Andrea B. Maier Department of Gerontology and Geriatrics, Netherlands Consortium for Healthy Aging Leiden University Medical Center Biography Publications Institution JoVE Articles Andrea B. Maier has not added a biography. If you are Andrea B. Maier and would like to personalize this page please email our Author Liaison for assistance. Publications Levels of 25-hydroxyvitamin D in Familial Longevity: the Leiden Longevity Study CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. Nov, 2012 | Pubmed ID: 23128285 High Blood Pressure and Resilience to Physical and Cognitive Decline in the Oldest Old: The Leiden 85-Plus Study Journal of the American Geriatrics Society. Nov, 2012 | Pubmed ID: 23126669 CMV and Immunosenescence: from Basics to Clinics Immunity & Ageing : I & A. Oct, 2012 | Pubmed ID: 23114110 Metabolic Health in Families Enriched for Longevity is Associated with Low Prevalence of Hand Osteoarthritis and Influences OA Biomarker Profiles Annals of the Rheumatic Diseases. Oct, 2012 | Pubmed ID: 23104762 Predicting Survival in Oldest Old People The American Journal of Medicine. Sep, 2012 | Pubmed ID: 23017181 Parasitic Infections and Immune Function: Effect of Helminth Infections in a Malaria Endemic Area Immunobiology. Aug, 2012 | Pubmed ID: 22999162 Cytomegalovirus Seropositivity is Associated with Glucose Regulation in the Oldest Old. Results from the Leiden 85-plus Study Immunity & Ageing : I & A. 2012 | Pubmed ID: 22929089 Brain Tissue Volumes in Familial Longevity: the Leiden Longevity Study Aging Cell. Aug, 2012 | Pubmed ID: 22882385 Facial Appearance Reflects Human Familial Longevity and Cardiovascular Disease Risk in Healthy Individuals The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Aug, 2012 | Pubmed ID: 22879455 Muscle Characteristics in Patients with Chronic Systemic Inflammation Muscle & Nerve. Aug, 2012 | Pubmed ID: 22806369 The Effect of Chronological Age on the Inflammatory Response of Human Fibroblasts Experimental Gerontology. Sep, 2012 | Pubmed ID: 22790019 More Than Half of Hip Fracture Patients Do Not Regain Mobility in the First Postoperative Year Geriatrics & Gerontology International. Jun, 2012 | Pubmed ID: 22726959 Microarray-based Identification of Age-dependent Differences in Gene Expression of Human Dermal Fibroblasts Mechanisms of Ageing and Development. Jul, 2012 | Pubmed ID: 22721680 Do Clinical Characteristics and Outcome in Nonagenarians with a Hip Fracture Differ from Younger Patients? Geriatrics & Gerontology International. Jun, 2012 | Pubmed ID: 22686522 Lower Proportion of Naïve Peripheral CD8+ T Cells and an Unopposed Pro-inflammatory Response to Human Cytomegalovirus Proteins in Vitro Are Associated with Longer Survival in Very Elderly People Age (Dordrecht, Netherlands). Jun, 2012 | Pubmed ID: 22661297 Total Joint Replacement in the Past Does Not Relate to a Deteriorated Functional Level and Health Status in the Oldest Old Journal of Aging Research. 2012 | Pubmed ID: 22649729 The Number of P16INK4a Positive Cells in Human Skin Reflects Biological Age Aging Cell. Aug, 2012 | Pubmed ID: 22612594 Cortisol Serum Levels in Familial Longevity and Perceived Age: the Leiden Longevity Study Psychoneuroendocrinology. Oct, 2012 | Pubmed ID: 22429748 Temporal Relationship Between Handgrip Strength and Cognitive Performance in Oldest Old People Age and Ageing. Jul, 2012 | Pubmed ID: 22374646 Familial Longevity is Marked by Lower Diurnal Salivary Cortisol Levels: the Leiden Longevity Study PloS One. 2012 | Pubmed ID: 22348049 Risk Factors for Failure to Return to the Pre-fracture Place of Residence After Hip Fracture: a Prospective Longitudinal Study of 444 Patients Archives of Orthopaedic and Trauma Surgery. Jun, 2012 | Pubmed ID: 22311748 Human in Vivo Longevity is Reflected in Vitro by Differential Metabolism As Measured by (1)H-NMR Profiling of Cell Culture Supernatants Molecular BioSystems. Mar, 2012 | Pubmed ID: 22218423 [Comprehensive Geriatric Assessment: Unfeasible and Undesirable] Nederlands Tijdschrift Voor Geneeskunde. 2012 | Pubmed ID: 22217309 Spinal Reflex Properties in the Long Term After Stroke Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology. Apr, 2012 | Pubmed ID: 22196888 Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. May, 2012 | Pubmed ID: 22080500 Marked Heterogeneity in Growth Characteristics of Myoblast Clonal Cultures and Myoblast Mixed Cultures Obtained from the Same Individual Gerontology. 2012 | Pubmed ID: 21921572 Morphometric Skin Characteristics Dependent on Chronological and Biological Age: the Leiden Longevity Study Age (Dordrecht, Netherlands). Dec, 2012 | Pubmed ID: 21909657 Responsiveness of the Innate Immune System and Glucose Concentrations in the Oldest Old Age (Dordrecht, Netherlands). Aug, 2012 | Pubmed ID: 21833742 Handgrip Strength at Midlife and Familial Longevity : The Leiden Longevity Study Age (Dordrecht, Netherlands). Oct, 2012 | Pubmed ID: 21833741 Serum Triiodothyronine Levels and Inflammatory Cytokine Production Capacity Age (Dordrecht, Netherlands). Feb, 2012 | Pubmed ID: 21350816 Regenerative Potential of Human Muscle Stem Cells in Chronic Inflammation Arthritis Research & Therapy. 2011 | Pubmed ID: 22171690 High Serum Glucose Levels Are Associated with a Higher Perceived Age Age (Dordrecht, Netherlands). Nov, 2011 | Pubmed ID: 22102339 Report from the Second Cytomegalovirus and Immunosenescence Workshop Immunity & Ageing : I & A. 2011 | Pubmed ID: 22035114 Infection with Cytomegalovirus but Not Herpes Simplex Virus Induces the Accumulation of Late-differentiated CD4+ and CD8+ T-cells in Humans The Journal of General Virology. Dec, 2011 | Pubmed ID: 21813708 Accuracy of Direct Segmental Multi-frequency Bioimpedance Analysis in the Assessment of Total Body and Segmental Body Composition in Middle-aged Adult Population Clinical Nutrition (Edinburgh, Scotland). Oct, 2011 | Pubmed ID: 21555168 Homocysteine and Familial Longevity: the Leiden Longevity Study PloS One. 2011 | Pubmed ID: 21408159 C-reactive Protein and Glucose Regulation in Familial Longevity Age (Dordrecht, Netherlands). Dec, 2011 | Pubmed ID: 21246407 Functional Interplay Between Mitochondrial and Proteasome Activity in Skin Aging The Journal of Investigative Dermatology. Mar, 2011 | Pubmed ID: 21191400 An Unopposed Proinflammatory Response is Beneficial for Survival in the Oldest Old. Results of the Leiden 85-plus Study The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Apr, 2011 | Pubmed ID: 21177757 Circulating Levels of IGF1 Are Associated with Muscle Strength in Middle-aged- and Oldest-old Women European Journal of Endocrinology / European Federation of Endocrine Societies. Feb, 2011 | Pubmed ID: 21135066 Relation Between Maximum Replicative Capacity and Oxidative Stress-induced Responses in Human Skin Fibroblasts in Vitro The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jan, 2011 | Pubmed ID: 20937674 Higher Blood Pressure is Associated with Higher Handgrip Strength in the Oldest Old American Journal of Hypertension. Jan, 2011 | Pubmed ID: 20814409 Hallmark Features of Immunosenescence Are Absent in Familial Longevity Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010 | Pubmed ID: 20855876 Immunosenescence and Cytomegalovirus: Where Do We Stand After a Decade? Immunity & Ageing : I & A. 2010 | Pubmed ID: 20822513 Trajectories of Disability in the Last Year of Life The New England Journal of Medicine. Jul, 2010 | Pubmed ID: 20665928 Patterns of Muscle Strength Loss with Age in the General Population and Patients with a Chronic Inflammatory State Ageing Research Reviews. Oct, 2010 | Pubmed ID: 20553969 Handgrip Strength As a Predictor of Functional, Psychological and Social Health. A Prospective Population-based Study Among the Oldest Old Age and Ageing. May, 2010 | Pubmed ID: 20219767 Handgrip Strength and Mortality in the Oldest Old Population: the Leiden 85-plus Study CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. Mar, 2010 | Pubmed ID: 20142372 Rapid Flow Cytometric Method for Measuring Senescence Associated Beta-galactosidase Activity in Human Fibroblasts Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2009 | Pubmed ID: 19777541 Stress-induced Responses of Human Skin Fibroblasts in Vitro Reflect Human Longevity Aging Cell. Sep, 2009 | Pubmed ID: 19681808 Relation Between Replicative Senescence of Human Fibroblasts and Life History Characteristics Ageing Research Reviews. Jul, 2009 | Pubmed ID: 19491042 Colony Formation and Colony Size Do Not Reflect the Onset of Replicative Senescence in Human Fibroblasts The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jul, 2008 | Pubmed ID: 18693218 Influence of the TP53 Codon 72 Polymorphism on the Cellular Responses to X-irradiation in Fibroblasts from Nonagenarians Mechanisms of Ageing and Development. Apr, 2008 | Pubmed ID: 18272203 Relation Between Body Height and Replicative Capacity of Human Fibroblasts in Nonagenarians The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jan, 2008 | Pubmed ID: 18245759 High Prevalence of Cytomegalovirus DNA in Plasma Samples of Blood Donors in Connection with Seroconversion Transfusion. Nov, 2007 | Pubmed ID: 17958525 Beta-galactosidase Activity As a Biomarker of Replicative Senescence During the Course of Human Fibroblast Cultures Annals of the New York Academy of Sciences. Apr, 2007 | Pubmed ID: 17460195 Persistence of High-replicative Capacity in Cultured Fibroblasts from Nonagenarians Aging Cell. Feb, 2007 | Pubmed ID: 17266674 Monitoring of Ubiquitin-proteasome Activity in Living Cells Using a Degron (dgn)-destabilized Green Fluorescent Protein (GFP)-based Reporter Protein Ruth Greussing1, Hermann Unterluggauer1, Rafal Koziel1, Andrea B. Maier2, Pidder Jansen-Dürr1 1Molecular and Cell Biology, Institute for Biomedical Aging Research, 2Department of Gerontology and Geriatrics, Netherlands Consortium for Healthy Aging, Leiden University Medical Center JoVE 3327 Biology
Monitoring of Ubiquitin-proteasome Activity in Living Cells Using a Degron (dgn)-destabilized Green Fluorescent Protein (GFP)-based Reporter Protein Ruth Greussing1, Hermann Unterluggauer1, Rafal Koziel1, Andrea B. Maier2, Pidder Jansen-Dürr1 1Molecular and Cell Biology, Institute for Biomedical Aging Research, 2Department of Gerontology and Geriatrics, Netherlands Consortium for Healthy Aging, Leiden University Medical Center JoVE 3327 Biology