Ashley T. Haase Department of Microbiology, Medical School University of Minnesota Biography Publications Institution JoVE Articles Ashley T. Haase has not added a biography. If you are Ashley T. Haase and would like to personalize this page please email our Author Liaison for assistance. Publications Lymphoid Tissue Damage in HIV-1 Infection Depletes Naïve T Cells and Limits T Cell Reconstitution After Antiretroviral Therapy PLoS Pathogens. Jan, 2012 | Pubmed ID: 22241988 The Immunosuppressive Role of IL-32 in Lymphatic Tissue During HIV-1 Infection Journal of Immunology (Baltimore, Md. : 1950). Jun, 2011 | Pubmed ID: 21525393 Cumulative Mechanisms of Lymphoid Tissue Fibrosis and T Cell Depletion in HIV-1 and SIV Infections The Journal of Clinical Investigation. Mar, 2011 | Pubmed ID: 21393864 Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions Annual Review of Medicine. Feb, 2011 | Pubmed ID: 21054171 Differences in HIV Burden and Immune Activation Within the Gut of HIV-positive Patients Receiving Suppressive Antiretroviral Therapy The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20939732 Host Genes Associated with HIV-1 Replication in Lymphatic Tissue Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010 | Pubmed ID: 20935203 Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections PLoS Pathogens. 2010 | Pubmed ID: 20808901 A Role for Syndecan-1 and Claudin-2 in Microbial Translocation During HIV-1 Infection Journal of Acquired Immune Deficiency Syndromes (1999). Nov, 2010 | Pubmed ID: 20700059 AIDS and Optic Neuritis in a Rhesus Monkey Infected with the R5 Clade C SHIV-1157ipd3N4 Journal of Medical Primatology. Oct, 2010 | Pubmed ID: 20412378 Targeting Early Infection to Prevent HIV-1 Mucosal Transmission Nature. Mar, 2010 | Pubmed ID: 20220840 Global Genomic Analysis Reveals Rapid Control of a Robust Innate Response in SIV-infected Sooty Mangabeys The Journal of Clinical Investigation. Dec, 2009 | Pubmed ID: 19959874 Microarray Analysis of Lymphatic Tissue Reveals Stage-specific, Gene Expression Signatures in HIV-1 Infection Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009 | Pubmed ID: 19596987 Simultaneous Cell-to-cell Transmission of Human Immunodeficiency Virus to Multiple Targets Through Polysynapses Journal of Virology. Jun, 2009 | Pubmed ID: 19369333 Visualizing Antigen-specific and Infected Cells in Situ Predicts Outcomes in Early Viral Infection Science (New York, N.Y.). Mar, 2009 | Pubmed ID: 19325114 Glycerol Monolaurate Prevents Mucosal SIV Transmission Nature. Apr, 2009 | Pubmed ID: 19262509 Glycerol Monolaurate Does Not Alter Rhesus Macaque (Macaca Mulatta) Vaginal Lactobacilli and is Safe for Chronic Use Antimicrobial Agents and Chemotherapy. Dec, 2008 | Pubmed ID: 18838587 Collagen Deposition Limits Immune Reconstitution in the Gut The Journal of Infectious Diseases. Aug, 2008 | Pubmed ID: 18598193 The Role of Collagen Deposition in Depleting CD4+ T Cells and Limiting Reconstitution in HIV-1 and SIV Infections Through Damage to the Secondary Lymphoid Organ Niche Seminars in Immunology. Jun, 2008 | Pubmed ID: 18595731 Availability of Activated CD4+ T Cells Dictates the Level of Viremia in Naturally SIV-infected Sooty Mangabeys The Journal of Clinical Investigation. Jun, 2008 | Pubmed ID: 18497876 Early Resolution of Acute Immune Activation and Induction of PD-1 in SIV-infected Sooty Mangabeys Distinguishes Nonpathogenic from Pathogenic Infection in Rhesus Macaques Journal of Immunology (Baltimore, Md. : 1950). May, 2008 | Pubmed ID: 18453600 Genital Ulcers Facilitate Rapid Viral Entry and Dissemination Following Intravaginal Inoculation with Cell-associated Simian Immunodeficiency Virus SIVmac239 Journal of Virology. Apr, 2008 | Pubmed ID: 18272571 Short-lived Infected Cells Support Virus Replication in Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus: Implications for AIDS Pathogenesis Journal of Virology. Apr, 2008 | Pubmed ID: 18216113 Simian Immunodeficiency Virus-induced Intestinal Cell Apoptosis is the Underlying Mechanism of the Regenerative Enteropathy of Early Infection The Journal of Infectious Diseases. Feb, 2008 | Pubmed ID: 18199035 Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice PLoS Medicine. Jan, 2008 | Pubmed ID: 18198941 Introduction from the Co-Chairmen of the US and Japanese Delegation of the US-Japan Cooperative Medical Science Program Tuberculosis (Edinburgh, Scotland). Aug, 2007 | Pubmed ID: 17646134 Intrarectal Transmission, Systemic Infection, and CD4+ T Cell Depletion in Humanized Mice Infected with HIV-1 The Journal of Experimental Medicine. Apr, 2007 | Pubmed ID: 17389241 Simian Immunodeficiency Virus-induced Lymphatic Tissue Fibrosis is Mediated by Transforming Growth Factor Beta 1-positive Regulatory T Cells and Begins in Early Infection The Journal of Infectious Diseases. Feb, 2007 | Pubmed ID: 17230415 Humanized Mice Mount Specific Adaptive and Innate Immune Responses to EBV and TSST-1 Nature Medicine. Nov, 2006 | Pubmed ID: 17057712 Gene Expression Alterations in Brains of Mice Infected with Three Strains of Scrapie BMC Genomics. 2006 | Pubmed ID: 16700923 Lymphatic Tissue Fibrosis is Associated with Reduced Numbers of Naive CD4+ T Cells in Human Immunodeficiency Virus Type 1 Infection Clinical and Vaccine Immunology : CVI. May, 2006 | Pubmed ID: 16682476 Premature Induction of an Immunosuppressive Regulatory T Cell Response During Acute Simian Immunodeficiency Virus Infection The Journal of Infectious Diseases. Mar, 2006 | Pubmed ID: 16453267 In Situ Staining Using MHC Class I Tetramers Current Protocols in Immunology / Edited by John E. Coligan ... [et Al.]. Jan, 2005 | Pubmed ID: 18432944 Amount of Lymphatic Tissue Fibrosis in HIV Infection Predicts Magnitude of HAART-associated Change in Peripheral CD4 Cell Count AIDS (London, England). Dec, 2005 | Pubmed ID: 16284469 Perils at Mucosal Front Lines for HIV and SIV and Their Hosts Nature Reviews. Immunology. Oct, 2005 | Pubmed ID: 16200081 Potential Roles of Follicular Dendritic Cell-associated Osteopontin in Lymphoid Follicle Pathology and Repair and in B Cell Regulation in HIV-1 and SIV Infection The Journal of Infectious Diseases. Oct, 2005 | Pubmed ID: 16136472 Propagation and Dissemination of Infection After Vaginal Transmission of Simian Immunodeficiency Virus Journal of Virology. Jul, 2005 | Pubmed ID: 15994816 Peak SIV Replication in Resting Memory CD4+ T Cells Depletes Gut Lamina Propria CD4+ T Cells Nature. Apr, 2005 | Pubmed ID: 15793562 CD4+ T Cell Depletion During All Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract The Journal of Experimental Medicine. Sep, 2004 | Pubmed ID: 15365096 Roles of Substrate Availability and Infection of Resting and Activated CD4+ T Cells in Transmission and Acute Simian Immunodeficiency Virus Infection Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004 | Pubmed ID: 15064398 Functional Genomic Analysis of the Response of HIV-1-infected Lymphatic Tissue to Antiretroviral Therapy The Journal of Infectious Diseases. Feb, 2004 | Pubmed ID: 14767808 Transmission, Acute HIV-1 Infection and the Quest for Strategies to Prevent Infection Nature Medicine. Jul, 2003 | Pubmed ID: 12835704 Collagen Deposition in HIV-1 Infected Lymphatic Tissues and T Cell Homeostasis The Journal of Clinical Investigation. Oct, 2002 | Pubmed ID: 12393849 Persistent Abnormalities in Lymphoid Tissues of Human Immunodeficiency Virus-infected Patients Successfully Treated with Highly Active Antiretroviral Therapy The Journal of Infectious Diseases. Oct, 2002 | Pubmed ID: 12355359 In Situ Tetramer Staining Journal of Immunological Methods. Oct, 2002 | Pubmed ID: 12213340 A Technique to Simultaneously Visualize Virus-Specific CD8+ T Cells and Virus-Infected Cells In situ Qingsheng Li1, Pamela J. Skinner2, Lijie Duan1, Ashley T. Haase1 1Department of Microbiology, Medical School, University of Minnesota, 2Department of Veterinary and Biomedical Sciences, University of Minnesota JoVE 1561 Biology
A Technique to Simultaneously Visualize Virus-Specific CD8+ T Cells and Virus-Infected Cells In situ Qingsheng Li1, Pamela J. Skinner2, Lijie Duan1, Ashley T. Haase1 1Department of Microbiology, Medical School, University of Minnesota, 2Department of Veterinary and Biomedical Sciences, University of Minnesota JoVE 1561 Biology