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Molecular Profiling von der invasiven Tumor-Microenvironment in einem 3-Dimensional Model of Colorectal Cancer Cells und

Article DOI: 10.3791/51475-v • 10:33 min • April 29th, 2014
April 29th, 2014 •
1,2, 1, 1, 1, 3, 2, 1, 1, 1,2
1Cancer Sciences Unit, University of Southampton School of Medicine, 2University Surgical Unit, University of Southampton School of Medicine, 3Bioinformatics Unit, London Research Institute, Cancer Research UK

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Molecular Profiling von Laser mikrodissektiert Zellen und Stroma aus synthetischen, Tissue-Engineering-Darmkrebs-Modelle stellt einen neuartigen Ansatz zur manipulierbaren und an der Schnittstelle zwischen Tumorzellen zu charakterisieren und zu sezieren die unverwechselbare Biologie an der invasiven Front und Krebs Stromazellen.

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Medizin Darmkrebs Krebs Metastasen organotypischen Kultur Lasermikrodissektion molekulare Profiling Invasion Tumor-Mikroumgebung Stroma Epithel Fibroblasten
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