Mario Roederer Vaccine Research Center, NIAID NIH Biography Publications Institution JoVE Articles Mario Roederer has not added a biography. If you are Mario Roederer and would like to personalize this page please email our Author Liaison for assistance. Publications Select Gp120 V2 Domain Specific Antibodies Derived from HIV and SIV Infection and Vaccination Inhibit Gp120 Binding to α4β7 PLoS Pathogens. Aug, 2018 | Pubmed ID: 30153309 HIV Vaccine Candidate Activation of Hypoxia and the Inflammasome in CD14 Monocytes is Associated with a Decreased Risk of SIV Acquisition Nature Medicine. Jun, 2018 | Pubmed ID: 29785023 A Genetic IFN/STAT1/FAS Axis Determines CD4 T Stem Cell Memory Levels and Apoptosis in Healthy Controls and Adult T-cell Leukemia Patients Oncoimmunology. 2018 | Pubmed ID: 29721391 The Early Expansion of Anergic NKG2A/CD56/CD16 Natural Killer Represents a Therapeutic Target in Haploidentical Hematopoietic Stem Cell Transplantation Haematologica. Aug, 2018 | Pubmed ID: 29700172 Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes Journal of Virology. 05, 2018 | Pubmed ID: 29444938 Toward Tuberculosis Vaccine Development: Recommendations for Nonhuman Primate Study Design Infection and Immunity. 02, 2018 | Pubmed ID: 29203540 Geographic Clonal Tracking in Macaques Provides Insights into HSPC Migration and Differentiation The Journal of Experimental Medicine. Jan, 2018 | Pubmed ID: 29141868 Trispecific Broadly Neutralizing HIV Antibodies Mediate Potent SHIV Protection in Macaques Science (New York, N.Y.). 10, 2017 | Pubmed ID: 28931639 Combined Single-cell Quantitation of Host and SIV Genes and Proteins Ex Vivo Reveals Host-pathogen Interactions in Individual Cells PLoS Pathogens. Jun, 2017 | Pubmed ID: 28654687 Attenuated PfSPZ Vaccine Induces Strain-transcending T Cells and Durable Protection Against Heterologous Controlled Human Malaria Infection Proceedings of the National Academy of Sciences of the United States of America. 03, 2017 | Pubmed ID: 28223498 Superiority in Rhesus Macaques of Targeting HIV-1 Env Gp140 to CD40 Versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses Journal of Virology. 05, 2017 | Pubmed ID: 28202751 Innate and Adaptive Immune Traits Are Differentially Affected by Genetic and Environmental Factors Nature Communications. Jan, 2017 | Pubmed ID: 28054551 Unique Cellular and Humoral Immunogenicity Profiles Generated by Aerosol, Intranasal, or Parenteral Vaccination in Rhesus Macaques Vaccine. 01, 2017 | Pubmed ID: 28041780 Highly Multiplexed, Single Cell Transcriptomic Analysis of T-Cells by Microfluidic PCR Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 27787802 Reconstitution of Peripheral T Cells by Tissue-Derived CCR4+ Central Memory Cells Following HIV-1 Antiretroviral Therapy Pathogens & Immunity. 2016 | Pubmed ID: 27819062 Rapid Development of a DNA Vaccine for Zika Virus Science (New York, N.Y.). 10, 2016 | Pubmed ID: 27708058 A Simple Tube Adapter to Expedite and Automate Thawing of Viably Frozen Cells Journal of Immunological Methods. 12, 2016 | Pubmed ID: 27594593 Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition Journal of Immunology (Baltimore, Md. : 1950). 10, 2016 | Pubmed ID: 27591322 Vaccine-Induced Antibodies That Neutralize Group 1 and Group 2 Influenza A Viruses Cell. Jul, 2016 | Pubmed ID: 27453470 Adjuvant-dependent Innate and Adaptive Immune Signatures of Risk of SIVmac251 Acquisition Nature Medicine. 07, 2016 | Pubmed ID: 27239761 Protection Against Malaria at 1 Year and Immune Correlates Following PfSPZ Vaccination Nature Medicine. 06, 2016 | Pubmed ID: 27158907 Targeting HIV-1 Env Gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques PloS One. 2016 | Pubmed ID: 27077384 Targeted Isolation of Antibodies Directed Against Major Sites of SIV Env Vulnerability PLoS Pathogens. Apr, 2016 | Pubmed ID: 27064278 FlowClean: Automated Identification and Removal of Fluorescence Anomalies in Flow Cytometry Data Cytometry. Part A : the Journal of the International Society for Analytical Cytology. 05, 2016 | Pubmed ID: 26990501 Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens Journal of Virology. Apr, 2016 | Pubmed ID: 26865719 Distributions of Autofluorescence After Compensation: Be Panglossian, Fret Not Cytometry. Part A : the Journal of the International Society for Analytical Cytology. 04, 2016 | Pubmed ID: 26859757 HISTORY OF SCIENCE. Flow Cytometry Strikes Gold Science (New York, N.Y.). Nov, 2015 | Pubmed ID: 26564833 Breakthrough Virus Neutralization Resistance As a Correlate of Protection in a Nonhuman Primate Heterologous Simian Immunodeficiency Virus Vaccine Challenge Study Journal of Virology. Dec, 2015 | Pubmed ID: 26423953 Parsimonious Determination of the Optimal Infectious Dose of a Pathogen for Nonhuman Primate Models PLoS Pathogens. Aug, 2015 | Pubmed ID: 26285041 OMIP-029: Human NK-cell Phenotypization Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2015 | Pubmed ID: 26228006 Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates Journal of Virology. Aug, 2015 | Pubmed ID: 26018159 A Proposal for Unified Flow Cytometer Parameter Naming Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Aug, 2015 | Pubmed ID: 25929439 The Genetic Architecture of the Human Immune System: a Bioresource for Autoimmunity and Disease Pathogenesis Cell. Apr, 2015 | Pubmed ID: 25772697 Filarial Infection Modulates the Immune Response to Mycobacterium Tuberculosis Through Expansion of CD4+ IL-4 Memory T Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2015 | Pubmed ID: 25667413 Antigen Expression Determines Adenoviral Vaccine Potency Independent of IFN and STING Signaling The Journal of Clinical Investigation. Mar, 2015 | Pubmed ID: 25642773 Safety and Immunogenicity of Ebola Virus and Marburg Virus Glycoprotein DNA Vaccines Assessed Separately and Concomitantly in Healthy Ugandan Adults: a Phase 1b, Randomised, Double-blind, Placebo-controlled Clinical Trial Lancet (London, England). Apr, 2015 | Pubmed ID: 25540891 Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-human Clinical Trial of Recombinant Human Interleukin-15 in Patients with Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2015 | Pubmed ID: 25403209 A Nonhuman Primate Toxicology and Immunogenicity Study Evaluating Aerosol Delivery of AERAS-402/Ad35 Vaccine: Evidence for Transient T Cell Responses in Peripheral Blood and Robust Sustained Responses in the Lungs Human Vaccines & Immunotherapeutics. 2014 | Pubmed ID: 25424923 Q and B Values Are Critical Measurements Required for Inter-instrument Standardization and Development of Multicolor Flow Cytometry Staining Panels Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2014 | Pubmed ID: 25346474 Homologous Boosting with Adenoviral Serotype 5 HIV Vaccine (rAd5) Vector Can Boost Antibody Responses Despite Preexisting Vector-specific Immunity in a Randomized Phase I Clinical Trial PloS One. 2014 | Pubmed ID: 25264782 Chimpanzee Adenovirus Vaccine Generates Acute and Durable Protective Immunity Against Ebolavirus Challenge Nature Medicine. Oct, 2014 | Pubmed ID: 25194571 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody in Vitro Improves Protection Against Lentiviral Infection in Vivo Journal of Virology. Nov, 2014 | Pubmed ID: 25142607 Aerosol Vaccination with AERAS-402 Elicits Robust Cellular Immune Responses in the Lungs of Rhesus Macaques but Fails to Protect Against High-dose Mycobacterium Tuberculosis Challenge Journal of Immunology (Baltimore, Md. : 1950). Aug, 2014 | Pubmed ID: 25024382 Establishment and Maintenance of a PBMC Repository for Functional Cellular Studies in Support of Clinical Vaccine Trials Journal of Immunological Methods. Jul, 2014 | Pubmed ID: 24787274 Phase I Randomized Clinical Trial of VRC DNA and RAd5 HIV-1 Vaccine Delivery by Intramuscular (i.m.), Subcutaneous (s.c.) and Intradermal (i.d.) Administration (VRC 011) PloS One. 2014 | Pubmed ID: 24621858 Loss of Circulating CD4 T Cells with B Cell Helper Function During Chronic HIV Infection PLoS Pathogens. Jan, 2014 | Pubmed ID: 24497824 Immunological and Virological Mechanisms of Vaccine-mediated Protection Against SIV and HIV Nature. Jan, 2014 | Pubmed ID: 24352234 Differential Impact of Magnitude, Polyfunctional Capacity, and Specificity of HIV-specific CD8+ T Cell Responses on HIV Set Point Journal of Virology. Feb, 2014 | Pubmed ID: 24227857 Mixture Models for Single-cell Assays with Applications to Vaccine Studies Biostatistics (Oxford, England). Jan, 2014 | Pubmed ID: 23887981 Safety and Tolerability of a Live Oral Salmonella Typhimurium Vaccine Candidate in SIV-infected Nonhuman Primates Vaccine. Dec, 2013 | Pubmed ID: 24099872 Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine Science (New York, N.Y.). Sep, 2013 | Pubmed ID: 23929949 OMIP-019: Quantification of Human γδT-cells, INKT-cells, and Hematopoietic Precursors Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Aug, 2013 | Pubmed ID: 23897714 DNA Vaccine Delivered by a Needle-free Injection Device Improves Potency of Priming for Antibody and CD8+ T-cell Responses After RAd5 Boost in a Randomized Clinical Trial PloS One. 2013 | Pubmed ID: 23577062 Highly Multiplexed Quantitation of Gene Expression on Single Cells Journal of Immunological Methods. May, 2013 | Pubmed ID: 23500781 Therapeutic Vaccination Expands and Improves the Function of the HIV-specific Memory T-cell Repertoire The Journal of Infectious Diseases. Jun, 2013 | Pubmed ID: 23482645 OMIP-017: Human CD4(+) Helper T-cell Subsets Including Follicular Helper Cells Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2013 | Pubmed ID: 23450796 Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-specific CD8+ T Cells Following Human-, Simian-, and Chimpanzee-derived Recombinant Adenoviral Vector Immunization Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23390298 Quantifying Spillover Spreading for Comparing Instrument Performance and Aiding in Multicolor Panel Design Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Mar, 2013 | Pubmed ID: 23389989 Superior T Memory Stem Cell Persistence Supports Long-lived T Cell Memory The Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23281401 Data Exploration, Quality Control and Testing in Single-cell QPCR-based Gene Expression Experiments Bioinformatics (Oxford, England). Feb, 2013 | Pubmed ID: 23267174 Identification, Isolation and in Vitro Expansion of Human and Nonhuman Primate T Stem Cell Memory Cells Nature Protocols. Jan, 2013 | Pubmed ID: 23222456 Early Immunologic and Virologic Predictors of Clinical HIV-1 Disease Progression AIDS (London, England). Mar, 2013 | Pubmed ID: 23211771 OMIP-015: Human Regulatory and Activated T-cells Without Intracellular Staining Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Feb, 2013 | Pubmed ID: 23166007 Quality Assurance for Polychromatic Flow Cytometry Using a Suite of Calibration Beads Nature Protocols. Dec, 2012 | Pubmed ID: 23138348 OMIP-013: Differentiation of Human T-cells Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2012 | Pubmed ID: 23027685 Increased Memory Differentiation is Associated with Decreased Polyfunctionality for HIV but Not for Cytomegalovirus-specific CD8+ T Cells Journal of Immunology (Baltimore, Md. : 1950). Oct, 2012 | Pubmed ID: 22966086 Optimization and Qualification of an 8-color Intracellular Cytokine Staining Assay for Quantifying T Cell Responses in Rhesus Macaques for Pre-clinical Vaccine Studies Journal of Immunological Methods. Dec, 2012 | Pubmed ID: 22955212 CD4 T Follicular Helper Cell Dynamics During SIV Infection The Journal of Clinical Investigation. Sep, 2012 | Pubmed ID: 22922258 HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins Journal of Virology. Oct, 2012 | Pubmed ID: 22875963 Priming T-cell Responses with Recombinant Measles Vaccine Vector in a Heterologous Prime-boost Setting in Non-human Primates Vaccine. Sep, 2012 | Pubmed ID: 22732429 Brilliant Violet Fluorophores: a New Class of Ultrabright Fluorescent Compounds for Immunofluorescence Experiments Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jun, 2012 | Pubmed ID: 22489009 A Deep Profiler's Guide to Cytometry Trends in Immunology. Jul, 2012 | Pubmed ID: 22476049 OMIP-009: Characterization of Antigen-specific Human T-cells Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2012 | Pubmed ID: 22438322 OMIP-005: Quality and Phenotype of Antigen-responsive Rhesus Macaque T Cells Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2012 | Pubmed ID: 22438313 Virus Inhibition Activity of Effector Memory CD8(+) T Cells Determines Simian Immunodeficiency Virus Load in Vaccinated Monkeys After Vaccine Breakthrough Infection Journal of Virology. May, 2012 | Pubmed ID: 22419810 Cytometry: Today's Technology and Tomorrow's Horizons Methods (San Diego, Calif.). Jul, 2012 | Pubmed ID: 22391486 The Simian Immunodeficiency Virus Targets Central Cell Cycle Functions Through Transcriptional Repression in Vivo PloS One. 2011 | Pubmed ID: 22043290 A Human Memory T Cell Subset with Stem Cell-like Properties Nature Medicine. Sep, 2011 | Pubmed ID: 21926977 CD8+ Cellular Immunity Mediates RAd5 Vaccine Protection Against Ebola Virus Infection of Nonhuman Primates Nature Medicine. Sep, 2011 | Pubmed ID: 21857654 Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing Science (New York, N.Y.). Sep, 2011 | Pubmed ID: 21835983 High-throughput Quantitative Analysis of HIV-1 and SIV-specific ADCC-mediating Antibody Responses Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Aug, 2011 | Pubmed ID: 21735545 Single-cell Gene-expression Profiling Reveals Qualitatively Distinct CD8 T Cells Elicited by Different Gene-based Vaccines Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21422297 Safety (toxicity), Pharmacokinetics, Immunogenicity, and Impact on Elements of the Normal Immune System of Recombinant Human IL-15 in Rhesus Macaques Blood. May, 2011 | Pubmed ID: 21385847 Recombinant Adenovirus Serotype 26 (Ad26) and Ad35 Vaccine Vectors Bypass Immunity to Ad5 and Protect Nonhuman Primates Against Ebolavirus Challenge Journal of Virology. May, 2011 | Pubmed ID: 21325402 SPICE: Exploration and Analysis of Post-cytometric Complex Multivariate Datasets Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Feb, 2011 | Pubmed ID: 21265010 Rapid SIV Env-specific Mucosal and Serum Antibody Induction Augments Cellular Immunity in Protecting Immunized, Elite-controller Macaques Against High Dose Heterologous SIV Challenge Virology. Mar, 2011 | Pubmed ID: 21237474 Heavy Metal Contaminants Can Eliminate Quantum Dot Fluorescence Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jan, 2011 | Pubmed ID: 21182185 Genetic Immunization in the Lung Induces Potent Local and Systemic Immune Responses Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21135247 OMIP-002: Phenotypic Analysis of Specific Human CD8+ T-cells Using Peptide-MHC Class I Multimers for Any of Four Epitopes Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2010 | Pubmed ID: 20722006 OMIP-001: Quality and Phenotype of Ag-responsive Human T-cells Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2010 | Pubmed ID: 20722005 Publication of Optimized Multicolor Immunofluorescence Panels Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2010 | Pubmed ID: 20722004 Vector Choice Determines Immunogenicity and Potency of Genetic Vaccines Against Angola Marburg Virus in Nonhuman Primates Journal of Virology. Oct, 2010 | Pubmed ID: 20660192 Transient and Persistent Effects of IL-15 on Lymphocyte Homeostasis in Nonhuman Primates Blood. Oct, 2010 | Pubmed ID: 20631381 Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 Science (New York, N.Y.). Aug, 2010 | Pubmed ID: 20616233 Good Cell, Bad Cell: Flow Cytometry Reveals T-cell Subsets Important in HIV Disease Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jul, 2010 | Pubmed ID: 20583275 Data Analysis in Flow Cytometry: the Future Just Started Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jul, 2010 | Pubmed ID: 20583274 Amine-reactive Dyes for Dead Cell Discrimination in Fixed Samples Current Protocols in Cytometry. Jul, 2010 | Pubmed ID: 20578108 IL-10 Production Differentially Influences the Magnitude, Quality, and Protective Capacity of Th1 Responses Depending on the Vaccine Platform The Journal of Experimental Medicine. Jul, 2010 | Pubmed ID: 20530206 Demonstration of Cross-protective Vaccine Immunity Against an Emerging Pathogenic Ebolavirus Species PLoS Pathogens. May, 2010 | Pubmed ID: 20502688 Phenotypic and Functional Profile of HIV-inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/boost Vaccination Journal of Virology. May, 2010 | Pubmed ID: 20200250 Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-cell Responses PloS One. Feb, 2010 | Pubmed ID: 20126394 The Use of Quantum Dot Nanocrystals in Multicolor Flow Cytometry Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Jul-Aug, 2010 | Pubmed ID: 20101649 Immunologic and Virologic Events in Early HIV Infection Predict Subsequent Rate of Progression The Journal of Infectious Diseases. Jan, 2010 | Pubmed ID: 20001854 Distribution, Persistence, and Efficacy of Adoptively Transferred Central and Effector Memory-derived Autologous Simian Immunodeficiency Virus-specific CD8+ T Cell Clones in Rhesus Macaques During Acute Infection Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 19949091 Trafficking, Persistence, and Activation State of Adoptively Transferred Allogeneic and Autologous Simian Immunodeficiency Virus-specific CD8(+) T Cell Clones During Acute and Chronic Infection of Rhesus Macaques Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 19949089 Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization Journal of Virology. Jan, 2010 | Pubmed ID: 19846512 Autocrine Production of Beta-chemokines Protects CMV-Specific CD4 T Cells from HIV Infection PLoS Pathogens. Oct, 2009 | Pubmed ID: 19876388 CD4 T Cell Subsets in the Mucosa Are CD28+Ki-67-HLA-DR-CD69+ but Show Differential Infection Based on Alpha4beta7 Receptor Expression During Acute SIV Infection Journal of Medical Primatology. Oct, 2009 | Pubmed ID: 19863675 Alpha4(+)beta7(hi)CD4(+) Memory T Cells Harbor Most Th-17 Cells and Are Preferentially Infected During Acute SIV Infection Mucosal Immunology. Sep, 2009 | Pubmed ID: 19571800 Differential Association of Programmed Death-1 and CD57 with Ex Vivo Survival of CD8+ T Cells in HIV Infection Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19564339 Flow Cytometry and the Future of Vaccine Development Expert Review of Vaccines. Jun, 2009 | Pubmed ID: 19485757 High Frequencies of Resting CD4+ T Cells Containing Integrated Viral DNA Are Found in Rhesus Macaques During Acute Lentivirus Infections Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19416840 Public Clonotype Usage Identifies Protective Gag-specific CD8+ T Cell Responses in SIV Infection The Journal of Experimental Medicine. Apr, 2009 | Pubmed ID: 19349463 Replication-defective Adenovirus Vectors with Multiple Deletions Do Not Induce Measurable Vector-specific T Cells in Human Trials Journal of Virology. Jun, 2009 | Pubmed ID: 19339347 Increased IL-15 Production is Associated with Higher Susceptibility of Memory CD4 T Cells to Simian Immunodeficiency Virus During Acute Infection Journal of Immunology (Baltimore, Md. : 1950). Feb, 2009 | Pubmed ID: 19155491 High Avidity Myeloid Leukemia-associated Antigen-specific CD8+ T Cells Preferentially Reside in the Bone Marrow Blood. Mar, 2009 | Pubmed ID: 18997173 Emerging Concepts in the Immunopathogenesis of AIDS Annual Review of Medicine. 2009 | Pubmed ID: 18947296 A Chromatic Explosion: the Development and Future of Multiparameter Flow Cytometry Immunology. Dec, 2008 | Pubmed ID: 19137647 Techniques to Improve the Direct Ex Vivo Detection of Low Frequency Antigen-specific CD8+ T Cells with Peptide-major Histocompatibility Complex Class I Tetramers Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2008 | Pubmed ID: 18836993 A SARS DNA Vaccine Induces Neutralizing Antibody and Cellular Immune Responses in Healthy Adults in a Phase I Clinical Trial Vaccine. Nov, 2008 | Pubmed ID: 18824060 Gating-ML: XML-based Gating Descriptions in Flow Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2008 | Pubmed ID: 18773465 Antiretroviral Therapy Prior to Acute Viral Replication Preserves CD4 T Cells in the Periphery but Not in Rectal Mucosa During Acute Simian Immunodeficiency Virus Infection Journal of Virology. Nov, 2008 | Pubmed ID: 18768962 Polychromatic Plots: Graphical Display of Multidimensional Data Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2008 | Pubmed ID: 18629844 IL-15 Expands Unconventional CD8alphaalphaNK1.1+ T Cells but Not Valpha14Jalpha18+ NKT Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18490727 T-cell Quality in Memory and Protection: Implications for Vaccine Design Nature Reviews. Immunology. Apr, 2008 | Pubmed ID: 18323851 How Many Events is Enough? Are You Positive? Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2008 | Pubmed ID: 18307257 Polyfunctional T Cell Responses Are a Hallmark of HIV-2 Infection European Journal of Immunology. Feb, 2008 | Pubmed ID: 18200635 A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults During a Phase 1 Clinical Trial The Journal of Infectious Diseases. Dec, 2007 | Pubmed ID: 18190252 Optimizing a Multicolor Immunophenotyping Assay Clinics in Laboratory Medicine. Sep, 2007 | Pubmed ID: 17658403 Multifunctional TH1 Cells Define a Correlate of Vaccine-mediated Protection Against Leishmania Major Nature Medicine. Jul, 2007 | Pubmed ID: 17558415 Immunization with Vaccinia Virus Induces Polyfunctional and Phenotypically Distinctive CD8(+) T Cell Responses The Journal of Experimental Medicine. Jun, 2007 | Pubmed ID: 17535971 Estimating the Infectivity of CCR5-tropic Simian Immunodeficiency Virus SIV(mac251) in the Gut Journal of Virology. Aug, 2007 | Pubmed ID: 17507462 SIV-specific CD8+ T Cells Express High Levels of PD1 and Cytokines but Have Impaired Proliferative Capacity in Acute and Chronic SIVmac251 Infection Blood. Aug, 2007 | Pubmed ID: 17440051 Safety and Immunogenicity of a Gag-Pol Candidate HIV-1 DNA Vaccine Administered by a Needle-free Device in HIV-1-seronegative Subjects Journal of Acquired Immune Deficiency Syndromes (1999). Apr, 2007 | Pubmed ID: 17325604 Increased Immunofluorescence Sensitivity Using 532 Nm Laser Excitation Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Feb, 2007 | Pubmed ID: 17200955 Differential Susceptibility of Leukocyte Subsets to Cytotoxic T Cell Killing: Implications for HIV Immunopathogenesis Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Feb, 2007 | Pubmed ID: 17200952 Safety, Immunogenicity and Efficacy of Modified Vaccinia Ankara (MVA) Against Dryvax Challenge in Vaccinia-naïve and Vaccinia-immune Individuals Vaccine. Feb, 2007 | Pubmed ID: 17126963 HIV Vaccines: Can Mucosal CD4 T Cells Be Protected? Current Opinion in HIV and AIDS. Jul, 2006 | Pubmed ID: 19372821 Acute HIV Infection: It Takes More Than Guts Current Opinion in HIV and AIDS. Jan, 2006 | Pubmed ID: 19372777 Quality Assurance for Polychromatic Flow Cytometry Nature Protocols. 2006 | Pubmed ID: 17406444 Intracellular Cytokine Optimization and Standard Operating Procedure Nature Protocols. 2006 | Pubmed ID: 17406442 Live-cell Assay to Detect Antigen-specific CD4+ T-cell Responses by CD154 Expression Nature Protocols. 2006 | Pubmed ID: 17406204 Acquisition of Direct Antiviral Effector Functions by CMV-specific CD4+ T Lymphocytes with Cellular Maturation The Journal of Experimental Medicine. Dec, 2006 | Pubmed ID: 17158960 Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV-1 DNA Candidate Vaccine The Journal of Infectious Diseases. Dec, 2006 | Pubmed ID: 17109336 Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV-1 Candidate Vaccine Delivered by a Replication-defective Recombinant Adenovirus Vector The Journal of Infectious Diseases. Dec, 2006 | Pubmed ID: 17109335 Systemic Vaccination Prevents the Total Destruction of Mucosal CD4 T Cells During Acute SIV Challenge Journal of Medical Primatology. Aug, 2006 | Pubmed ID: 16872285 Amine Reactive Dyes: an Effective Tool to Discriminate Live and Dead Cells in Polychromatic Flow Cytometry Journal of Immunological Methods. Jun, 2006 | Pubmed ID: 16756987 Vaccination Preserves CD4 Memory T Cells During Acute Simian Immunodeficiency Virus Challenge The Journal of Experimental Medicine. Jun, 2006 | Pubmed ID: 16735692 Immune Protection of Nonhuman Primates Against Ebola Virus with Single Low-dose Adenovirus Vectors Encoding Modified GPs PLoS Medicine. Jun, 2006 | Pubmed ID: 16683867 Toll-like Receptor Agonists Influence the Magnitude and Quality of Memory T Cell Responses After Prime-boost Immunization in Nonhuman Primates The Journal of Experimental Medicine. May, 2006 | Pubmed ID: 16636134 HIV Nonprogressors Preferentially Maintain Highly Functional HIV-specific CD8+ T Cells Blood. Jun, 2006 | Pubmed ID: 16467198 Infectious Molecular Clones from a Simian Immunodeficiency Virus-infected Rapid-progressor (RP) Macaque: Evidence of Differential Selection of RP-specific Envelope Mutations in Vitro and in Vivo Journal of Virology. Feb, 2006 | Pubmed ID: 16415023 Massive Infection and Loss of Memory CD4+ T Cells in Multiple Tissues During Acute SIV Infection Nature. Apr, 2005 | Pubmed ID: 15793563 Vaccination in Humans Generates Broad T Cell Cytokine Responses Journal of Immunology (Baltimore, Md. : 1950). Nov, 2004 | Pubmed ID: 15494483 Seventeen-colour Flow Cytometry: Unravelling the Immune System Nature Reviews. Immunology. 08, 2004 | Pubmed ID: 15286731 The Functional Profile of Primary Human Antiviral CD8+ T Cell Effector Activity is Dictated by Cognate Peptide Concentration Journal of Immunology (Baltimore, Md. : 1950). May, 2004 | Pubmed ID: 15128832 T-cell Dynamics During Acute SIV Infection AIDS (London, England). Jan, 2004 | Pubmed ID: 15090825 Flow Cytometric Analysis of Vaccine Responses: How Many Colors Are Enough? Clinical Immunology (Orlando, Fla.). Mar, 2004 | Pubmed ID: 15047198 Sensitive and Viable Identification of Antigen-specific CD8+ T Cells by a Flow Cytometric Assay for Degranulation Journal of Immunological Methods. Oct, 2003 | Pubmed ID: 14580882 Toll-like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-specific T Cell Responses Journal of Immunology (Baltimore, Md. : 1950). Oct, 2003 | Pubmed ID: 14530357 Measuring Containment of Viable Infectious Cell Sorting in High-velocity Cell Sorters Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Apr, 2003 | Pubmed ID: 12655656 Optimized Determination of T Cell Epitope Responses Journal of Immunological Methods. Mar, 2003 | Pubmed ID: 12609547 Compensation in Flow Cytometry Current Protocols in Cytometry. Dec, 2002 | Pubmed ID: 18770762 Multiparameter FACS Analysis Current Protocols in Immunology. Aug, 2002 | Pubmed ID: 18432886 Human Immunodeficiency Virus Type 1 Neutralization Measured by Flow Cytometric Quantitation of Single-round Infection of Primary Human T Cells Journal of Virology. May, 2002 | Pubmed ID: 11967298 Single-cell Quantitation of mRNA and Surface Protein Expression in Simian Immunodeficiency Virus-infected CD4+ T Cells Isolated from Rhesus macaques Andrey Tokarev1, Matthew Creegan1, Michael A. Eller1, Mario Roederer2, Diane L. Bolton1 1US Military HIV Research Program, Henry M. Jackson Foundation, Walter Reed Army Institute of Research, 2Vaccine Research Center, NIAID, NIH JoVE 57776 Immunology and Infection
Single-cell Quantitation of mRNA and Surface Protein Expression in Simian Immunodeficiency Virus-infected CD4+ T Cells Isolated from Rhesus macaques Andrey Tokarev1, Matthew Creegan1, Michael A. Eller1, Mario Roederer2, Diane L. Bolton1 1US Military HIV Research Program, Henry M. Jackson Foundation, Walter Reed Army Institute of Research, 2Vaccine Research Center, NIAID, NIH JoVE 57776 Immunology and Infection