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Angiogenesis in the Ischemic Rat Lung
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Angiogenesis in the Ischemic Rat Lung

Angiogenesis in the Ischemic Rat Lung

DOI:
10.3791/50217-v

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07:36 min

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February 08, 2013

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,
1Johns Hopkins Asthma and Allergy Center, Division of Pulmonary and Critical Care Medicine,Johns Hopkins University

Chapters

  • 00:05Title
  • 01:46Surgical Preparaton
  • 02:45Left Pulmonary Artery Ligation
  • 05:01Left Carotid Artery Cannulation
  • 05:58Results: Bronchial Angiogenesis After Left Pulmonary Artery Ligatation
  • 07:06Conclusion

Summary

Automatic Translation

Automatic Translation

The lung is perfused by both the systemic bronchial artery and pulmonary arteries. In most lung pathologies, it is the smaller systemic vasculature that shows robust neovascularization. Cessation of pulmonary blood flow promotes brisk bronchial angiogenesis. We provide surgical details of inducing left pulmonary artery ischemia that promotes bronchial neovascularization.

Tags

AngiogenesisIschemic Rat LungPulmonary Artery ObstructionBronchial Artery ProliferationSystemic Arterial AngiogenesisNeovascularizationMicrosphere Injections

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