Christopher J. Brown Biography Publications JoVE Articles Christopher J. Brown has not added a biography. If you are Christopher J. Brown and would like to personalize this page please email our Author Liaison for assistance. Publications Simultaneous Measurement of P53:Mdm2 and P53:Mdm4 Protein-protein Interactions in Whole Cells Using Fluorescence Labelled Foci Scientific Reports. Nov, 2019 | Pubmed ID: 31784573 Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties Molecules (Basel, Switzerland). Jun, 2019 | Pubmed ID: 31226791 Monitoring Flux in Signalling Pathways Through Measurements of 4EBP1-mediated EIF4F Complex Assembly BMC Biology. 05, 2019 | Pubmed ID: 31118010 Structural Insights Reveal a Recognition Feature for Tailoring Hydrocarbon Stapled-peptides Against the Eukaryotic Translation Initiation Factor 4E Protein Chemical Science. Feb, 2019 | Pubmed ID: 30881679 Enhancing Specific Disruption of Intracellular Protein Complexes by Hydrocarbon Stapled Peptides Using Lipid Based Delivery Scientific Reports. 05, 2017 | Pubmed ID: 28496125 Stapled Peptides with Improved Potency and Specificity That Activate P53 ACS Chemical Biology. Mar, 2013 | Pubmed ID: 23214419 C-terminal Substitution of MDM2 Interacting Peptides Modulates Binding Affinity by Distinctive Mechanisms PloS One. 2011 | Pubmed ID: 21904608 Stabilizing the EIF4G1 α-helix Increases Its Binding Affinity with EIF4E: Implications for Peptidomimetic Design Strategies Journal of Molecular Biology. Jan, 2011 | Pubmed ID: 21094167 Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells Yuri Frosi, Siti Radhiah Ramlan, Christopher J. Brown 1p53 Laboratory, Neuros/Immunos, A*STAR (Agency for Science, Technology and Research) JoVE 60850 Cancer Research
Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells Yuri Frosi, Siti Radhiah Ramlan, Christopher J. Brown 1p53 Laboratory, Neuros/Immunos, A*STAR (Agency for Science, Technology and Research) JoVE 60850 Cancer Research