Ming-Daw Tsai Institute of Biological Chemistry Academia Sinica Biography Publications Institution JoVE Articles Ming-Daw Tsai has not added a biography. If you are Ming-Daw Tsai and would like to personalize this page please email our Author Liaison for assistance. Publications TIFA Protein Expression is Associated with Pulmonary Arterial Hypertension Scientific Reports. Jul, 2021 | Pubmed ID: 34238983 Synthesis of a Biotinylated Heptose 1,7-bisphosphate Analogue, a Probe to Study Immunity and Inflammation Organic & Biomolecular Chemistry. Jun, 2021 | Pubmed ID: 33988211 Identification of Fidelity-governing Factors in Human Recombinases DMC1 and RAD51 from Cryo-EM Structures Nature Communications. 01, 2021 | Pubmed ID: 33446654 Vibrio Cholerae Biofilm Scaffolding Protein RbmA Shows an Intrinsic, Phosphate-dependent Autoproteolysis Activity IUBMB Life. Feb, 2021 | Pubmed ID: 33372380 Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues Biochemistry. 06, 2020 | Pubmed ID: 32484330 Nonhydrolyzable Heptose Bis- and Monophosphate Analogues Modulate Pro-inflammatory TIFA-NF-κB Signaling Chembiochem : a European Journal of Chemical Biology. 10, 2020 | Pubmed ID: 32452604 9°N DNA Polymerase Exhibits 3'-esterase Activity That Can Be Harnessed for DNA Sequencing Communications Biology. 2019 | Pubmed ID: 31240262 Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn-Mediated Functions Journal of the American Chemical Society. 05, 2019 | Pubmed ID: 31067051 Binding and Enhanced Binding Between Key Immunity Proteins TRAF6 and TIFA Chembiochem : a European Journal of Chemical Biology. 01, 2019 | Pubmed ID: 30378729 Catalytic Mechanism of DNA Polymerases-Two Metal Ions or Three? Protein Science : a Publication of the Protein Society. 02, 2019 | Pubmed ID: 30368961 Twist and Turn: a Revised Structural View on the Unpaired Bubble of Class II CPD Photolyase in Complex with Damaged DNA IUCrJ. Sep, 2018 | Pubmed ID: 30224964 Structure of the Bifunctional Cryptochrome ACRY from Chlamydomonas Reinhardtii Nucleic Acids Research. 09, 2018 | Pubmed ID: 30032195 TagF-mediated Repression of Bacterial Type VI Secretion Systems Involves a Direct Interaction with the Cytoplasmic Protein Fha The Journal of Biological Chemistry. 06, 2018 | Pubmed ID: 29599293 STRENDA DB: Enabling the Validation and Sharing of Enzyme Kinetics Data The FEBS Journal. 06, 2018 | Pubmed ID: 29498804 Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation Biochemistry. 09, 2017 | Pubmed ID: 28858528 Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia Via the TRAF-Interacting Protein TIFA Cancer Research. 01, 2017 | Pubmed ID: 28069801 TIFA As a Crucial Mediator for NLRP3 Inflammasome Proceedings of the National Academy of Sciences of the United States of America. 12, 2016 | Pubmed ID: 27965388 The Nucleolar Protein NIFK Promotes Cancer Progression Via CK1α/β-catenin in Metastasis and Ki-67-dependent Cell Proliferation ELife. Mar, 2016 | Pubmed ID: 26984280 Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity Biochemistry. Dec, 2015 | Pubmed ID: 26529540 Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses Biochemistry. Oct, 2015 | Pubmed ID: 26389808 The RNA Recognition Motif of NIFK is Required for RRNA Maturation During Cell Cycle Progression RNA Biology. 2015 | Pubmed ID: 25826659 A Ribonuclease Coordinates SiRNA Amplification and MRNA Cleavage During RNAi Cell. Jan, 2015 | Pubmed ID: 25635455 Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo Molecular & Cellular Proteomics : MCP. Feb, 2014 | Pubmed ID: 33498138 PP2A and Aurora Differentially Modify Cdc13 to Promote Telomerase Release from Telomeres at G2/M Phase Nature Communications. Nov, 2014 | Pubmed ID: 25387524 Ultrafast Water Dynamics at the Interface of the Polymerase-DNA Binding Complex Biochemistry. Aug, 2014 | Pubmed ID: 25105470 Multiple Complexes of Long Aliphatic N-acyltransferases Lead to Synthesis of 2,6-diacylated/2-acyl-substituted Glycopeptide Antibiotics, Effectively Killing Vancomycin-resistant Enterococcus Journal of the American Chemical Society. Aug, 2014 | Pubmed ID: 25095906 Structure and Mechanism of a Nonhaem-iron SAM-dependent C-methyltransferase and Its Engineering to a Hydratase and an O-methyltransferase Acta Crystallographica. Section D, Biological Crystallography. Jun, 2014 | Pubmed ID: 24914966 How DNA Polymerases Catalyze DNA Replication, Repair, and Mutation Biochemistry. May, 2014 | Pubmed ID: 24716436 Fha Interaction with Phosphothreonine of TssL Activates Type VI Secretion in Agrobacterium Tumefaciens PLoS Pathogens. Mar, 2014 | Pubmed ID: 24626341 How a Low-fidelity DNA Polymerase Chooses Non-Watson-Crick from Watson-Crick Incorporation Journal of the American Chemical Society. Apr, 2014 | Pubmed ID: 24617852 Tight Regulation of a Timed Nuclear Import Wave of EKLF by PKCθ and FOE During Pro-E to Baso-E Transition Developmental Cell. Feb, 2014 | Pubmed ID: 24576425 Biosynthesis of Streptolidine Involved Two Unexpected Intermediates Produced by a Dihydroxylase and a Cyclase Through Unusual Mechanisms Angewandte Chemie (International Ed. in English). Feb, 2014 | Pubmed ID: 24505011 Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo Molecular & Cellular Proteomics : MCP. Feb, 2014 | Pubmed ID: 24302356 Interaction Between Salt-inducible Kinase 2 (SIK2) and P97/valosin-containing Protein (VCP) Regulates Endoplasmic Reticulum (ER)-associated Protein Degradation in Mammalian Cells The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24129571 Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase Molecular and Cellular Biology. Aug, 2013 | Pubmed ID: 23754745 Evidence That P12, a Specific Variant of P16(INK4A), Plays a Suppressive Role in Human Pancreatic Carcinogenesis Biochemical and Biophysical Research Communications. Jun, 2013 | Pubmed ID: 23727582 Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis Cancer Research. Aug, 2013 | Pubmed ID: 23722541 Phosphorylation of MRNA Decapping Protein Dcp1a by the ERK Signaling Pathway During Early Differentiation of 3T3-L1 Preadipocytes PloS One. 2013 | Pubmed ID: 23637887 Ubc9 Acetylation Modulates Distinct SUMO Target Modification and Hypoxia Response The EMBO Journal. Mar, 2013 | Pubmed ID: 23395904 Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23322770 Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease Molecular Cell. Dec, 2012 | Pubmed ID: 23123197 Amino Acid Substitutions of MagA in Klebsiella Pneumoniae Affect the Biosynthesis of the Capsular Polysaccharide PloS One. 2012 | Pubmed ID: 23118860 Intermolecular Binding Between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB Activation Molecular and Cellular Biology. Jul, 2012 | Pubmed ID: 22566686 SUMOylation of Blimp-1 is Critical for Plasma Cell Differentiation EMBO Reports. Jun, 2012 | Pubmed ID: 22555612 Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68 Biochemistry. Jan, 2012 | Pubmed ID: 22211259 Kinetic Mechanism of Active Site Assembly and Chemical Catalysis of DNA Polymerase β Biochemistry. Nov, 2011 | Pubmed ID: 22010960 E339...R416 Salt Bridge of Nucleoprotein As a Feasible Target for Influenza Virus Inhibitors Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21930946 Protein Kinase A-mediated Serine 35 Phosphorylation Dissociates Histone H1.4 from Mitotic Chromosome The Journal of Biological Chemistry. Oct, 2011 | Pubmed ID: 21852232 Functions of Some Capsular Polysaccharide Biosynthetic Genes in Klebsiella Pneumoniae NTUH K-2044 PloS One. 2011 | Pubmed ID: 21765903 Regulatory Mechanisms of Tumor Suppressor P16(INK4A) and Their Relevance to Cancer Biochemistry. Jun, 2011 | Pubmed ID: 21619050 Interception of Teicoplanin Oxidation Intermediates Yields New Antimicrobial Scaffolds Nature Chemical Biology. May, 2011 | Pubmed ID: 21478878 The Histone H3K36 Demethylase Rph1/KDM4 Regulates the Expression of the Photoreactivation Gene PHR1 Nucleic Acids Research. May, 2011 | Pubmed ID: 21296759 Regioselective Deacetylation Based on Teicoplanin-complexed Orf2* Crystal Structures Molecular BioSystems. Apr, 2011 | Pubmed ID: 21267472 High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase Activity Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20974907 Database Search Algorithm for Identification of Intact Cross-links in Proteins and Peptides Using Tandem Mass Spectrometry Journal of Proteome Research. Jul, 2010 | Pubmed ID: 20469931 Contributions of Conserved TPLH Tetrapeptides to the Conformational Stability of Ankyrin Repeat Proteins Journal of Molecular Biology. May, 2010 | Pubmed ID: 20398677 Unique Catalytic Mechanism of Phosphatidylinositol-specific Phospholipase C from Streptomyces Antibioticus Journal of the American Chemical Society. Feb, 2010 | Pubmed ID: 20052980 JNK-mediated Turnover and Stabilization of the Transcription Factor P45/NF-E2 During Differentiation of Murine Erythroleukemia Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 19966288 Unambiguous Determination of Isobaric Histone Modifications by Reversed-phase Retention Time and High-mass Accuracy Analytical Biochemistry. Jan, 2010 | Pubmed ID: 19699711 Trans-cyclization of Phosphatidylinositol Catalyzed by Phospholipase C from Streptomyces Antibioticus Journal of the American Chemical Society. Jun, 2009 | Pubmed ID: 19492832 AMP-activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633 Circulation Research. Feb, 2009 | Pubmed ID: 19131647 Humoral Immunity Against Capsule Polysaccharide Protects the Host from MagA+ Klebsiella Pneumoniae-induced Lethal Disease by Evading Toll-like Receptor 4 Signaling Infection and Immunity. Feb, 2009 | Pubmed ID: 19015249 Mismatched and Matched DNTP Incorporation by DNA Polymerase Beta Proceed Via Analogous Kinetic Pathways Biochemistry. Sep, 2008 | Pubmed ID: 18717589 Altered Order of Substrate Binding by DNA Polymerase X from African Swine Fever Virus Biochemistry. Jul, 2008 | Pubmed ID: 18598057 Diphosphothreonine-specific Interaction Between an SQ/TQ Cluster and an FHA Domain in the Rad53-Dun1 Kinase Cascade Molecular Cell. Jun, 2008 | Pubmed ID: 18570878 Mismatched DNTP Incorporation by DNA Polymerase Beta Does Not Proceed Via Globally Different Conformational Pathways Nucleic Acids Research. May, 2008 | Pubmed ID: 18385153 Solution Structures of 2 : 1 and 1 : 1 DNA Polymerase-DNA Complexes Probed by Ultracentrifugation and Small-angle X-ray Scattering Nucleic Acids Research. Feb, 2008 | Pubmed ID: 18084022 A Unique Flavin Mononucleotide-linked Primary Alcohol Oxidase for Glycopeptide A40926 Maturation Journal of the American Chemical Society. Nov, 2007 | Pubmed ID: 17935335 Dissection of Protein-protein Interaction and CDK4 Inhibition in the Oncogenic Versus Tumor Suppressing Functions of Gankyrin and P16 Journal of Molecular Biology. Nov, 2007 | Pubmed ID: 17881001 Identification of Histone Demethylases in Saccharomyces Cerevisiae The Journal of Biological Chemistry. May, 2007 | Pubmed ID: 17369256 ASFV DNA Polymerse X is Extremely Error-prone Under Diverse Assay Conditions and Within Multiple DNA Sequence Contexts Biochemistry. Dec, 2006 | Pubmed ID: 17144676 Glycopeptide Biosynthesis: Dbv21/Orf2 from Dbv/tcp Gene Clusters Are N-Ac-Glm Teicoplanin Pseudoaglycone Deacetylases and Orf15 from Cep Gene Cluster is a Glc-1-P Thymidyltransferase Journal of the American Chemical Society. Oct, 2006 | Pubmed ID: 17044690 Подготовка высокотемпературных сеток для отбора проб для крио-ЭМ Yuan-Chih Chang1,2, Chin-Yu Chen3,4, Ming-Daw Tsai1,5 1Institute of Biological Chemistry, Academia Sinica, 2Academia Sinica Cryo-EM Facility, Academia Sinica, 3Department of Life Sciences, National Central University, 4Hubei University, 5Institute of Biochemical Sciences, National Taiwan University JoVE 62772 Biochemistry
Подготовка высокотемпературных сеток для отбора проб для крио-ЭМ Yuan-Chih Chang1,2, Chin-Yu Chen3,4, Ming-Daw Tsai1,5 1Institute of Biological Chemistry, Academia Sinica, 2Academia Sinica Cryo-EM Facility, Academia Sinica, 3Department of Life Sciences, National Central University, 4Hubei University, 5Institute of Biochemical Sciences, National Taiwan University JoVE 62772 Biochemistry