Radislav Sedlacek

Publications

• Comprehensive ECG Reference Intervals in C57BL/6N Substrains Provide a Generalizable Guide for Cardiac Electrophysiology Studies in Mice
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Jun, 2023  |   Pubmed ID: 37294348
• Spatial Analysis of Nucleotide Metabolism: From CRISPR Knockout Cancer Cells to MALDI Imaging of Tumors
  Methods in Molecular Biology (Clifton, N.J.). 2023  |   Pubmed ID: 37258772
• Variation in Mouse Chemical Signals is Genetically Controlled and Environmentally Modulated
  Scientific Reports. May, 2023  |   Pubmed ID: 37237091
• A Structural Model of the IRhom-ADAM17 Sheddase Complex Reveals Functional Insights into Its Trafficking and Activity
  Cellular and Molecular Life Sciences : CMLS. Apr, 2023  |   Pubmed ID: 37119365
• Genome-wide Screening Reveals the Genetic Basis of Mammalian Embryonic Eye Development
  BMC Biology. Feb, 2023  |   Pubmed ID: 36737727
• Human Neutralizing Antibodies to Cold Linear Epitopes and Subdomain 1 of the SARS-CoV-2 Spike Glycoprotein
  Science Immunology. Mar, 2023  |   Pubmed ID: 36701425
• LACTB Induces Cancer Cell Death Through the Activation of the Intrinsic Caspase-independent Pathway in Breast Cancer
  Apoptosis : an International Journal on Programmed Cell Death. Feb, 2023  |   Pubmed ID: 36282364
• Molecular Interactions of Adaptor Protein PSTPIP2 Control Neutrophil-mediated Responses Leading to Autoinflammation
  Frontiers in Immunology. 2022  |   Pubmed ID: 36605205
• Human Neutralizing Antibodies to Cold Linear Epitopes and to Subdomain 1 of SARS-CoV-2
  BioRxiv : the Preprint Server for Biology. Nov, 2022  |   Pubmed ID: 36482967
• Analysis of Genome-wide Knockout Mouse Database Identifies Candidate Ciliopathy Genes
  Scientific Reports. Dec, 2022  |   Pubmed ID: 36456625
• Structural and Functional Basis of Mammalian MicroRNA Biogenesis by Dicer
  Molecular Cell. Nov, 2022  |   Pubmed ID: 36332606
• Self-reactivity of CD8 T-cell Clones Determines Their Differentiation Status Rather Than Their Responsiveness in Infections
  Frontiers in Immunology. 2022  |   Pubmed ID: 36275704
• Generation and Characterization of a Novel Angelman Syndrome Mouse Model with a Full Deletion of the Gene
  Cells. Sep, 2022  |   Pubmed ID: 36139390
• Full Assessment of Lung Mechanics Using Computer-Controlled, Forced Oscillation Technique
  Current Protocols. Jul, 2022  |   Pubmed ID: 35834677
• FBXO38 Ubiquitin Ligase Controls Sertoli Cell Maturation
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 35769260
• Batch Alignment Via Retention Orders for Preprocessing Large-scale Multi-batch LC-MS Experiments
  Bioinformatics (Oxford, England). Aug, 2022  |   Pubmed ID: 35748696
• Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA
  Non-coding RNA. May, 2022  |   Pubmed ID: 35645339
• Genome-wide Association Study Identifies Kallikrein 5 in Type 2 Inflammation-low Asthma
  The Journal of Allergy and Clinical Immunology. Apr, 2022  |   Pubmed ID: 35487308
• Semantic Clustering Analysis of E3-ubiquitin Ligases in Gastrointestinal Tract Defines Genes Ontology Clusters with Tissue Expression Patterns
  BMC Gastroenterology. Apr, 2022  |   Pubmed ID: 35413796
• Correction To: Plectin Ensures Intestinal Epithelial Integrity and Protects Colon Against Colitis
  Mucosal Immunology. Mar, 2022  |   Pubmed ID: 35301446
• Multi-Level Approach for Comprehensive Enamel Phenotyping
  Current Protocols. Jan, 2022  |   Pubmed ID: 35007410
• Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies
  Biological Psychiatry. Jul, 2022  |   Pubmed ID: 34865853
• Correction: Plectin Ensures Intestinal Epithelial Integrity and Protects Colon Against Colitis
  Mucosal Immunology. Feb, 2022  |   Pubmed ID: 34686840
• INFRAFRONTIER Quality Principles in Systemic Phenotyping
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Mar, 2022  |   Pubmed ID: 34328547
• The Receptor-type Protein Tyrosine Phosphatase CD45 Promotes Onset and Severity of IL-1β-mediated Autoinflammatory Osteomyelitis
  The Journal of Biological Chemistry. Oct, 2021  |   Pubmed ID: 34461100
• Heterozygous Mutation Affects Glucose Tolerance in Male Rats
  Genes. Jul, 2021  |   Pubmed ID: 34356103
• Publisher Correction: Bispecific IgG Neutralizes SARS-CoV-2 Variants and Prevents Escape in Mice
  Nature. Sep, 2021  |   Pubmed ID: 34345019
• Retraction Notice to "Fam208a Orchestrates Interaction Protein Network Essential for Early Embryonic Development and Cell Division" [Exp. Cell Res. 382 (1) (2019) 111437]
  Experimental Cell Research. Aug, 2021  |   Pubmed ID: 34272044
• Dual Role of Fam208a During Zygotic Cleavage and Early Embryonic Development
  Experimental Cell Research. Sep, 2021  |   Pubmed ID: 34216590
• LAMP3 Deficiency Affects Surfactant Homeostasis in Mice
  PLoS Genetics. Jun, 2021  |   Pubmed ID: 34161347
• Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate
  Frontiers in Cell and Developmental Biology. 2021  |   Pubmed ID: 34150743
• Deletion of TLR2 Erythro-myeloid Progenitors Leads to Embryonic Lethality in Mice
  European Journal of Immunology. Sep, 2021  |   Pubmed ID: 34107067
• ADAM10 and ADAM17 Regulate EGFR, C-Met and TNF RI Signalling in Liver Regeneration and Fibrosis
  Scientific Reports. 06, 2021  |   Pubmed ID: 34075077
• CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase During Spermatogenesis and T Cell Activation
  International Journal of Molecular Sciences. May, 2021  |   Pubmed ID: 34065512
• Regulation of Inflammatory Response by Transmembrane Adaptor Protein LST1
  Frontiers in Immunology. 2021  |   Pubmed ID: 33986741
• The IRhom Homology Domain is Indispensable for ADAM17-mediated TNFα and EGF Receptor Ligand Release
  Cellular and Molecular Life Sciences : CMLS. Jun, 2021  |   Pubmed ID: 33950315
• Expression of Human-specific ARHGAP11B in Mice Leads to Neocortex Expansion and Increased Memory Flexibility
  The EMBO Journal. Jul, 2021  |   Pubmed ID: 33938018
• Semi-Lethal Primary Ciliary Dyskinesia in Rats Lacking the Gene
  International Journal of Molecular Sciences. Apr, 2021  |   Pubmed ID: 33916973
• Cytoplasmic Polyadenylation by TENT5A is Required for Proper Bone Formation
  Cell Reports. Apr, 2021  |   Pubmed ID: 33882302
• A Resource of Targeted Mutant Mouse Lines for 5,061 Genes
  Nature Genetics. Apr, 2021  |   Pubmed ID: 33833456
• Response to Correspondence on "Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: a Multi-center Evaluation"
  Genome Biology. 04, 2021  |   Pubmed ID: 33827648
• Bispecific IgG Neutralizes SARS-CoV-2 Variants and Prevents Escape in Mice
  Nature. May, 2021  |   Pubmed ID: 33767445
• Plectin Ensures Intestinal Epithelial Integrity and Protects Colon Against Colitis
  Mucosal Immunology. 05, 2021  |   Pubmed ID: 33674761
• SGIP1 is Involved in Regulation of Emotionality, Mood, and Nociception and Modulates in Vivo Signalling of Cannabinoid CB Receptors
  British Journal of Pharmacology. Apr, 2021  |   Pubmed ID: 33491188
• Bardet-Biedl Syndrome Ciliopathy is Linked to Altered Hematopoiesis and Dysregulated Self-tolerance
  EMBO Reports. Feb, 2021  |   Pubmed ID: 33426789
• Efficient Allele Conversion in Mouse Zygotes and Primary Cells Based on Electroporation of Cre Protein
  Methods (San Diego, Calif.). Jul, 2021  |   Pubmed ID: 32717290
• Mouse Mutant Phenotyping at Scale Reveals Novel Genes Controlling Bone Mineral Density
  PLoS Genetics. Dec, 2020  |   Pubmed ID: 33370286
• Intronic Determinants Coordinate Charme LncRNA Nuclear Activity Through the Interaction with MATR3 and PTBP1
  Cell Reports. Dec, 2020  |   Pubmed ID: 33357424
• The IRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner
  International Journal of Molecular Sciences. Aug, 2020  |   Pubmed ID: 32825187
• Cytotoxicity of the Effector Protein BteA Was Attenuated In Bordetella Pertussis by Insertion of an Alanine Residue
  PLoS Pathogens. Aug, 2020  |   Pubmed ID: 32776984
• Toll-like Receptor Signaling in Thymic Epithelium Controls Monocyte-derived Dendritic Cell Recruitment and Treg Generation
  Nature Communications. May, 2020  |   Pubmed ID: 32398640
• Dysregulated NADPH Oxidase Promotes Bone Damage in Murine Model of Autoinflammatory Osteomyelitis
  Journal of Immunology (Baltimore, Md. : 1950). 03, 2020  |   Pubmed ID: 32024700
• The Deep Genome Project
  Genome Biology. Feb, 2020  |   Pubmed ID: 32008577
• Human and Mouse Essentiality Screens As a Resource for Disease Gene Discovery
  Nature Communications. Jan, 2020  |   Pubmed ID: 32005800
• High-throughput Discovery of Genetic Determinants of Circadian Misalignment
  PLoS Genetics. Jan, 2020  |   Pubmed ID: 31929527
• CRMP2 Mediates Sema3F-dependent Axon Pruning and Dendritic Spine Remodeling
  EMBO Reports. Mar, 2020  |   Pubmed ID: 31919978
• The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach
  Journal of Diabetes Research. 2019  |   Pubmed ID: 31886287
• Toll-like Receptor 2 Expression on C-kit Cells Tracks the Emergence of Embryonic Definitive Hematopoietic Progenitors
  Nature Communications. Nov, 2019  |   Pubmed ID: 31729371
• Truncated PPM1D Impairs Stem Cell Response to Genotoxic Stress and Promotes Growth of APC-deficient Tumors in the Mouse Colon
  Cell Death & Disease. Oct, 2019  |   Pubmed ID: 31659152
• Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: a Multi-center Evaluation
  Genome Biology. 08, 2019  |   Pubmed ID: 31446895
• Histone Methyltransferase PRDM9 is Not Essential for Meiosis in Male Mice
  Genome Research. Jul, 2019  |   Pubmed ID: 31186301
• Fam208a Orchestrates Interaction Protein Network Essential for Early Embryonic Development and Cell Division
  Experimental Cell Research. Sep, 2019  |   Pubmed ID: 31112734
• C-Myb Regulates Tumorigenic Potential of Embryonal Rhabdomyosarcoma Cells
  Scientific Reports. Apr, 2019  |   Pubmed ID: 31004084
• Aire-expressing ILC3-like Cells in the Lymph Node Display Potent APC Features
  The Journal of Experimental Medicine. May, 2019  |   Pubmed ID: 30918005
• Role of in Maternal MRNA Turnover
  Life Science Alliance. Aug, 2018  |   Pubmed ID: 30456367
• The Role of Immune Cell Subpopulations in the Growth and Rejection of TC-1/A9 Tumors in Novel Mouse Strains Differing in the H2-D Haplotype and NKC Domain
  Oncology Letters. Mar, 2018  |   Pubmed ID: 29467880
• Plectin Controls Biliary Tree Architecture and Stability in Cholestasis
  Journal of Hepatology. 05, 2018  |   Pubmed ID: 29273475
• Intrinsically Disordered Proteins Drive Enamel Formation Via an Evolutionarily Conserved Self-assembly Motif
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2017  |   Pubmed ID: 28196895
• KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
  PLoS Genetics. Jan, 2017  |   Pubmed ID: 28095415
• Knockout of Tmem70 Alters Biogenesis of ATP Synthase and Leads to Embryonal Lethality in Mice
  Human Molecular Genetics. Nov, 2016  |   Pubmed ID: 28173120
• Transgenic Reporter Mice with Promoter Region of Murine LRAT Specifically Marks Lens and Meiosis Spermatocytes
  Physiological Research. 2015  |   Pubmed ID: 25317684
• Efficient Gene Targeting of the Rosa26 Locus in Mouse Zygotes Using TALE Nucleases
  FEBS Letters. Nov, 2014  |   Pubmed ID: 25241166
• Liver Protective Effect of Ursodeoxycholic Acid Includes Regulation of ADAM17 Activity
  BMC Gastroenterology. Oct, 2013  |   Pubmed ID: 24172289