Jacqueline Naylor Cardiovascular & Metabolic Disease MedImmune Biography Publications Institution JoVE Articles Jacqueline Naylor has not added a biography. If you are Jacqueline Naylor and would like to personalize this page please email our Author Liaison for assistance. Publications Use of CRISPR/Cas9-engineered INS-1 Pancreatic β Cells to Define the Pharmacology of Dual GIPR/GLP-1R Agonists The Biochemical Journal. Sep, 2016 | Pubmed ID: 27422784 Natural and Synthetic Flavonoid Modulation of TRPC5 Channels British Journal of Pharmacology. Feb, 2016 | Pubmed ID: 26565375 Acoustic Dispensing Preserves the Potency of Therapeutic Peptides Throughout the Entire Drug Discovery Workflow Journal of Laboratory Automation. Feb, 2016 | Pubmed ID: 26002890 Use of the Site-specific Retargeting Jump-in Platform Cell Line to Support Biologic Drug Discovery Journal of Biomolecular Screening. Apr, 2015 | Pubmed ID: 25534831 Generation of Antibodies That Are Externally Acting Isoform-specific Inhibitors of Ion Channels Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23529435 Inhibition of Endothelial Cell Ca²⁺ Entry and Transient Receptor Potential Channels by Sigma-1 Receptor Ligands British Journal of Pharmacology. Mar, 2013 | Pubmed ID: 23121507 Pregnenolone Sulphate-independent Inhibition of TRPM3 Channels by Progesterone Cell Calcium. Jan, 2012 | Pubmed ID: 22000496 GVI Phospholipase A2 Role in the Stimulatory Effect of Sphingosine-1-phosphate on TRPC5 Cationic Channels Cell Calcium. Oct, 2011 | Pubmed ID: 21742378 Rapid and Contrasting Effects of Rosiglitazone on Transient Receptor Potential TRPM3 and TRPC5 Channels Molecular Pharmacology. Jun, 2011 | Pubmed ID: 21406603 TRPC5 Channel Sensitivities to Antioxidants and Hydroxylated Stilbenes The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21127073 TRPM3 Channel Stimulated by Pregnenolone Sulphate in Synovial Fibroblasts and Negatively Coupled to Hyaluronan BMC Musculoskeletal Disorders. Jun, 2010 | Pubmed ID: 20525329 Short-term Stimulation of Calcium-permeable Transient Receptor Potential Canonical 5-containing Channels by Oxidized Phospholipids Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2010 | Pubmed ID: 20378846 Pregnenolone Sulphate- and Cholesterol-regulated TRPM3 Channels Coupled to Vascular Smooth Muscle Secretion and Contraction Circulation Research. May, 2010 | Pubmed ID: 20360246 Robotic Multiwell Planar Patch-clamp for Native and Primary Mammalian Cells Nature Protocols. 2009 | Pubmed ID: 19197268 TRPC Channel Activation by Extracellular Thioredoxin Nature. Jan, 2008 | Pubmed ID: 18172497 A Sphingosine-1-phosphate-activated Calcium Channel Controlling Vascular Smooth Muscle Cell Motility Circulation Research. Jun, 2006 | Pubmed ID: 16675717 Sensing of Lysophospholipids by TRPC5 Calcium Channel The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16368680 Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays Jacqueline Naylor1, Alessandra Rossi1, Christopher Brankin2, David C. Hornigold1 1Cardiovascular & Metabolic Disease, MedImmune, 2Lab Automation and Support, MedImmune JoVE 54542 Biochemistry
Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays Jacqueline Naylor1, Alessandra Rossi1, Christopher Brankin2, David C. Hornigold1 1Cardiovascular & Metabolic Disease, MedImmune, 2Lab Automation and Support, MedImmune JoVE 54542 Biochemistry