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Journal / Bioengineering / Isolierung von Gentherapievektoren der nächsten…
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Bioengineering

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JoVE Journal Bioengineering
Isolierung von Gentherapievektoren der nächsten Generation durch Engineering, Barcoding und Screening von Kapsidvarianten des Adeno-assoziierten Virus (AAV)
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Isolierung von Gentherapievektoren der nächsten Generation durch Engineering, Barcoding und Screening von Kapsidvarianten des Adeno-assoziierten Virus (AAV)

Article DOI: 10.3791/64389-v • 09:20 min • October 18th, 2022
October 18th, 2022 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3,4,5
1Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, University of Heidelberg, 2BioQuant Center, BQ0030, University of Heidelberg, 3Cluster of Excellence CellNetworks, 4German Center for Infection Research (DZIF), 5German Center for Cardiovascular Research (DZHK)

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Generierung von AAV-Peptid-Display-Bibliotheken und anschließende Validierung durch Barcoding von Kandidaten mit neuartigen Eigenschaften für die Erstellung von AAVs der nächsten Generation.

Tags

Bioengineering Heft 188 AAV AAV-Bibliotheken Kapsid-Engineering Gentherapie Hochdurchsatz-Screening NGS Barcode-Bibliotheken
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