Wang Wang Mitochondria and Metabolism Center, Department of Anesthesiology and Pain Medicine University of Washington Biography Publications Institution JoVE Articles Wang Wang has not added a biography. If you are Wang Wang and would like to personalize this page please email our Author Liaison for assistance. Publications [Prognostic Factors and Outcomes of Legg-Calvé-Perthes Disease] Zhonghua Yi Xue Za Zhi. Jun, 2013 | Pubmed ID: 24125673 [Study on Human AFGF Fusion Gene Transformation with Soybean 24 KDa Oleosin and Expression in Safflower] Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. Jun, 2013 | Pubmed ID: 24066580 Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure Cell Metabolism. Aug, 2013 | Pubmed ID: 23931755 Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia-reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues Journal of the American Heart Association. Aug, 2013 | Pubmed ID: 23817469 Loss of P47phox Subunit Enhances Susceptibility to Biomechanical Stress and Heart Failure Because of Dysregulation of Cortactin and Actin Filaments Circulation Research. Jun, 2013 | Pubmed ID: 23553616 Respective Contribution of Mitochondrial Superoxide and PH to Mitochondria-targeted Circularly Permuted Yellow Fluorescent Protein (mt-cpYFP) Flash Activity The Journal of Biological Chemistry. Apr, 2013 | Pubmed ID: 23457298 Noncanonical EF-hand Motif Strategically Delays Ca(2+) Buffering to Enhance Cardiac Performance Nature Medicine. Feb, 2013 | Pubmed ID: 23396207 Wnt5a Inhibits Hypoxia-induced Pulmonary Arterial Smooth Muscle Cell Proliferation by Downregulation of β-catenin American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2013 | Pubmed ID: 23144322 Enhanced Recovery from Ischemia-reperfusion Injury in PI3Kα Dominant Negative Hearts: Investigating the Role of Alternate PI3K Isoforms, Increased Glucose Oxidation and MAPK Signaling Journal of Molecular and Cellular Cardiology. Jan, 2013 | Pubmed ID: 23142539 Calcium Mishandling in Diastolic Dysfunction: Mechanisms and Potential Therapies Biochimica Et Biophysica Acta. Apr, 2013 | Pubmed ID: 23022395 N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides As Selective Inhibitors of Mutant H1047R Phosphoinositide-3-kinase (PI3Kα) Bioorganic & Medicinal Chemistry. Dec, 2012 | Pubmed ID: 23121722 Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges Cardiology Research and Practice. 2012 | Pubmed ID: 22655211 Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-converting Enzyme 2-null Mice Hypertension. Jun, 2012 | Pubmed ID: 22508831 Loss of Angiotensin-converting Enzyme-2 Exacerbates Diabetic Cardiovascular Complications and Leads to Systolic and Vascular Dysfunction: a Critical Role of the Angiotensin II/AT1 Receptor Axis Circulation Research. May, 2012 | Pubmed ID: 22474255 Superoxide Flashes Reveal Novel Properties of Mitochondrial Reactive Oxygen Species Excitability in Cardiomyocytes Biophysical Journal. Mar, 2012 | Pubmed ID: 22404923 Role of ACE2 in Diastolic and Systolic Heart Failure Heart Failure Reviews. Sep, 2012 | Pubmed ID: 21638102 Response to "A Critical Evaluation of CpYFP As a Probe for Superoxide" Free Radical Biology & Medicine. Nov, 2011 | Pubmed ID: 21925593 Imaging Superoxide Flash and Metabolism-coupled Mitochondrial Permeability Transition in Living Animals Cell Research. Sep, 2011 | Pubmed ID: 21556035 Use of Ginseng to Reduce Post-myocardial Adverse Myocardial Remodeling: Applying Scientific Principles to the Use of Herbal Therapies Journal of Molecular Medicine (Berlin, Germany). Apr, 2011 | Pubmed ID: 21340500 Enhanced Susceptibility to Biomechanical Stress in ACE2 Null Mice is Prevented by Loss of the P47(phox) NADPH Oxidase Subunit Cardiovascular Research. Jul, 2011 | Pubmed ID: 21285291 Prevention of Angiotensin II-mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-converting Enzyme 2 Hypertension. Feb, 2011 | Pubmed ID: 21189404 Different Strategies for Preparation of Non-tagged RV270 Protein and Its Efficacy Against Yersinia Pestis Challenge Biomedical and Environmental Sciences : BES. Oct, 2010 | Pubmed ID: 21112480 [Evaluation of Immunization Protection Efficacy of Plague Subunit Vaccine] Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine]. Sep, 2009 | Pubmed ID: 20137561 Parvalbumin: Targeting Calcium Handling in Cardiac Diastolic Dysfunction General Physiology and Biophysics. 2009 | Pubmed ID: 20093724 Involvement of the Post-transcriptional Regulator Hfq in Yersinia Pestis Virulence PloS One. 2009 | Pubmed ID: 19593436 Artificial Selection for Whole Animal Low Intrinsic Aerobic Capacity Co-segregates with Hypoxia-induced Cardiac Pump Failure PloS One. 2009 | Pubmed ID: 19568432 Molecular Cardiology in Translation: Gene, Cell and Chemical-based Experimental Therapeutics for the Failing Heart Journal of Cardiovascular Translational Research. Dec, 2008 | Pubmed ID: 19956787 Superoxide Flashes: Illuminating New Insights into Cardiac Ischemia/reperfusion Injury Future Cardiology. Nov, 2008 | Pubmed ID: 19649173 Designing Heart Performance by Gene Transfer Physiological Reviews. Oct, 2008 | Pubmed ID: 18923190 Superoxide Flashes in Single Mitochondria Cell. Jul, 2008 | Pubmed ID: 18662543 Parvalbumin Isoforms for Enhancing Cardiac Diastolic Function Cell Biochemistry and Biophysics. 2008 | Pubmed ID: 18458829 Transforming Growth Factor Beta Induces Apoptosis Through Repressing the Phosphoinositide 3-kinase/AKT/survivin Pathway in Colon Cancer Cells Cancer Research. May, 2008 | Pubmed ID: 18451140 Cardiac-directed Parvalbumin Transgene Expression in Mice Shows Marked Heart Rate Dependence of Delayed Ca2+ Buffering Action Physiological Genomics. May, 2008 | Pubmed ID: 18334547 Novel Anti-oxidative Role of Calreticulin in Protecting A549 Human Type II Alveolar Epithelial Cells Against Hypoxic Injury American Journal of Physiology. Cell Physiology. Jan, 2008 | Pubmed ID: 17959730 Ellagic Acid from Acorn Fringe by Enzymatic Hydrolysis and Combined Effects of Operational Variables and Enzymes on Yield of the Production Bioresource Technology. Apr, 2008 | Pubmed ID: 17544268 Parvalbumin Isoforms Differentially Accelerate Cardiac Myocyte Relaxation Kinetics in an Animal Model of Diastolic Dysfunction American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2007 | Pubmed ID: 17545482 Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca2+ Cycling Circulation Research. Jan, 2007 | Pubmed ID: 17138943 Endogenous Calcitonin Gene-related Peptide Protects Human Alveolar Epithelial Cells Through Protein Kinase Cepsilon and Heat Shock Protein The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15784626 ASF/SF2-regulated CaMKIIdelta Alternative Splicing Temporally Reprograms Excitation-contraction Coupling in Cardiac Muscle Cell. Jan, 2005 | Pubmed ID: 15652482 Phosphatidylinositol 3-kinase Offsets CAMP-mediated Positive Inotropic Effect Via Inhibiting Ca2+ Influx in Cardiomyocytes Circulation Research. Dec, 2004 | Pubmed ID: 15539636 Sustained Beta1-adrenergic Stimulation Modulates Cardiac Contractility by Ca2+/calmodulin Kinase Signaling Pathway Circulation Research. Oct, 2004 | Pubmed ID: 15375008 Intramuscular Gene Transfer of CGRP Inhibits Neointimal Hyperplasia After Balloon Injury in the Rat Abdominal Aorta American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2004 | Pubmed ID: 15371265 Imaging Microdomain Ca2+ in Muscle Cells Circulation Research. Apr, 2004 | Pubmed ID: 15117829 Alteration of Vascular Response to Norepinephrine, Calcitonin Gene-related Peptide, and Acetylcholine in Orchidectomized Rats Acta Pharmacologica Sinica. Nov, 2002 | Pubmed ID: 12889471 Confocal Imaging of Single Mitochondrial Superoxide Flashes in Intact Heart or In Vivo Guohua Gong1, Wang Wang1 1Mitochondria and Metabolism Center, Department of Anesthesiology and Pain Medicine, University of Washington JoVE 50818 Biology
Confocal Imaging of Single Mitochondrial Superoxide Flashes in Intact Heart or In Vivo Guohua Gong1, Wang Wang1 1Mitochondria and Metabolism Center, Department of Anesthesiology and Pain Medicine, University of Washington JoVE 50818 Biology