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Musculoskeletal System

Calcium Control in Muscle Contraction

Description

Calcium control in muscle contraction depends on ATP, motor neurons, and the sliding action of actin and myosin. As a muscle contracts, the thin and thick filaments overlap more, and the sarcomere, which is the contractile unit of the muscle, becomes shorter. This process uses energy from ATP and happens in a repeating cycle...

Transcript

当细丝和粗丝的

重叠增加时 肌肉收缩

导致肌节长度减小

在分子水平上 当与肌球蛋白的

球状头部区域结合的ATP水解成ADP时

发生收缩 将肌球蛋白头转化为高能状态

其中它与肌动蛋白结合

并产生交叉桥

ADP的释放导致肌球蛋白头部

恢复到低能量状态

使肌动蛋白朝向肌节中心移动

新的ATP分子与肌球蛋白头的结合

然后将其与肌动蛋白解离

下一次这个肌球蛋白头部

与肌动蛋白结合时

它将位于更接近Z线...

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