Dennis K. Ninaber PulmoScience Laboratory, Department of Pulmonology Leiden University Medical Center Biography Publications Institution JoVE Articles Dennis K. Ninaber has not added a biography. If you are Dennis K. Ninaber and would like to personalize this page please email our Author Liaison for assistance. Publications R-Propranolol Has Broad-Spectrum Anti-Coronavirus Activity and Suppresses Factors Involved in Pathogenic Angiogenesis International Journal of Molecular Sciences. Feb, 2023 | Pubmed ID: 36902020 Cigarette Smoke Impairs Airway Epithelial Wound Repair: Role of Modulation of Epithelial-Mesenchymal Transition Processes and Notch-1 Signaling Antioxidants (Basel, Switzerland). Oct, 2022 | Pubmed ID: 36290742 Early Transcriptional Responses of Bronchial Epithelial Cells to Whole Cigarette Smoke Mirror Those of In-vivo Exposed Human Bronchial Mucosa Respiratory Research. Sep, 2022 | Pubmed ID: 36056356 Dysregulated Mitochondrial Metabolism Upon Cigarette Smoke Exposure in Various Human Bronchial Epithelial Cell Models Disease Models & Mechanisms. Mar, 2022 | Pubmed ID: 35344036 Disease Modeling Following Organoid-based Expansion of Airway Epithelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2021 | Pubmed ID: 34378410 Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production Via Multiple Mechanisms in Differentiated Airway Epithelial Cells Frontiers in Cellular and Infection Microbiology. 2020 | Pubmed ID: 32637364 Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle Antimicrobial Agents and Chemotherapy. Jul, 2020 | Pubmed ID: 32513797 In Vitro Modelling of Alveolar Repair at the Air-liquid Interface Using Alveolar Epithelial Cells Derived from Human Induced Pluripotent Stem Cells Scientific Reports. Mar, 2020 | Pubmed ID: 32218519 TGF-β1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms Journal of Innate Immunity. 2020 | Pubmed ID: 30970352 Aberrant Epithelial Differentiation by Cigarette Smoke Dysregulates Respiratory Host Defence The European Respiratory Journal. Apr, 2018 | Pubmed ID: 29545277 Farm Dust Reduces Viral Load in Human Bronchial Epithelial Cells by Increasing Barrier Function and Antiviral Responses The Journal of Allergy and Clinical Immunology. May, 2018 | Pubmed ID: 29425849 Effect of Diesel Exhaust Generated by a City Bus Engine on Stress Responses and Innate Immunity in Primary Bronchial Epithelial Cell Cultures Toxicology in Vitro : an International Journal Published in Association with BIBRA. Apr, 2018 | Pubmed ID: 29408669 Cigarette Smoke Differentially Affects IL-13-induced Gene Expression in Human Airway Epithelial Cells Physiological Reports. Jul, 2017 | Pubmed ID: 28701525 Proinflammatory Cytokines Impair Vitamin D-Induced Host Defense in Cultured Airway Epithelial Cells American Journal of Respiratory Cell and Molecular Biology. Jun, 2017 | Pubmed ID: 28231019 Metabolic Engineering Toward Sustainable Production of Nylon-6 ACS Synthetic Biology. Jan, 2016 | Pubmed ID: 26511532 Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25320088 Deubiquitinase Function of Arterivirus Papain-like Protease 2 Suppresses the Innate Immune Response in Infected Host Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23401522 Arterivirus and Nairovirus Ovarian Tumor Domain-containing Deubiquitinases Target Activated RIG-I to Control Innate Immune Signaling Journal of Virology. Jan, 2012 | Pubmed ID: 22072774 IL-4 and IL-13 Exposure During Mucociliary Differentiation of Bronchial Epithelial Cells Increases Antimicrobial Activity and Expression of Antimicrobial Peptides Respiratory Research. May, 2011 | Pubmed ID: 21529380 Epithelial Differentiation is a Determinant in the Production of Eotaxin-2 and -3 by Bronchial Epithelial Cells in Response to IL-4 and IL-13 Molecular Immunology. Feb, 2007 | Pubmed ID: 16740309 The Antimicrobial Peptide LL-37 Enhances IL-8 Release by Human Airway Smooth Muscle Cells The Journal of Allergy and Clinical Immunology. Jun, 2006 | Pubmed ID: 16750994 Human Cathelicidin LL-37 is a Chemoattractant for Eosinophils and Neutrophils That Acts Via Formyl-peptide Receptors International Archives of Allergy and Immunology. 2006 | Pubmed ID: 16557028 Host Defense Effector Molecules in Mucosal Secretions FEMS Immunology and Medical Microbiology. Aug, 2005 | Pubmed ID: 16051067 The Antimicrobial Peptide LL-37 Activates Innate Immunity at the Airway Epithelial Surface by Transactivation of the Epidermal Growth Factor Receptor Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003 | Pubmed ID: 14662872 Isolating Bronchial Epithelial Cells from Resected Lung Tissue for Biobanking and Establishing Well-Differentiated Air-Liquid Interface Cultures Dennis K. Ninaber1, Anne M. van der Does1, Pieter S. Hiemstra1 1PulmoScience Laboratory, Department of Pulmonology, Leiden University Medical Center JoVE 65102 Immunology and Infection
Isolating Bronchial Epithelial Cells from Resected Lung Tissue for Biobanking and Establishing Well-Differentiated Air-Liquid Interface Cultures Dennis K. Ninaber1, Anne M. van der Does1, Pieter S. Hiemstra1 1PulmoScience Laboratory, Department of Pulmonology, Leiden University Medical Center JoVE 65102 Immunology and Infection