Henry Fechner Department of Applied Biochemistry Institute of Biotechnology, Berlin University of Technology Biography Publications Institution JoVE Articles Henry Fechner has not added a biography. If you are Henry Fechner and would like to personalize this page please email our Author Liaison for assistance. Publications MicroRNA-regulated Viral Vectors for Gene Therapy World Journal of Experimental Medicine. May, 2016 | Pubmed ID: 27226955 Biological Antivirals for Treatment of Adenovirus Infections Antiviral Therapy. Apr, 2016 | Pubmed ID: 27032991 The Coxsackievirus and Adenovirus Receptor: Glycosylation and the Extracellular D2 Domain Are Not Required for Coxsackievirus B3 Infection Journal of Virology. Jun, 2016 | Pubmed ID: 27030267 Application of Modified Antisense Oligonucleotides and SiRNAs As Antiviral Drugs Future Medicinal Chemistry. 2015 | Pubmed ID: 26381598 Use of a Three-dimensional Humanized Liver Model for the Study of Viral Gene Vectors Journal of Biotechnology. Oct, 2015 | Pubmed ID: 26356676 Enhanced Suppression of Adenovirus Replication by Triple Combination of Anti-adenoviral SiRNAs, Soluble Adenovirus Receptor Trap SCAR-Fc and Cidofovir Antiviral Research. Aug, 2015 | Pubmed ID: 26026665 Impaired Endothelial Regeneration Through Human Parvovirus B19-Infected Circulating Angiogenic Cells in Patients With Cardiomyopathy The Journal of Infectious Diseases. Oct, 2015 | Pubmed ID: 25805750 Combination of RNA Interference and Virus Receptor Trap Exerts Additive Antiviral Activity in Coxsackievirus B3-induced Myocarditis in Mice The Journal of Infectious Diseases. Feb, 2015 | Pubmed ID: 25193982 Antibody-mediated Enhancement of Parvovirus B19 Uptake into Endothelial Cells Mediated by a Receptor for Complement Factor C1q Journal of Virology. Jul, 2014 | Pubmed ID: 24807719 Interspecies Differences in Virus Uptake Versus Cardiac Function of the Coxsackievirus and Adenovirus Receptor Journal of Virology. Jul, 2014 | Pubmed ID: 24741103 A Novel Artificial MicroRNA Expressing AAV Vector for Phospholamban Silencing in Cardiomyocytes Improves Ca2+ Uptake into the Sarcoplasmic Reticulum PloS One. 2014 | Pubmed ID: 24670775 A Novel Method for the Quantification of Adeno-associated Virus Vectors for RNA Interference Applications Using Quantitative Polymerase Chain Reaction and Purified Genomic Adeno-associated Virus DNA As a Standard Human Gene Therapy Methods. Dec, 2013 | Pubmed ID: 23987130 Adenovirus Vector-mediated RNA Interference for the Inhibition of Human Parvovirus B19 Replication Virus Research. Sep, 2013 | Pubmed ID: 23770153 Application of Mutated MiR-206 Target Sites Enables Skeletal Muscle-specific Silencing of Transgene Expression of Cardiotropic AAV9 Vectors Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2013 | Pubmed ID: 23439498 Roles of E4orf6 and VA I RNA in Adenovirus-mediated Stimulation of Human Parvovirus B19 DNA Replication and Structural Gene Expression Journal of Virology. May, 2012 | Pubmed ID: 22357277 Pharmacological and Biological Antiviral Therapeutics for Cardiac Coxsackievirus Infections Molecules (Basel, Switzerland). Oct, 2011 | Pubmed ID: 21989310 Virus-host Coevolution in a Persistently Coxsackievirus B3-infected Cardiomyocyte Cell Line Journal of Virology. Dec, 2011 | Pubmed ID: 21976640 Transactivation of Human Parvovirus B19 Gene Expression in Endothelial Cells by Adenoviral Helper Functions Virology. Mar, 2011 | Pubmed ID: 21236463 Decreased Cardiac SERCA2 Expression, SR Ca Uptake, and Contractile Function in Hypothyroidism Are Attenuated in SERCA2 Overexpressing Transgenic Rats American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2011 | Pubmed ID: 21217071 Vaccine Protection Against Lethal Homologous and Heterologous Challenge Using Recombinant AAV Vectors Expressing Codon-optimized Genes from Pandemic Swine Origin Influenza Virus (SOIV) Vaccine. Feb, 2011 | Pubmed ID: 21195079 Efficient Melanoma Cell Killing and Reduced Melanoma Growth in Mice by a Selective Replicating Adenovirus Armed with Tumor Necrosis Factor-related Apoptosis-inducing Ligand Human Gene Therapy. Apr, 2011 | Pubmed ID: 20977303 Matricellular Signaling Molecule CCN1 Attenuates Experimental Autoimmune Myocarditis by Acting As a Novel Immune Cell Migration Modulator Circulation. Dec, 2010 | Pubmed ID: 21135363 Inhibition of Adenovirus Infections by SiRNA-mediated Silencing of Early and Late Adenoviral Gene Functions Antiviral Research. Oct, 2010 | Pubmed ID: 20708037 Rapid Construction of Adeno-associated Virus Vectors Expressing Multiple Short Hairpin RNAs with High Antiviral Activity Against Echovirus 30 Oligonucleotides. Aug, 2010 | Pubmed ID: 20649454 Cardiac-targeted Delivery of Regulatory RNA Molecules and Genes for the Treatment of Heart Failure Cardiovascular Research. Jun, 2010 | Pubmed ID: 20176815 Mismatch Repair System Decreases Cell Survival by Stabilizing the Tetraploid G1 Arrest in Response to SN-38 International Journal of Cancer. Jun, 2010 | Pubmed ID: 19739070 Efficient and Selective Tumor Cell Lysis and Induction of Apoptosis in Melanoma Cells by a Conditional Replication-competent CD95L Adenovirus Experimental Dermatology. Aug, 2010 | Pubmed ID: 19725869 Prevention of Cardiac Dysfunction in Acute Coxsackievirus B3 Cardiomyopathy by Inducible Expression of a Soluble Coxsackievirus-adenovirus Receptor Circulation. Dec, 2009 | Pubmed ID: 19933937 Combination of Soluble Coxsackievirus-adenovirus Receptor and Anti-coxsackievirus SiRNAs Exerts Synergistic Antiviral Activity Against Coxsackievirus B3 Antiviral Research. Sep, 2009 | Pubmed ID: 19591879 Long-term Cardiac-targeted RNA Interference for the Treatment of Heart Failure Restores Cardiac Function and Reduces Pathological Hypertrophy Circulation. Mar, 2009 | Pubmed ID: 19237664 Inhibition of Picornaviruses by Means of RNA Interference Nucleic Acids Symposium Series (2004). 2008 | Pubmed ID: 18776254 Cardiac-targeted RNA Interference Mediated by an AAV9 Vector Improves Cardiac Function in Coxsackievirus B3 Cardiomyopathy Journal of Molecular Medicine (Berlin, Germany). Sep, 2008 | Pubmed ID: 18548221 Description of a Local Cardiac Adiponectin System and Its Deregulation in Dilated Cardiomyopathy European Heart Journal. May, 2008 | Pubmed ID: 18390538 Apoptosis Pathways and Oncolytic Adenoviral Vectors: Promising Targets and Tools to Overcome Therapy Resistance of Malignant Melanoma Experimental Dermatology. Jan, 2008 | Pubmed ID: 18095940 Dimethyl Sulfoxide Enhances Doxycycline-dependent Protein Expression in Tet-On Cells BioTechniques. Mar, 2007 | Pubmed ID: 17390537 A Bidirectional Tet-dependent Promotor Construct Regulating the Expression of E1A for Tight Control of Oncolytic Adenovirus Replication Journal of Biotechnology. Jan, 2007 | Pubmed ID: 17083991 Gene Therapy for Gastric Cancer: is It Promising? World Journal of Gastroenterology. Jan, 2006 | Pubmed ID: 16489636 An Improved Tet-On Regulatable FasL-adenovirus Vector System for Lung Cancer Therapy Journal of Molecular Medicine (Berlin, Germany). Mar, 2006 | Pubmed ID: 16437213 Viral and Nonviral Factors Causing Nonspecific Replication of Tumor- and Tissue-specific Promoter-dependent Oncolytic Adenoviruses Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2005 | Pubmed ID: 15771959 Selective Induction of Apoptosis in Melanoma Cells by Tyrosinase Promoter-controlled CD95 Ligand Overexpression The Journal of Investigative Dermatology. Jan, 2005 | Pubmed ID: 15654977 Regulation of Human Factor IX Expression Using Doxycycline-inducible Gene Expression System Thrombosis and Haemostasis. Sep, 2003 | Pubmed ID: 12958607 Molecular Genetic and Expression Analysis of Alpha-tocopherol Transfer Protein MRNA in German Shepherd Dogs with Degenerative Myelopathy Berliner Und Munchener Tierarztliche Wochenschrift. Jan-Feb, 2003 | Pubmed ID: 12592926 Induction of Coxsackievirus-adenovirus-receptor Expression During Myocardial Tissue Formation and Remodeling: Identification of a Cell-to-cell Contact-dependent Regulatory Mechanism Circulation. Feb, 2003 | Pubmed ID: 12591759 Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2 Thomas Hiller1, Viola Röhrs1, Eva-Maria Dehne2, Anke Wagner1,3, Henry Fechner1, Roland Lauster2, Jens Kurreck1 1Department of Applied Biochemistry, Institute of Biotechnology, Berlin University of Technology, 2Department of Medical Biotechnology, Institute of Biotechnology, Berlin University of Technology, 3Department of Bioprocess Engineering, Institute of Biotechnology, Berlin University of Technology JoVE 54633 Cancer Research
Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2 Thomas Hiller1, Viola Röhrs1, Eva-Maria Dehne2, Anke Wagner1,3, Henry Fechner1, Roland Lauster2, Jens Kurreck1 1Department of Applied Biochemistry, Institute of Biotechnology, Berlin University of Technology, 2Department of Medical Biotechnology, Institute of Biotechnology, Berlin University of Technology, 3Department of Bioprocess Engineering, Institute of Biotechnology, Berlin University of Technology JoVE 54633 Cancer Research