Xin-zhuan Su National Institute of Allergy and Infectious Diseases National Institutes of Health Biography Publications Institution JoVE Articles Xin-zhuan Su has not added a biography. If you are Xin-zhuan Su and would like to personalize this page please email our Author Liaison for assistance. Publications Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria ACS Medicinal Chemistry Letters. Feb, 2012 | Pubmed ID: 22328964 Directional Gene Expression and Antisense Transcripts in Sexual and Asexual Stages of Plasmodium Falciparum BMC Genomics. 2011 | Pubmed ID: 22129310 Macrophage Migration Inhibitory Factor Homolog from Plasmodium Yoelii Modulates Monocyte Recruitment and Activation in Spleen During Infection Parasitology Research. Oct, 2011 | Pubmed ID: 22015474 A New Malaria Antigen Produces Partial Protection Against Plasmodium Yoelii Challenge Parasitology Research. Sep, 2011 | Pubmed ID: 21915626 Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets Science (New York, N.Y.). Aug, 2011 | Pubmed ID: 21817045 Linkage Maps from Multiple Genetic Crosses and Loci Linked to Growth-related Virulent Phenotype in Plasmodium Yoelii Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21690382 Population Genetic Analysis of Plasmodium Falciparum Parasites Using a Customized Illumina GoldenGate Genotyping Assay PloS One. 2011 | Pubmed ID: 21673999 Challenges and Prospects for Malaria Elimination in the Greater Mekong Subregion Acta Tropica. Apr, 2011 | Pubmed ID: 21515238 Discovery of New Antimalarial Chemotypes Through Chemical Methodology and Library Development Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21498685 High Recombination Rates and Hotspots in a Plasmodium Falciparum Genetic Cross Genome Biology. 2011 | Pubmed ID: 21463505 Malaria in the Greater Mekong Subregion: Heterogeneity and Complexity Acta Tropica. Mar, 2011 | Pubmed ID: 21382335 Effect of PCR Extension Temperature on High-throughput Sequencing Molecular and Biochemical Parasitology. Mar, 2011 | Pubmed ID: 21112355 Recent Progress in Functional Genomic Research in Plasmodium Falciparum Current Genomics. Jun, 2010 | Pubmed ID: 21119892 Lack of Allele-specific Efficacy of a Bivalent AMA1 Malaria Vaccine Malaria Journal. 2010 | Pubmed ID: 20565971 Use of Magnetically Purified Plasmodium Falciparum Parasites Improves the Accuracy of Erythrocyte Invasion Assays Experimental Parasitology. Oct, 2010 | Pubmed ID: 20493844 Human Malaria Parasites: Are We Ready for a New Species? The Journal of Infectious Diseases. May, 2010 | Pubmed ID: 20380563 Increased Tolerance to Artemisinin in Plasmodium Falciparum is Mediated by a Quiescence Mechanism Antimicrobial Agents and Chemotherapy. May, 2010 | Pubmed ID: 20160056 Plasmodium Falciparum Genome-wide Scans for Positive Selection, Recombination Hot Spots and Resistance to Antimalarial Drugs Nature Genetics. Mar, 2010 | Pubmed ID: 20101240 Discovery, Mechanisms of Action and Combination Therapy of Artemisinin Expert Review of Anti-infective Therapy. Oct, 2009 | Pubmed ID: 19803708 Genetic Mapping of Targets Mediating Differential Chemical Phenotypes in Plasmodium Falciparum Nature Chemical Biology. Oct, 2009 | Pubmed ID: 19734910 Large-scale Genotyping and Genetic Mapping in Plasmodium Parasites The Korean Journal of Parasitology. Jun, 2009 | Pubmed ID: 19488413 Hundreds of Microsatellites for Genotyping Plasmodium Yoelii Parasites Molecular and Biochemical Parasitology. Aug, 2009 | Pubmed ID: 19450732 Disruption of a Plasmodium Falciparum Multidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione The Journal of Biological Chemistry. Mar, 2009 | Pubmed ID: 19117944 Drug Resistance and Genetic Mapping in Plasmodium Falciparum Current Genetics. Nov, 2008 | Pubmed ID: 18802698 Detection of Genome-wide Polymorphisms in the AT-rich Plasmodium Falciparum Genome Using a High-density Microarray BMC Genomics. 2008 | Pubmed ID: 18724869 Effects of Plasmodium Falciparum Mixed Infections on in Vitro Antimalarial Drug Tests and Genotyping The American Journal of Tropical Medicine and Hygiene. Aug, 2008 | Pubmed ID: 18689621 Genome-wide Compensatory Changes Accompany Drug- Selected Mutations in the Plasmodium Falciparum Crt Gene PloS One. 2008 | Pubmed ID: 18575593 Population Structure of the Genes Encoding the Polymorphic Plasmodium Falciparum Apical Membrane Antigen 1: Implications for Vaccine Design Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008 | Pubmed ID: 18515425 Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression During in Vitro Plasmodium Falciparum Development Eukaryotic Cell. Jul, 2008 | Pubmed ID: 18487348 Changes in the Plasmodial Surface Anion Channel Reduce Leupeptin Uptake and Can Confer Drug Resistance in Plasmodium Falciparum-infected Erythrocytes Antimicrobial Agents and Chemotherapy. Jul, 2008 | Pubmed ID: 18443109 Local Adaptation and Vector-mediated Population Structure in Plasmodium Vivax Malaria Molecular Biology and Evolution. Jun, 2008 | Pubmed ID: 18385220 Diversity and Evolution of the Rhoph1/clag Multigene Family of Plasmodium Falciparum Molecular and Biochemical Parasitology. Mar, 2008 | Pubmed ID: 18155305 Structural Polymorphism and Diversifying Selection on the Pregnancy Malaria Vaccine Candidate VAR2CSA Molecular and Biochemical Parasitology. Oct, 2007 | Pubmed ID: 17669514 CDNA Sequences Reveal Considerable Gene Prediction Inaccuracy in the Plasmodium Falciparum Genome BMC Genomics. 2007 | Pubmed ID: 17662120 Typing Plasmodium Yoelii Microsatellites Using a Simple and Affordable Fluorescent Labeling Method Molecular and Biochemical Parasitology. Oct, 2007 | Pubmed ID: 17658627 PfGCN5-mediated Histone H3 Acetylation Plays a Key Role in Gene Expression in Plasmodium Falciparum Eukaryotic Cell. Jul, 2007 | Pubmed ID: 17449656 Genome-wide Variation and Identification of Vaccine Targets in the Plasmodium Falciparum Genome Nature Genetics. Jan, 2007 | Pubmed ID: 17159981 CD4+ T-cell Response to Mitochondrial Cytochrome B in Human Melanoma Cancer Research. Jun, 2006 | Pubmed ID: 16740732 Global Genetic Diversity and Evolution of Var Genes Associated with Placental and Severe Childhood Malaria Molecular and Biochemical Parasitology. Aug, 2006 | Pubmed ID: 16697476 Upregulation of Expression of the Reticulocyte Homology Gene 4 in the Plasmodium Falciparum Clone Dd2 is Associated with a Switch in the Erythrocyte Invasion Pathway Molecular and Biochemical Parasitology. Feb, 2006 | Pubmed ID: 16289357 Disruption of a Plasmodium Falciparum Gene Linked to Male Sexual Development Causes Early Arrest in Gametocytogenesis Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16275909 Recombination Hotspots and Population Structure in Plasmodium Falciparum PLoS Biology. Oct, 2005 | Pubmed ID: 16144426 Host Switch Leads to Emergence of Plasmodium Vivax Malaria in Humans Molecular Biology and Evolution. Aug, 2005 | Pubmed ID: 15858201 Genetic Mapping in the Human Malaria Parasite Plasmodium Falciparum Molecular Microbiology. Sep, 2004 | Pubmed ID: 15341640 Pfcrt Polymorphism and the Spread of Chloroquine Resistance in Plasmodium Falciparum Populations Across the Amazon Basin The Journal of Infectious Diseases. Jul, 2004 | Pubmed ID: 15216481 Dissecting the Loci of Low-level Quinine Resistance in Malaria Parasites Molecular Microbiology. May, 2004 | Pubmed ID: 15130119 Polymorphism in the Plasmodium Falciparum Erythrocyte-binding Ligand JESEBL/EBA-181 Alters Its Receptor Specificity Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14983041 Molecular and Biochemical Parasitology. Jan, 2004 | Pubmed ID: 14668019 The "Malaria's Eve" Hypothesis and the Debate Concerning the Origin of the Human Malaria Parasite Plasmodium Falciparum Microbes and Infection / Institut Pasteur. Aug, 2003 | Pubmed ID: 12919857 Multiple Transporters Associated with Malaria Parasite Responses to Chloroquine and Quinine Molecular Microbiology. Aug, 2003 | Pubmed ID: 12890022 Single-nucleotide Polymorphisms and Genome Diversity in Plasmodium Vivax Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12799466 Early Origin and Recent Expansion of Plasmodium Falciparum Science (New York, N.Y.). Apr, 2003 | Pubmed ID: 12690197 Polymorphism in a Plasmodium Falciparum Erythrocyte-binding Ligand Changes Its Receptor Specificity The Journal of Experimental Medicine. Dec, 2002 | Pubmed ID: 12461087 Microsatellite Analysis in Plasmodium Falciparum Methods in Molecular Medicine. 2002 | Pubmed ID: 12125109 Chromosome-wide SNPs Reveal an Ancient Origin for Plasmodium Falciparum Nature. Jul, 2002 | Pubmed ID: 12124624 Genetic Diversity and Chloroquine Selective Sweeps in Plasmodium Falciparum Nature. Jul, 2002 | Pubmed ID: 12124623 Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium Falciparum Molecular Pharmacology. Jan, 2002 | Pubmed ID: 11752204 Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites Sittiporn Pattaradilokrat1, Jian Li1,2, Xin-zhuan Su1 1National Institute of Allergy and Infectious Diseases, National Institutes of Health, 2School of Life Science, Xiamen University JoVE 2365 Immunology and Infection
Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites Sittiporn Pattaradilokrat1, Jian Li1,2, Xin-zhuan Su1 1National Institute of Allergy and Infectious Diseases, National Institutes of Health, 2School of Life Science, Xiamen University JoVE 2365 Immunology and Infection