Deborah DeRyckere Department of Pediatrics University of Colorado Anschutz Medical Campus Biography Publications Institution JoVE Articles Deborah DeRyckere has not added a biography. If you are Deborah DeRyckere and would like to personalize this page please email our Author Liaison for assistance. Publications UNC569, a Novel Small Molecule Mer Inhibitor with Efficacy Against Acute Lymphoblastic Leukemia in Vitro and in Vivo Molecular Cancer Therapeutics. Aug, 2013 | Pubmed ID: 23997116 MerTK Inhibition in Tumor Leukocytes Decreases Tumor Growth and Metastasis The Journal of Clinical Investigation. Aug, 2013 | Pubmed ID: 23867499 Mer Receptor Tyrosine Kinase is a Therapeutic Target in Pre-B-cell Acute Lymphoblastic Leukemia Blood. Aug, 2013 | Pubmed ID: 23861246 Molecular Pathways: MERTK Signaling in Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2013 | Pubmed ID: 23833304 UNC1062, a New and Potent Mer Inhibitor European Journal of Medicinal Chemistry. Jul, 2013 | Pubmed ID: 23693152 MERTK Receptor Tyrosine Kinase is a Therapeutic Target in Melanoma The Journal of Clinical Investigation. May, 2013 | Pubmed ID: 23585477 Bioluminescence Imaging of Leukemia Cell Lines in Vitro and in Mouse Xenografts: Effects of Monoclonal and Polyclonal Cell Populations on Intensity and Kinetics of Photon Emission Journal of Hematology & Oncology. 2013 | Pubmed ID: 23343252 Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia ACS Medicinal Chemistry Letters. Feb, 2012 | Pubmed ID: 22662287 Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus PloS One. 2012 | Pubmed ID: 22363695 Vandetanib Mediates Anti-leukemia Activity by Multiple Mechanisms and Interacts Synergistically with DNA Damaging Agents Investigational New Drugs. Apr, 2012 | Pubmed ID: 21046425 Mer Receptor Tyrosine Kinase is a Novel Therapeutic Target in Pediatric B-cell Acute Lymphoblastic Leukemia Blood. Sep, 2009 | Pubmed ID: 19643988 E2F1 and E2F2 Are Differentially Required for Homeostasis-driven and Antigen-induced T Cell Proliferation in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2005 | Pubmed ID: 16002659 Characterization of Transcriptional Regulation During Negative Selection in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2003 | Pubmed ID: 12847248 Identification and Characterization of Transcription Factor Target Genes Using Gene-targeted Mice Methods (San Diego, Calif.). Jan, 2002 | Pubmed ID: 12054905 Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia Sandra Christoph1,2, Alisa B. Lee-Sherick1, Susan Sather1, Deborah DeRyckere1, Douglas K. Graham1 1Department of Pediatrics, University of Colorado Anschutz Medical Campus, 2Department of Bone Marrow Transplantation, University Hospital of Essen JoVE 50720 Medicine
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia Sandra Christoph1,2, Alisa B. Lee-Sherick1, Susan Sather1, Deborah DeRyckere1, Douglas K. Graham1 1Department of Pediatrics, University of Colorado Anschutz Medical Campus, 2Department of Bone Marrow Transplantation, University Hospital of Essen JoVE 50720 Medicine