Rocky S. Tuan Department of Orthopaedic Surgery University of Pittsburgh School of Medicine Biography Publications Institution JoVE Articles Rocky S. Tuan has not added a biography. If you are Rocky S. Tuan and would like to personalize this page please email our Author Liaison for assistance. Publications Synovial Joint-on-a-chip for Modeling Arthritis: Progress, Pitfalls, and Potential Trends in Biotechnology. Aug, 2022 | Pubmed ID: 35995600 Towards Establishing Human Body-on-a-chip Systems Stem Cell Research & Therapy. Aug, 2022 | Pubmed ID: 35987699 Aberrant Expression of and in Infrapatellar Fat Pad-Derived ASCs from Pre-Diabetic Donors Cells. Aug, 2022 | Pubmed ID: 35954211 Modeling Early Changes Associated with Cartilage Trauma Using Human-cell-laden Hydrogel Cartilage Models Stem Cell Research & Therapy. Aug, 2022 | Pubmed ID: 35927702 Tenogenic Induction of Human Adipose-derived Stem Cells by Soluble Tendon Extracellular Matrix: Composition and Transcriptomic Analyses Stem Cell Research & Therapy. Jul, 2022 | Pubmed ID: 35906661 Human Mesenchymal Stem Cell-Derived Miniature Joint System for Disease Modeling and Drug Testing Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jul, 2022 | Pubmed ID: 35436042 Dextran Sulfate-amplified Extracellular Matrix Deposition Promotes Osteogenic Differentiation of Mesenchymal Stem Cells Acta Biomaterialia. Mar, 2022 | Pubmed ID: 34875356 A High-Throughput Mechanical Activator for Cartilage Engineering Enables Rapid Screening of in Vitro Response of Tissue Models to Physiological and Supra-Physiological Loads Cells, Tissues, Organs. 2022 | Pubmed ID: 34261061 Macrophages Modulate the Function of MSC- and IPSC-Derived Fibroblasts in the Presence of Polyethylene Particles International Journal of Molecular Sciences. Nov, 2021 | Pubmed ID: 34884641 Graphene Oxide-functionalized Nanocomposites Promote Osteogenesis of Human Mesenchymal Stem Cells Via Enhancement of BMP-SMAD1/5 Signaling Pathway Biomaterials. Oct, 2021 | Pubmed ID: 34464823 Wdpcp Regulates Cellular Proliferation and Differentiation in the Developing Limb Via Hedgehog Signaling BMC Developmental Biology. Jul, 2021 | Pubmed ID: 34225660 Caveolin-1 Mediates Soft Scaffold-enhanced Adipogenesis of Human Mesenchymal Stem Cells Stem Cell Research & Therapy. Jun, 2021 | Pubmed ID: 34127047 The Effects of Macrophage Phenotype on Osteogenic Differentiation of MSCs in the Presence of Polyethylene Particles Biomedicines. May, 2021 | Pubmed ID: 34062822 An in Vitro Chondro-osteo-vascular Triphasic Model of the Osteochondral Complex Biomaterials. May, 2021 | Pubmed ID: 33798958 Development of a Large Animal Rabbit Model for Chronic Periprosthetic Joint Infection Bone & Joint Research. Mar, 2021 | Pubmed ID: 33641351 Load-induced Regulation of Tendon Homeostasis by SPARC, a Genetic Predisposition Factor for Tendon and Ligament Injuries Science Translational Medicine. Feb, 2021 | Pubmed ID: 33627488 Enhancing the Potential of Aged Human Articular Chondrocytes for High-quality Cartilage Regeneration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2021 | Pubmed ID: 33617078 Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling Handbook of Experimental Pharmacology. 2021 | Pubmed ID: 33471201 Current Models for Development of Disease-Modifying Osteoarthritis Drugs Tissue Engineering. Part C, Methods. Feb, 2021 | Pubmed ID: 33403944 Polyphenols Suppress Inducible Oxidative Stress in Human Osteoarthritic and Bovine Chondrocytes Osteoarthritis and Cartilage Open. Sep, 2020 | Pubmed ID: 36474689 Dead Muscle Tissue Promotes Dystrophic Calcification by Lowering Circulating TGF-β1 Level Bone & Joint Research. Nov, 2020 | Pubmed ID: 33135464 Mechanism of Traumatic Heterotopic Ossification: In Search of Injury-induced Osteogenic Factors Journal of Cellular and Molecular Medicine. Oct, 2020 | Pubmed ID: 32853465 Injectable BMP-2 Gene-activated Scaffold for the Repair of Cranial Bone Defect in Mice Stem Cells Translational Medicine. Dec, 2020 | Pubmed ID: 32785966 Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models Biology. Jul, 2020 | Pubmed ID: 32751156 Adipose Tissue-Derived Stem Cells Retain Their Adipocyte Differentiation Potential in Three-Dimensional Hydrogels and Bioreactors Biomolecules. Jul, 2020 | Pubmed ID: 32709032 Antimicrobial Activity of Mesenchymal Stem Cells Against Staphylococcus Aureus Stem Cell Research & Therapy. Jul, 2020 | Pubmed ID: 32680544 Gel and Cells: A Promising Reparative Strategy for Degenerated Intervertebral Discs EBioMedicine. May, 2020 | Pubmed ID: 32335373 Macrophage Effects on Mesenchymal Stem Cell Osteogenesis in a Three-Dimensional Bone Model Tissue Engineering. Part A. Oct, 2020 | Pubmed ID: 32312178 Tendon-derived Extracellular Matrix Induces Mesenchymal Stem Cell Tenogenesis Via an Integrin/transforming Growth Factor-β Crosstalk-mediated Mechanism FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2020 | Pubmed ID: 32301551 TGF-β1 Plays a Protective Role in Glucocorticoid-induced Dystrophic Calcification Bone. Jul, 2020 | Pubmed ID: 32259685 Acceleration of Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Sustained Growth Factor Release in 3D Graphene Oxide Incorporated Hydrogels Acta Biomaterialia. Mar, 2020 | Pubmed ID: 32035282 Incorporating Silica-coated Graphene in Bioceramic Nanocomposites to Simultaneously Enhance Mechanical and Biological Performance Journal of Biomedical Materials Research. Part A. Apr, 2020 | Pubmed ID: 31925910 Condensation-Driven Chondrogenesis of Human Mesenchymal Stem Cells Within Their Own Extracellular Matrix: Formation of Cartilage with Low Hypertrophy and Physiologically Relevant Mechanical Properties Advanced Biosystems. Dec, 2019 | Pubmed ID: 32648682 Osteochondral Tissue Chip Derived From IPSCs: Modeling OA Pathologies and Testing Drugs Frontiers in Bioengineering and Biotechnology. 2019 | Pubmed ID: 31921815 Modeling Appendicular Skeletal Cartilage Development with Modified High-density Micromass Cultures of Adult Human Bone Marrow-derived Mesenchymal Progenitor Cells Stem Cell Research & Therapy. Dec, 2019 | Pubmed ID: 31842986 A Cellularized Biphasic Implant Based on a Bioactive Silk Fibroin Promotes Integration and Tissue Organization During Osteochondral Defect Repair in a Porcine Model International Journal of Molecular Sciences. Oct, 2019 | Pubmed ID: 31627374 Muscle Injury Promotes Heterotopic Ossification by Stimulating Local Bone Morphogenetic Protein-7 Production Journal of Orthopaedic Translation. Jul, 2019 | Pubmed ID: 31508317 Efficient in Vivo Bone Formation by BMP-2 Engineered Human Mesenchymal Stem Cells Encapsulated in a Projection Stereolithographically Fabricated Hydrogel Scaffold Stem Cell Research & Therapy. Aug, 2019 | Pubmed ID: 31412905 Robust Bone Regeneration Through Endochondral Ossification of Human Mesenchymal Stem Cells Within Their Own Extracellular Matrix Biomaterials. Oct, 2019 | Pubmed ID: 31310952 Role of NGF-TrkA Signaling in Calcification of Articular Chondrocytes FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2019 | Pubmed ID: 31238006 A Bioactive Cartilage Graft of IGF1-Transduced Adipose Mesenchymal Stem Cells Embedded in an Alginate/Bovine Cartilage Matrix Tridimensional Scaffold Stem Cells International. 2019 | Pubmed ID: 31149016 Optimization of Photocrosslinked Gelatin/hyaluronic Acid Hybrid Scaffold for the Repair of Cartilage Defect Journal of Tissue Engineering and Regenerative Medicine. Aug, 2019 | Pubmed ID: 31066519 Conduits Harnessing Spatially Controlled Cell-secreted Neurotrophic Factors Improve Peripheral Nerve Regeneration Biomaterials. May, 2019 | Pubmed ID: 30857644 Engineering Hyaline Cartilage from Mesenchymal Stem Cells with Low Hypertrophy Potential Via Modulation of Culture Conditions and Wnt/β-catenin Pathway Biomaterials. Feb, 2019 | Pubmed ID: 30544046 Enhanced Repair of Meniscal Hoop Structure Injuries Using an Aligned Electrospun Nanofibrous Scaffold Combined with a Mesenchymal Stem Cell-derived Tissue Engineered Construct Biomaterials. Feb, 2019 | Pubmed ID: 30471629 Enhancing Chondrogenesis and Mechanical Strength Retention in Physiologically Relevant Hydrogels with Incorporation of Hyaluronic Acid and Direct Loading of TGF-β Acta Biomaterialia. Jan, 2019 | Pubmed ID: 30458242 Bone Marrow Mesenchymal Stem Cells: Aging and Tissue Engineering Applications to Enhance Bone Healing Biomaterials. May, 2019 | Pubmed ID: 29980291 Clinical Applications of Bone Tissue Engineering in Orthopedic Trauma Current Pathobiology Reports. Jun, 2018 | Pubmed ID: 36506709 Chondroinductive Factor-free Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Graphene Oxide-incorporated Hydrogels Journal of Materials Chemistry. B. Feb, 2018 | Pubmed ID: 32254371 Differences in Neural Stem Cell Identity and Differentiation Capacity Drive Divergent Regenerative Outcomes in Lizards and Salamanders Proceedings of the National Academy of Sciences of the United States of America. Aug, 2018 | Pubmed ID: 30104374 Effect of Platelet-Rich Plasma on Chondrogenic Differentiation of Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells Tissue Engineering. Part A. Oct, 2018 | Pubmed ID: 30036140 TISSUE REPAIR AND EPIMORPHIC REGENERATION: AN OVERVIEW Current Pathobiology Reports. Mar, 2018 | Pubmed ID: 29967714 Engineering In-vitro Stem Cell-based Vascularized Bone Models for Drug Screening and Predictive Toxicology Stem Cell Research & Therapy. Apr, 2018 | Pubmed ID: 29678192 Influence of Cholesterol/caveolin-1/caveolae Homeostasis on Membrane Properties and Substrate Adhesion Characteristics of Adult Human Mesenchymal Stem Cells Stem Cell Research & Therapy. Apr, 2018 | Pubmed ID: 29615119 3D Uniaxial Mechanical Stimulation Induces Tenogenic Differentiation of Tendon-derived Stem Cells Through a PI3K/AKT Signaling Pathway FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 09, 2018 | Pubmed ID: 29596022 Mesenchymal Stem Cell-derived Extracellular Matrix Enhances Chondrogenic Phenotype of and Cartilage Formation by Encapsulated Chondrocytes in Vitro and in Vivo Acta Biomaterialia. Mar, 2018 | Pubmed ID: 29317369 Neurotrophically Induced Mesenchymal Progenitor Cells Derived from Induced Pluripotent Stem Cells Enhance Neuritogenesis Via Neurotrophin and Cytokine Production Stem Cells Translational Medicine. Jan, 2018 | Pubmed ID: 29215199 Efficacy of Thermoresponsive, Photocrosslinkable Hydrogels Derived from Decellularized Tendon and Cartilage Extracellular Matrix for Cartilage Tissue Engineering Journal of Tissue Engineering and Regenerative Medicine. Jan, 2018 | Pubmed ID: 28486778 Cartilage and Muscle Cell Fate and Origins During Lizard Tail Regeneration Frontiers in Bioengineering and Biotechnology. 2017 | Pubmed ID: 29164111 Neurotrophic Support by Traumatized Muscle-derived Multipotent Progenitor Cells: Role of Endothelial Cells and Vascular Endothelial Growth Factor-A Stem Cell Research & Therapy. Oct, 2017 | Pubmed ID: 29029631 One-Step Fabrication of Bone Morphogenetic Protein-2 Gene-Activated Porous Poly-L-Lactide Scaffold for Bone Induction Molecular Therapy. Methods & Clinical Development. Dec, 2017 | Pubmed ID: 29018836 Chondrogenesis of Human Bone Marrow Mesenchymal Stem Cells in 3-dimensional, Photocrosslinked Hydrogel Constructs: Effect of Cell Seeding Density and Material Stiffness Acta Biomaterialia. Aug, 2017 | Pubmed ID: 28611002 Tissue-specific Bioactivity of Soluble Tendon-derived and Cartilage-derived Extracellular Matrices on Adult Mesenchymal Stem Cells Stem Cell Research & Therapy. Jun, 2017 | Pubmed ID: 28583182 Birth Defects: Etiology, Screening, and Detection Birth Defects Research. Jun, 2017 | Pubmed ID: 28568741 A Unified Birth Defects Research Birth Defects Research. Jan, 2017 | Pubmed ID: 27905204 Region-Specific Effect of the Decellularized Meniscus Extracellular Matrix on Mesenchymal Stem Cell-Based Meniscus Tissue Engineering The American Journal of Sports Medicine. Mar, 2017 | Pubmed ID: 27895039 Anatomical Region-dependent Enhancement of 3-dimensional Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Soluble Meniscus Extracellular Matrix Acta Biomaterialia. Feb, 2017 | Pubmed ID: 27876676 Tendon-Derived Extracellular Matrix Enhances Transforming Growth Factor-β3-Induced Tenogenic Differentiation of Human Adipose-Derived Stem Cells Tissue Engineering. Part A. Feb, 2017 | Pubmed ID: 27809678 Rapidly Dissociated Autologous Meniscus Tissue Enhances Meniscus Healing: An in Vitro Study Connective Tissue Research. 2017 | Pubmed ID: 27726454 Lizard Tail Regeneration As an Instructive Model of Enhanced Healing Capabilities in an Adult Amniote Connective Tissue Research. Mar, 2017 | Pubmed ID: 27459585 Prenatal Exposure to Environmental Factors and Congenital Limb Defects Birth Defects Research. Part C, Embryo Today : Reviews. Sep, 2016 | Pubmed ID: 27768243 Augmented Repair of Radial Meniscus Tear with Biomimetic Electrospun Scaffold: an in Vitro Mechanical Analysis Journal of Experimental Orthopaedics. Dec, 2016 | Pubmed ID: 27624439 Secreted Trophic Factors of Mesenchymal Stem Cells Support Neurovascular and Musculoskeletal Therapies Stem Cell Research & Therapy. Sep, 2016 | Pubmed ID: 27612948 Lizard Tail Skeletal Regeneration Combines Aspects of Fracture Healing and Blastema-based Regeneration Development (Cambridge, England). Aug, 2016 | Pubmed ID: 27387871 Prenatal Substance Use and Developmental Disorders: Overview and Highlights Birth Defects Research. Part C, Embryo Today : Reviews. Jun, 2016 | Pubmed ID: 27345012 Catabolic Effects of Endothelial Cell-derived Microparticles on Disc Cells: Implications in Intervertebral Disc Neovascularization and Degeneration Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Aug, 2016 | Pubmed ID: 27246627 Human Cartilage-Derived Progenitor Cells From Committed Chondrocytes for Efficient Cartilage Repair and Regeneration Stem Cells Translational Medicine. Jun, 2016 | Pubmed ID: 27130221 From Embryonic Development to Human Diseases: The Functional Role of Caveolae/caveolin Birth Defects Research. Part C, Embryo Today : Reviews. Mar, 2016 | Pubmed ID: 26991990 Multilayered Polycaprolactone/gelatin Fiber-hydrogel Composite for Tendon Tissue Engineering Acta Biomaterialia. Apr, 2016 | Pubmed ID: 26945631 Antibiotic-tolerant Staphylococcus Aureus Biofilm Persists on Arthroplasty Materials Clinical Orthopaedics and Related Research. Jul, 2016 | Pubmed ID: 26831479 Effect of Adipose-derived Stromal Cells and BMP12 on Intrasynovial Tendon Repair: A Biomechanical, Biochemical, and Proteomics Study Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Apr, 2016 | Pubmed ID: 26445383 Stem Cells in Skeletal Tissue Engineering: Technologies and Models Current Stem Cell Research & Therapy. 2016 | Pubmed ID: 26423296 Musculoskeletal Regeneration Research Network: A Global Initiative Journal of Orthopaedic Translation. Oct, 2015 | Pubmed ID: 30035054 Nascent Osteoblast Matrix Inhibits Osteogenesis of Human Mesenchymal Stem Cells in Vitro Stem Cell Research & Therapy. Dec, 2015 | Pubmed ID: 26696301 Expression of Concern: Human Amniotic Epithelial Cells Can Differentiate into Granulosa Cells and Restore Folliculogenesis in a Mouse Model of Chemotherapy-induced Premature Ovarian Failure Stem Cell Research & Therapy. Dec, 2015 | Pubmed ID: 26644000 Promotion of Human Mesenchymal Stem Cell Osteogenesis by PI3-kinase/Akt Signaling, and the Influence of Caveolin-1/cholesterol Homeostasis Stem Cell Research & Therapy. Dec, 2015 | Pubmed ID: 26626726 Cartilage Stem/progenitor Cells Are Activated in Osteoarthritis Via Interleukin-1β/nerve Growth Factor Signaling Arthritis Research & Therapy. Nov, 2015 | Pubmed ID: 26577823 Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering Frontiers in Bioengineering and Biotechnology. 2015 | Pubmed ID: 26347860 In Vitro Repair of Meniscal Radial Tear Using Aligned Electrospun Nanofibrous Scaffold Tissue Engineering. Part A. Jul, 2015 | Pubmed ID: 25813386 Molecular Diagnostics The Journal of the American Academy of Orthopaedic Surgeons. Apr, 2015 | Pubmed ID: 25808967 Platelet-Rich Plasma Inhibits Mechanically Induced Injury in Chondrocytes Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. Jun, 2015 | Pubmed ID: 25769480 Fiber Diameter and Seeding Density Influence Chondrogenic Differentiation of Mesenchymal Stem Cells Seeded on Electrospun Poly(ε-caprolactone) Scaffolds Biomedical Materials (Bristol, England). Jan, 2015 | Pubmed ID: 25634427 Lizard Tail Regeneration: Regulation of Two Distinct Cartilage Regions by Indian Hedgehog Developmental Biology. Mar, 2015 | Pubmed ID: 25596336 Origin and Function of Cartilage Stem/progenitor Cells in Osteoarthritis Nature Reviews. Rheumatology. Apr, 2015 | Pubmed ID: 25536487 Characterization of Bone Marrow-derived Mesenchymal Stem Cells in Aging Bone. Jan, 2015 | Pubmed ID: 25445445 Polymerase Chain Reaction Molecular Diagnostic Technology for Monitoring Chronic Osteomyelitis Journal of Experimental Orthopaedics. Dec, 2014 | Pubmed ID: 26914754 Endothelial and Cancer Cells Interact with Mesenchymal Stem Cells Via Both Microparticles and Secreted Factors Journal of Cellular and Molecular Medicine. Dec, 2014 | Pubmed ID: 25250510 Biology of Platelet-rich Plasma and Its Clinical Application in Cartilage Repair Arthritis Research & Therapy. Feb, 2014 | Pubmed ID: 25164150 Three-dimensional Osteogenic and Chondrogenic Systems to Model Osteochondral Physiology and Degenerative Joint Diseases Experimental Biology and Medicine (Maywood, N.J.). Sep, 2014 | Pubmed ID: 24994814 Functional Cartilage Repair Capacity of De-differentiated, Chondrocyte- and Mesenchymal Stem Cell-laden Hydrogels In vitro Osteoarthritis and Cartilage. Aug, 2014 | Pubmed ID: 24887551 Stem Cell-based Microphysiological Osteochondral System to Model Tissue Response to Interleukin-1β Molecular Pharmaceutics. Jul, 2014 | Pubmed ID: 24830762 Functional Comparison of Human-induced Pluripotent Stem Cell-derived Mesenchymal Cells and Bone Marrow-derived Mesenchymal Stromal Cells from the Same Donor Stem Cells and Development. Jul, 2014 | Pubmed ID: 24625206 Cartilage Tissue Engineering Application of Injectable Gelatin Hydrogel with in Situ Visible-light-activated Gelation Capability in Both Air and Aqueous Solution Tissue Engineering. Part A. Sep, 2014 | Pubmed ID: 24575844 High Efficiency Transfection of Embryonic Limb Mesenchyme with Plasmid DNA Using Square Wave Pulse Electroporation and Sucrose Buffer BioTechniques. 2014 | Pubmed ID: 24502798 Human Bone Marrow-derived Mesenchymal Stem Cells Display Enhanced Clonogenicity but Impaired Differentiation with Hypoxic Preconditioning Stem Cells Translational Medicine. Feb, 2014 | Pubmed ID: 24436440 Cellular Therapy in Bone-tendon Interface Regeneration Organogenesis. Jan, 2014 | Pubmed ID: 24326955 Human Mesenchymal Stem Cells Generate a Distinct Pericellular Zone of MMP Activities Via Binding of MMPs and Secretion of High Levels of TIMPs Matrix Biology : Journal of the International Society for Matrix Biology. Feb, 2014 | Pubmed ID: 24140982 Development of a Spring-Loaded Impact Device to Deliver Injurious Mechanical Impacts to the Articular Cartilage Surface Cartilage. Jan, 2013 | Pubmed ID: 26069650 Tendon and Ligament Regeneration and Repair: Clinical Relevance and Developmental Paradigm Birth Defects Research. Part C, Embryo Today : Reviews. Sep, 2013 | Pubmed ID: 24078497 Enhancement of Tenogenic Differentiation of Human Adipose Stem Cells by Tendon-derived Extracellular Matrix Biomaterials. Dec, 2013 | Pubmed ID: 24044998 The Less-often-traveled Surface of Stem Cells: Caveolin-1 and Caveolae in Stem Cells, Tissue Repair and Regeneration Stem Cell Research & Therapy. Jul, 2013 | Pubmed ID: 23899671 Three Years of Stem Cell Research & Therapy Stem Cell Research & Therapy. May, 2013 | Pubmed ID: 23635482 Effect of Parathyroid Hormone-related Protein in an in Vitro Hypertrophy Model for Mesenchymal Stem Cell Chondrogenesis International Orthopaedics. May, 2013 | Pubmed ID: 23371427 Regenerative Medicine in 2012: the Coming of Age of Musculoskeletal Tissue Engineering Nature Reviews. Rheumatology. Feb, 2013 | Pubmed ID: 23321611 Polyphenols Suppress Hydrogen Peroxide-induced Oxidative Stress in Human Bone-marrow Derived Mesenchymal Stem Cells Journal of Cellular Biochemistry. May, 2013 | Pubmed ID: 23192437 Application of Visible Light-based Projection Stereolithography for Live Cell-scaffold Fabrication with Designed Architecture Biomaterials. Jan, 2013 | Pubmed ID: 23092861 The Promise and Challenges of Stem Cell-based Therapies for Skeletal Diseases: Stem Cell Applications in Skeletal Medicine: Potential, Cell Sources and Characteristics, and Challenges of Clinical Translation BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Mar, 2013 | Pubmed ID: 22948900 Mesenchymal Progenitor Cells Derived from Traumatized Muscle Enhance Neurite Growth Journal of Tissue Engineering and Regenerative Medicine. Jun, 2013 | Pubmed ID: 22552971 Concise Review: the Clinical Application of Mesenchymal Stem Cells for Musculoskeletal Regeneration: Current Status and Perspectives Stem Cells Translational Medicine. Mar, 2012 | Pubmed ID: 23197783 Concise Review: Clinical Translation of Wound Healing Therapies Based on Mesenchymal Stem Cells Stem Cells Translational Medicine. Jan, 2012 | Pubmed ID: 23197639 Mesenchymal Stem Cell Therapy for Attenuation of Scar Formation During Wound Healing Stem Cell Research & Therapy. May, 2012 | Pubmed ID: 22668751 Stem Cell Research & Therapy in 2012 Stem Cell Research & Therapy. 2012 | Pubmed ID: 22548746 Influence of Decellularized Matrix Derived from Human Mesenchymal Stem Cells on Their Proliferation, Migration and Multi-lineage Differentiation Potential Biomaterials. Jun, 2012 | Pubmed ID: 22459197 Stem Cell- and Growth Factor-based Regenerative Therapies for Avascular Necrosis of the Femoral Head Stem Cell Research & Therapy. 2012 | Pubmed ID: 22356811 Endothelial Cell Microparticles Act As Centers of Matrix Metalloproteinsase-2 (MMP-2) Activation and Vascular Matrix Remodeling Journal of Cellular Physiology. Feb, 2012 | Pubmed ID: 21437907 Biological Responses of Human Mesenchymal Stem Cells to Titanium Wear Debris Particles Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Nov, 2011 | Pubmed ID: 22083964 Stabilization of Proteins by Nanoencapsulation in Sugar-glass for Tissue Engineering and Drug Delivery Applications Advanced Materials (Deerfield Beach, Fla.). Nov, 2011 | Pubmed ID: 21953536 Comparison of Minimally Invasive Direct Anterior Versus Posterior Total Hip Arthroplasty Based on Inflammation and Muscle Damage Markers The Journal of Bone and Joint Surgery. American Volume. Aug, 2011 | Pubmed ID: 21915544 Delayed Fracture Healing in Growth Differentiation Factor 5-deficient Mice: a Pilot Study Clinical Orthopaedics and Related Research. Oct, 2011 | Pubmed ID: 21590487 Cytokine Expression in Muscle Following Traumatic Injury Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2011 | Pubmed ID: 21452302 PTHrP Overexpression Partially Inhibits a Mechanical Strain-induced Arthritic Phenotype in Chondrocytes Osteoarthritis and Cartilage. Feb, 2011 | Pubmed ID: 21087676 Novel Strategies in Tendon and Ligament Tissue Engineering: Advanced Biomaterials and Regeneration Motifs Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology : SMARTT. Aug, 2010 | Pubmed ID: 20727171 Notochordal Cell Conditioned Medium Stimulates Mesenchymal Stem Cell Differentiation Toward a Young Nucleus Pulposus Phenotype Stem Cell Research & Therapy. 2010 | Pubmed ID: 20565707 Hypertrophy in Mesenchymal Stem Cell Chondrogenesis: Effect of TGF-beta Isoforms and Chondrogenic Conditioning Cells, Tissues, Organs. 2010 | Pubmed ID: 20407224 Potential Therapeutic Applications of Muscle-derived Mesenchymal Stem and Progenitor Cells Expert Opinion on Biological Therapy. Apr, 2010 | Pubmed ID: 20218920 Detection of Periprosthetic Infections with Use of Ribosomal RNA-based Polymerase Chain Reaction The Journal of Bone and Joint Surgery. American Volume. Mar, 2010 | Pubmed ID: 20194324 Activin A Expression Regulates Multipotency of Mesenchymal Progenitor Cells Stem Cell Research & Therapy. | Pubmed ID: 20637060 Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs Meagan J. Makarcyzk1,2, Zhong Alan Li1,3, Ilhan Yu1, Haruyo Yagi1, Xiurui Zhang1, Lauren Yocum1, Eileen Li1, Madalyn R. Fritch1, Qi Gao4, Bruce A. Bunnell5, Stuart B. Goodman4,6, Rocky S. Tuan1,8, Peter G. Alexander1,7, Hang Lin1,2,7 1Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, 2Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, 3Department of Neurobiology, University of Pittsburgh School of Medicine, 4Department of Orthopaedic Surgery, Stanford University, 5Department of Microbiology, Immunology, and Genetics, University of North Texas Health Science Center, 6Department of Bioengineering, Stanford University, 7McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 8The Chinese University of Hong Kong JoVE 64186 Bioengineering
Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs Meagan J. Makarcyzk1,2, Zhong Alan Li1,3, Ilhan Yu1, Haruyo Yagi1, Xiurui Zhang1, Lauren Yocum1, Eileen Li1, Madalyn R. Fritch1, Qi Gao4, Bruce A. Bunnell5, Stuart B. Goodman4,6, Rocky S. Tuan1,8, Peter G. Alexander1,7, Hang Lin1,2,7 1Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, 2Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, 3Department of Neurobiology, University of Pittsburgh School of Medicine, 4Department of Orthopaedic Surgery, Stanford University, 5Department of Microbiology, Immunology, and Genetics, University of North Texas Health Science Center, 6Department of Bioengineering, Stanford University, 7McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 8The Chinese University of Hong Kong JoVE 64186 Bioengineering