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JoVE Journal Cancer Research
Positronemissionstomografi Imaging af cellehandel
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Positronemissionstomografi Imaging af cellehandel: En metode til celleradiomærkning

Article DOI: 10.3791/64117-v • 10:07 min • October 27th, 2023
October 27th, 2023 •
1, 2, 1
1Division of Nuclear Medicine, Department of Radiology, Mayo Clinic, 2Department of Radiology, University of Colorado Anschutz Medical Campus

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Præsenteret her er en protokol til radiolabelceller med en positronemissionstomografi (PET) radioisotop, 89 Zr (t1/2 78,4 h), ved hjælp af en brugsklar radiomærkningssynthon, [89 Zr] Zr-p-isothiocyanatobenzyl-desferrioxamin ([89Zr] Zr-DBN). Radioaktive mærkningsceller med [89Zr] Zr-DBN tillader ikke-invasiv sporing og billeddannelse af administrerede radioaktivt mærkede celler i kroppen med PET i op til 7 dage efter administration.

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Kræftforskning nr. 200
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