Gregory L. Brower Department of Cell Biology and Anatomy University of South Carolina- School of Medicine Biography Publications Institution JoVE Articles Gregory L. Brower has not added a biography. If you are Gregory L. Brower and would like to personalize this page please email our Author Liaison for assistance. Publications Estrogenic Modulation of Inflammation-related Genes in Male Rats Following Volume Overload Physiological Genomics. Jan, 2012 | Pubmed ID: 22274565 Tryptase/Protease-activated Receptor 2 Interactions Induce Selective Mitogen-activated Protein Kinase Signaling and Collagen Synthesis by Cardiac Fibroblasts Hypertension. Aug, 2011 | Pubmed ID: 21730297 Cardiac Mast Cells: the Centrepiece in Adverse Myocardial Remodelling Cardiovascular Research. Jan, 2011 | Pubmed ID: 20736239 Temporal Evaluation of Cardiac Myocyte Hypertrophy and Hyperplasia in Male Rats Secondary to Chronic Volume Overload The American Journal of Pathology. Sep, 2010 | Pubmed ID: 20651227 Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats Hypertension. Aug, 2010 | Pubmed ID: 20606113 Inhibition of Matrix Metalloproteinase Activity Prevents Increases in Myocardial Tumor Necrosis Factor-alpha Journal of Molecular and Cellular Cardiology. Aug, 2010 | Pubmed ID: 20403361 Sympathetic Nervous System Modulation of Inflammation and Remodeling in the Hypertensive Heart Hypertension. Feb, 2010 | Pubmed ID: 20048196 Estrogen Attenuates Chronic Volume Overload Induced Structural and Functional Remodeling in Male Rat Hearts American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2010 | Pubmed ID: 19933421 TNF-alpha Inhibition Attenuates Adverse Myocardial Remodeling in a Rat Model of Volume Overload American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2009 | Pubmed ID: 19666842 Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2009 | Pubmed ID: 19592468 ETA Selective Receptor Antagonism Prevents Ventricular Remodeling in Volume-overloaded Rats American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2009 | Pubmed ID: 19429817 Cardiac Mast Cells Mediate Left Ventricular Fibrosis in the Hypertensive Rat Heart Hypertension. Jun, 2009 | Pubmed ID: 19398662 Regulation of Matrix Metalloproteinases is at the Heart of Myocardial Remodeling American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2008 | Pubmed ID: 18757475 Protection from Adverse Myocardial Remodeling Secondary to Chronic Volume Overload in Mast Cell Deficient Rats Journal of Molecular and Cellular Cardiology. Jul, 2008 | Pubmed ID: 18538342 Defective Intracellular Ca2+ Homeostasis Contributes to Myocyte Dysfunction During Ventricular Remodelling Induced by Chronic Volume Overload in Rats Clinical and Experimental Pharmacology & Physiology. Jul, 2008 | Pubmed ID: 18346170 Effects of Nonselective Endothelin-1 Receptor Antagonism on Cardiac Mast Cell-mediated Ventricular Remodeling in Rats American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2008 | Pubmed ID: 18178727 Cardioprotection in Female Rats Subjected to Chronic Volume Overload: Synergistic Interaction of Estrogen and Phytoestrogens American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2008 | Pubmed ID: 17965290 Response of Cardiac Mast Cells to Atrial Natriuretic Peptide American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2007 | Pubmed ID: 17434981 Inhibition of Matrix Metalloproteinase Activity by ACE Inhibitors Prevents Left Ventricular Remodeling in a Rat Model of Heart Failure American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2007 | Pubmed ID: 17308006 The Relationship Between Myocardial Extracellular Matrix Remodeling and Ventricular Function European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Oct, 2006 | Pubmed ID: 16935520 Cardiac Mast Cell Regulation of Matrix Metalloproteinase-related Ventricular Remodeling in Chronic Pressure or Volume Overload Cardiovascular Research. Feb, 2006 | Pubmed ID: 16376324 Pharmacologic Inhibition of Mast Cell Degranulation Prevents Left Ventricular Remodeling Induced by Chronic Volume Overload in Rats Journal of Cardiac Failure. Sep, 2005 | Pubmed ID: 16198252 Effects of Dietary Phytoestrogens on Cardiac Remodeling Secondary to Chronic Volume Overload in Female Rats Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2005 | Pubmed ID: 15961607 Modulation of Cardiac Mast Cell-mediated Extracellular Matrix Degradation by Estrogen American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2005 | Pubmed ID: 15722408 Endothelin-1 Mediates Cardiac Mast Cell Degranulation, Matrix Metalloproteinase Activation, and Myocardial Remodeling in Rats American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2004 | Pubmed ID: 15231495 The Dynamic Interaction Between Matrix Metalloproteinase Activity and Adverse Myocardial Remodeling Heart Failure Reviews. Jan, 2004 | Pubmed ID: 14739766 Gender Mediated Cardiac Protection from Adverse Ventricular Remodeling is Abolished by Ovariectomy Molecular and Cellular Biochemistry. Sep, 2003 | Pubmed ID: 14575309 Cardiac Mast Cell- and Chymase-mediated Matrix Metalloproteinase Activity and Left Ventricular Remodeling in Mitral Regurgitation in the Dog Journal of Molecular and Cellular Cardiology. Mar, 2003 | Pubmed ID: 12676546 The Role of Myocardial Fibrillar Collagen in Ventricular Remodeling and Function Journal of Cardiac Failure. Dec, 2002 | Pubmed ID: 12555139 Cause and Effect Relationship Between Myocardial Mast Cell Number and Matrix Metalloproteinase Activity American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2002 | Pubmed ID: 12124196 Gender Differences in Cardiac Remodeling Secondary to Chronic Volume Overload Journal of Cardiac Failure. Apr, 2002 | Pubmed ID: 12016634 Cardiac Mast Cell-mediated Activation of Gelatinase and Alteration of Ventricular Diastolic Function American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2002 | Pubmed ID: 12003823 Effects of Matrix Metalloproteinase Inhibition on Ventricular Remodeling Due to Volume Overload Circulation. Apr, 2002 | Pubmed ID: 11997287 Effects of Mast Cells on the Behavior of Isolated Heart Fibroblasts: Modulation of Collagen Remodeling and Gene Expression Journal of Cellular Physiology. Apr, 2002 | Pubmed ID: 11920681 Isolation of Functional Cardiac Immune Cells Jennifer L. McLarty1, Giselle C. Meléndez1, William J. Spencer1, Scott P. Levick1, Gregory L. Brower1, Joseph S. Janicki1 1Department of Cell Biology and Anatomy, University of South Carolina- School of Medicine JoVE 3020 Immunology and Infection
Isolation of Functional Cardiac Immune Cells Jennifer L. McLarty1, Giselle C. Meléndez1, William J. Spencer1, Scott P. Levick1, Gregory L. Brower1, Joseph S. Janicki1 1Department of Cell Biology and Anatomy, University of South Carolina- School of Medicine JoVE 3020 Immunology and Infection