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Sexual abuse and lifetime diagnosis of somatic disorders: a systematic review and meta-analysis.
JAMA
PUBLISHED: 08-06-2009
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Many patients presenting for general medical care have a history of sexual abuse. The literature suggests an association between a history of sexual abuse and somatic sequelae.
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Meta-analysis of Glasgow coma scale and simplified motor score in predicting traumatic brain injury outcomes.
Brain Inj
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To perform a systematic review and meta-analysis to compare the simplified motor score (SMS) and Glasgow Coma Scale (GCS) in predicting outcomes in patients with traumatic brain injury (TBI). Data sources and study selection: Ovid EMBASE, Ovid Medline, Ovid PsycInfo, evidence-based medicine reviews and Scopus and related conference proceedings were searched through 28 February 2012 for studies comparing SMS and GCS in predicting the outcomes [emergency tracheal intubation (ETI), clinically significant brain injuries (CSBI), neurosurgical intervention (NSI) and mortality] in patients with TBI. A random-effects model was used for meta-analysis.
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What is preventable harm in healthcare? A systematic review of definitions.
BMC Health Serv Res
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Mitigating or reducing the risk of harm associated with the delivery of healthcare is a policy priority. While the risk of harm can be reduced in some instances (i.e. preventable), what constitutes preventable harm remains unclear. A standardized and clear definition of preventable harm is the first step towards safer and more efficient healthcare delivery system. We aimed to summarize the definitions of preventable harm and its conceptualization in healthcare.
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Care management for Type 2 diabetes in the United States: a systematic review and meta-analysis.
BMC Health Serv Res
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This systematic review and meta-analysis aims at assessing the composition and performance of care management models evaluated in the last decade and their impact on patient important outcomes.
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Endocrine clinical practice guidelines in North America. A systematic assessment of quality.
J Clin Epidemiol
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To assess the quality of endocrine guidelines developed in North America.
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What is Visualize?

JoVE Visualize is a tool created to match the last 5 years of PubMed publications to methods in JoVE's video library.

How does it work?

We use abstracts found on PubMed and match them to JoVE videos to create a list of 10 to 30 related methods videos.

Video X seems to be unrelated to Abstract Y...

In developing our video relationships, we compare around 5 million PubMed articles to our library of over 4,500 methods videos. In some cases the language used in the PubMed abstracts makes matching that content to a JoVE video difficult. In other cases, there happens not to be any content in our video library that is relevant to the topic of a given abstract. In these cases, our algorithms are trying their best to display videos with relevant content, which can sometimes result in matched videos with only a slight relation.